GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **776 - 800** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
The retinoid cycle in cones (daylight vision)	Acyltransferase Medium-wave-sensitive opsin 1 Retinaldehyde binding protein 1 Retinol binding protein 3 Short-wave-sensitive opsin 1	D3Z956 D4A598 G3V8Q4 O35476 Q63652	Awat2 Bcp Gcp Opn1mw Opn1sw Rbp3 Rlbp1	Rattus norvegicus (Norway rat)
Hydrolysis of LPC	Cytosolic phospholipase A2 Lysosomal phospholipase A and acyltransferase Phospholipase A2 group IVC Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1	D3Z9B7 D3ZQH6 D4A1I6 F1LMQ4 F1LPY6 P50393 Q5U2V4 Q675A5	Cpla2 Lypla3 Pla2g15 Pla2g4 Pla2g4a Pla2g4b Pla2g4c Pla2g4d Pla2g4e Pla2g4f Plbd1	Rattus norvegicus (Norway rat)
Acyl chain remodeling of DAG and TAG	Acyltransferase Acyltransferase Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2 Monoglyceride lipase Patatin-like phospholipase domain containing 3 Patatin-like phospholipase domain-containing protein 2	D3Z9J9 D3ZTG7 D4A598 P0C548 Q5FVP8 Q8R431 Q9ERM3	Atgl Awat2 Dgat Dgat1 Dgat2 Dgat2l6 Mgl2 Mgll Pnpla2 Pnpla3	Rattus norvegicus (Norway rat)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial Copine 3 Copine 6 Copine-1 Copine-7	D3Z9L0 D3ZLA3 D4A1R8 D4ACG7 H1UBN0	Agk Cpne1 Cpne3 Cpne6 Cpne7	Rattus norvegicus (Norway rat)
Metal sequestration by antimicrobial proteins	Lactotransferrin Neutrophil gelatinase-associated lipocalin Protein S100-A8 Protein S100-A9	D3ZAB1 P30152 P50115 P50116	Lcn2 Ltf Mrp14 Mrp8 S100a8 S100a9	Rattus norvegicus (Norway rat)
Cristae formation	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial	D3ZAF6 P05504 P10719 P11608 P15999 P19511 P21571 P29418 P29419 P31399 P35434 P35435 Q06645 Q06646 Q06647 Q5XIM4 Q6PDU7 Q71S46	Atp5a1 Atp5b Atp5c Atp5c1 Atp5d Atp5e Atp5f Atp5f1 Atp5f1a Atp5f1b Atp5f1c Atp5f1d Atp5f1e Atp5g1 Atp5g2 Atp5g3 Atp5h Atp5i Atp5j Atp5j2 Atp5jd Atp5l Atp5mc1 Atp5mc2 Atp5mc3 Atp5me Atp5mf Atp5mg Atp5o Atp5pb Atp5pd Atp5pf Atp5po Atp5s Atp6 Atp8 Atpase6 Atpase8 Dmac2l Mt-atp6 Mt-atp8 Mtatp6 Mtatp8	Rattus norvegicus (Norway rat)
Formation of ATP by chemiosmotic coupling	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial	D3ZAF6 P05504 P10719 P11608 P15999 P19511 P21571 P29418 P29419 P31399 P35434 P35435 Q06645 Q06646 Q06647 Q5XIM4 Q6PDU7 Q71S46	Atp5a1 Atp5b Atp5c Atp5c1 Atp5d Atp5e Atp5f Atp5f1 Atp5f1a Atp5f1b Atp5f1c Atp5f1d Atp5f1e Atp5g1 Atp5g2 Atp5g3 Atp5h Atp5i Atp5j Atp5j2 Atp5jd Atp5l Atp5mc1 Atp5mc2 Atp5mc3 Atp5me Atp5mf Atp5mg Atp5o Atp5pb Atp5pd Atp5pf Atp5po Atp5s Atp6 Atp8 Atpase6 Atpase8 Dmac2l Mt-atp6 Mt-atp8 Mtatp6 Mtatp8	Rattus norvegicus (Norway rat)
MET activates PTPN11	GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type 11	D3ZAL7 P17945 P41499 P62994 P97523	Ash Gab1 Grb2 Hgf Met Ptpn11	Rattus norvegicus (Norway rat)
Chylomicron clearance	Apolipoprotein B-100 Apolipoprotein E Hepatic triacylglycerol lipase Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor	D3ZAR1 P02650 P07867 P35952 Q7TMA5	Apob Apoe Arh Ldlr Ldlrap1 Lipc	Rattus norvegicus (Norway rat)
Transport of RCbl within the body	CD320 antigen Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Multidrug resistance-associated protein 1 Transcobalamin-2	D3ZAR1 P98158 Q5HZW5 Q8CG09 Q9R0D6	Abcc1 Arh Cd320 Ldlrap1 Lrp2 Mrp1 Tcn2	Rattus norvegicus (Norway rat)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Dynamin-2 Dynamin-3 Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain containing adaptor molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type	D3ZAS0 D3ZIP2 D3ZXR7 G3V6B9 P21575 P24135 P39052 Q08877 Q56DL5 Q63313 Q63691 Q6AXU0 Q9QX05	Bpi Cd14 Cd180 Dnm Dnm1 Dnm2 Dnm3 Dyn2 Dyn3 Lbp Ly86 Ly96 Plcg2 Ptpn4 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
FOXO-mediated transcription of cell cycle genes	Forkhead box O3 Forkhead box O4 Forkhead box protein G1 Forkhead box protein O1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	D3ZBQ1 D4A433 G3V7R4 O70436 O70437 P84025 Q00939	Fkhl1 Foxg1 Foxg1b Foxo1 Foxo1a Foxo3 Foxo4 Madh2 Madh3 Madh4 Smad2 Smad3 Smad4	Rattus norvegicus (Norway rat)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Cyclic AMP-responsive element-binding protein 1 Cyclin-dependent kinase inhibitor 1B Exportin-1 Forkhead box O3 Mitogen-activated protein kinase 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein kinase Kist	D3ZBQ1 O08769 P15337 P47196 P47197 P63086 Q63285 Q63484 Q80U96	Akt1 Akt2 Akt3 Cdkn1b Creb-1 Creb1 Crm1 Erk2 Foxo3 Kis Kist Mapