GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **726 - 750** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Cellular response to mitochondrial stress	ATP-dependent zinc metalloprotease YME1L1 DAP3-binding cell death enhancer 1 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3, X-linked Eukaryotic translation initiation factor 2-alpha kinase 1 Metalloendopeptidase OMA1, mitochondrial Prohibitin-2 Stomatin-like protein 2, mitochondrial	A0A8I6G5P0 D3ZS74 P60924 P68101 P81795 Q4FZT0 Q5XIH7 Q63185 Q925S8	Bcap37 Dele Dele1 Eif2a Eif2ak1 Eif2g Eif2s1 Eif2s2 Eif2s3 Eif2s3x Hri Oma1 Phb2 Stoml2 Yme1l1	Rattus norvegicus (Norway rat)
PERK regulates gene expression	Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3, X-linked Eukaryotic translation initiation factor 2-alpha kinase 3	A0A8I6G5P0 P68101 P81795 Q9Z1Z1	Eif2a Eif2ak3 Eif2g Eif2s1 Eif2s2 Eif2s3 Eif2s3x Pek Perk	Rattus norvegicus (Norway rat)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin B1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein R-Ras Rho GTPase-activating protein 35 Rho family GTPase 1 Semaphorin 4D Transforming protein RhoA	A0A8I6G5Q1 D3Z8L7 D3ZDX5 P61589 P81128 P97523 Q5FVG9 Q6RUV5	Arha Arha2 Arhgap35 Grlf1 Met P190A Plxnb1 Rac Rac1 Rhoa Rnd1 Rras Sema4d p190ARHOGAP	Rattus norvegicus (Norway rat)
Attenuation phase	DnaJ heat shock protein family (Hsp40) member B1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock transcription factor 1 Heat shock-related 70 kDa protein 2 Histone lysine acetyltransferase CREBBP Peptidyl-prolyl cis-trans isomerase FKBP4 Prostaglandin E synthase 3 histone acetyltransferase	A0A8I6G641 D3ZUU5 F1MAF1 P0DMW0 P0DMW1 P14659 P34058 P55063 P63018 P82995 P83868 Q6JHU9 Q8K3X8 Q9QVC8	Cbp Crebbp Dnajb1 Ep300 Fkbp4 Fkbp52 Hsbp1 Hsc70 Hsc73 Hsf1 Hsp70-1 Hsp70-2 Hsp70-3 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hspc3 Hspca Hspcb Hst70 Ptges3 Tebp	Rattus norvegicus (Norway rat)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	Catenin beta-1 Histone lysine acetyltransferase CREBBP Interferon regulatory factor 3 histone acetyltransferase	A0A8I6G641 F7EXX5 Q6JHU9 Q9WU82	Catnb Cbp Crebbp Ctnnb1 Ep300 Irf3	Rattus norvegicus (Norway rat)
Nuclear events mediated by NFE2L2	Histone lysine acetyltransferase CREBBP Nuclear factor erythroid 2-related factor 2 histone acetyltransferase	A0A8I6G641 O54968 Q6JHU9	Cbp Crebbp Ep300 Nfe2l2 Nrf2	Rattus norvegicus (Norway rat)
Heme biosynthesis	5-aminolevulinate synthase, erythroid-specific, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial 5-aminolevulinate synthase Albumin Amine oxidase Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome c oxidase assembly homolog COX15 Delta-aminolevulinic acid dehydratase Ferrochelatase Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial Porphobilinogen deaminase Protoheme IX farnesyltransferase, mitochondrial Uroporphyrinogen decarboxylase (Fragment) uroporphyrinogen-III synthase	A0A8I6GEM4 D3ZVN7 D4A414 F1LVF4 F1LVW9 P02770 P06214 P13195 P19356 P32362 Q3B7D0 Q5XIF2 Q63147 Q80W57	Abcg2 Alad Alas1 Alas2 Alase Alb Bcrp1 Cox10 Cox15 Cpo Cpox Fech Hmbs LOC100911779 Ppox Urod Uros	Rattus norvegicus (Norway rat)
Attachment of GPI anchor to uPAR	GPI inositol-deacylase GPI transamidase component PIG-S Glycosylphosphatidylinositol anchor attachment 1 Phosphatidylinositol glycan anchor biosynthesis class U protein Phosphatidylinositol glycan anchor biosynthesis, class T Urokinase plasminogen activator surface receptor	A0A8I6GIH3 F7EVW7 P49616 Q5XI31 Q765A7 Q8CHJ1	Cdc91l1 Gpaa1 Pgap1 Pigs Pigt Pigu Plaur	Rattus norvegicus (Norway rat)
Ethanol oxidation	Acetyl-coenzyme A synthetase Alcohol dehydrogenase 1 Alcohol dehydrogenase 6 Alcohol dehydrogenase class-3 Aldehyde dehydrogenase 1A1 Aldehyde dehydrogenase X, mitochondrial Aldehyde dehydrogenase, mitochondrial All-trans-retinol dehydrogenase [NAD(+)] ADH4 All-trans-retinol dehydrogenase [NAD(+)] ADH7 Propionate--CoA ligase	A0A8I6GJ11 D3ZZN3 P06757 P11884 P12711 P41682 P51647 Q5XI95 Q64563 Q66HF8	Acss1 Acss2 Adh-1 Adh-2 Adh1 Adh2 Adh4 Adh5 Adh6 Adh7 Aldh Aldh1a1 Aldh1b1 Aldh2 Aldhx	Rattus norvegicus (Norway rat)
Synthesis of IP2, IP, and Ins in the cytosol	Inositol monophosphatase 1 Inositol monophosphatase 2 Inositol oxygenase Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase A Inositol-3-phosphate synthase 1 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Synaptojanin-1 Type II inositol 3,4-bisphosphate 4-phosphatase inositol-1,4-bisphosphate 1-phosphatase phosphoinositide 5-phosphatase	A0A8I6GJG8 D3ZGS3 D3ZZX1 D4A2N2 P97697 Q62784 Q62910 Q6AYK3 Q8CIN7 Q9JMC1 Q9QWG5 Q9QXN4	Aldrl6 Imp Impa1 Impa2 Ino1 Inpp1 Inpp4a Inpp4b Inpp5a Inpp5b Inpp5j Isyna1 Ksp32 Miox Ocrl Pib5pa Pipp Rsor Synj1	Rattus norvegicus (Norway rat)
WNT mediated activation of DVL	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Segment polarity protein dishevelled homolog DVL-1 non-specific serine/threonine protein kinase	A0A8I6GKX7 D3ZB71 F7FH41 P19139 P67874 Q5CZZ9 Q99PS2 Q9WVB9	Ck1e-2 Ck2n Csnk1e Csnk2a1 Csnk2a2 Csnk2b Dvl1 Dvl2 Dvl3 LOC100361515 Pip5k1b	Rattus norvegicus (Norway rat)
Defensins	Alpha-defensin N-terminal domain-containing protein Beta-defensin 14 Beta-defensin 17 Beta-defensin 18 Beta-defensin 1 Beta-defensin 25 Beta-defensin 30 Beta-defensin 41 Beta-defensin 43 Beta-defensin 4 Beta-defensin Beta-defensin Beta-defensin Beta-defensin Defensin alpha 10 Defensin alpha 11 Defensin alpha 24 Defensin alpha 4 Defensin alpha 6 Defensin alpha 8 Defensin alpha 9 Defensin alpha-like protein 1 Neutrophil antibiotic peptide NP-2 Neutrophil antibiotic peptide NP-3B	A0A8I6GLV0 A0A8J8YAJ6 F1LSU5 F7EMF7 F7FD31 O88514 O89117 Q32ZF3 Q32ZF5 Q32ZG2 Q32ZG7 Q32ZH1 Q32ZH4 Q32ZH5 Q32ZH7 Q4JEI2 Q4JEI3 Q4JEI5 Q4JEI6 Q4JEI8 Q4JEI9 Q62714 Q62715 Q9Z1F1	Defa Defa-rs1 Defa10 Defa11 Defa24 Defa6 Defa8 Defa9 Defal1 Defb1 Defb14 Defb17 Defb18 Defb2 Defb21 Defb24 Defb25 Defb28 Defb3 Defb30 Defb36 Defb4 Defb41 Defb43 Defcr4 ENSRNOG00000064390 Np4 Rd5	Rattus norvegicus (Norway rat)
Inositol transporters	Proton myo-inositol cotransporter Sodium/myo-inositol cotransporter 2 Solute carrier family 5 member 3	A0A8I6GM79 Q921A2 Q9Z1F2	Kst1 Slc2a13 Slc5a11 Slc5a3 Smit2	Rattus norvegicus (Norway rat)
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Core-binding factor subunit beta Forkhead box P3 Runt-related transcription factor 1	A0A8I6GMB2 D4Q8I2 Q63046	Aml1 Cbfa2 Cbfb Foxp3 Runx1	Rattus norvegicus (Norway rat)
RUNX1 regulates transcription of genes involved in interleukin signaling	Core-binding factor subunit beta E74 like ETS transcription factor 1 Runt-related transcription factor 1	A0A8I6GMB2 G3V9V2 Q63046	Aml1 Cbfa2 Cbfb Elf1 Runx1	Rattus norvegicus (Norway rat)
RUNX1 regulates estrogen receptor mediated transcription	Core-binding factor subunit beta Estrogen receptor Runt-related transcription factor 1	A0A8I6GMB2 P06211 Q63046	Aml1 Cbfa2 Cbfb Esr Esr1 Estr Nr3a1 Runx1	Rattus norvegicus (Norway rat)
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	Core-binding factor subunit beta Histone lysine acetyltransferase CREBBP Runt-related transcription factor 1	A0A8I6GMB2 Q63046 Q6JHU9	Aml1 Cbfa2 Cbfb Cbp Crebbp Runx1	Rattus norvegicus (Norway rat)
HuR (ELAVL1) binds and stabilizes mRNA	Acidic leucine-rich nuclear phosphoprotein 32 family member A ELAV-like protein 1 Exportin-1 Nucleoporin 214 Protein SET Protein kinase C alpha type Protein kinase C delta type TNF superfamily member 13	A0A8J8XC20 B5DF91 D4ACK1 P05696 P09215 P49911 Q63945 Q80U96	Anp32a Crm1 Elavl1 Hur Lanp Nup214 Pkca Pkcd Prkca Prkcd Set Tnfsf13 Xpo1	Rattus norvegicus (Norway rat)
Synthesis, secretion, and deacylation of Ghrelin	Appetite-regulating hormone Carboxylic ester hydrolase Ghrelin O-acyltransferase Insulin-1 Insulin-like growth factor I Leptin Neuroendocrine convertase 1 Pro-glucagon Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Somatotropin	A0A8J8XQI9 B1Q005 D3ZD11 D3ZF12 D3ZFK5 P01244 P01322 P06883 P08025 P28840 P42667 P50596 Q9QYH7 Q9WTR7	Bche Bdp Gcg Gh Gh1 Ghrl Goat Igf-1 Igf1 Ins-1 Ins1 Lep Mboat4 Nec-1 Nec1 Ob Pcsk1 Sec11a Sec11c Sec11l1 Sec11l3 Spc18 Spc21 Spcs1 Spcs2 Spcs3	Rattus norvegicus (Norway rat)	G58161NS
Acetylcholine regulates insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha Myristoylated alanine-rich C-kinase substrate Protein kinase C alpha type	A0A8J8XRQ3 O88302 O89040 P05696 P10687 P30009 P82471 Q99JE6 Q9JID2	Gna11 Gna14 Gna15 Gnaq Macs Marcks Pkca Plcb1 Plcb2 Plcb3 Prkca	Rattus norvegicus (Norway rat)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha	A0A8J8XRQ3 O88302 O89040 P10687 P82471 Q8K3T4 Q99JE6 Q9JID2	Ffar1 Gna11 Gna14 Gna15 Gnaq Gpr40 Plcb1 Plcb2 Plcb3	Rattus norvegicus (Norway rat)
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha	A0A8J8XRQ3 O88302 O89040 P10687 P82471 Q99JE6 Q9JID2 Q9QW07	Gna11 Gna14 Gna15 Gnaq Plcb1 Plcb2 Plcb3 Plcb4	Rattus norvegicus (Norway rat)
ADP signalling through P2Y purinoceptor 1	Cytosolic phospholipase A2 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha Mitogen-activated protein kinase 14 P2Y purinoceptor 1 Proto-oncogene tyrosine-protein kinase Src	A0A8J8XRQ3 O88302 P49651 P50393 P70618 P82471 Q9JID2 Q9WUD9	Cpla2 Csbp1 Csbp2 Gna11 Gna14 Gna15 Gnaq Mapk14 P2ry1 Pla2g4 Pla2g4a Src	Rattus norvegicus (Norway rat)
Activation of C3 and C5	Complement C2 Complement C3 Complement C4 Complement C4B (Chido blood group) Complement C5	A0A8J8YKQ8 P01026 P08649 P08650 Q6MG90	C2 C3 C4 C4a C4b C5 Cfb	Rattus norvegicus (Norway rat)
Peroxisomal lipid metabolism	2-Hydroxyacid oxidase 2 Acyl-CoA-binding domain-containing protein 4 Acyl-CoA-binding domain-containing protein 5 Acyl-coenzyme A diphosphatase NUDT19	A0FKI7 Q07523 Q6AYD9 Q6DGF9	Acbd4 Acbd5 Hao2 Hao3 Haox2 Nudt19	Rattus norvegicus (Norway rat)

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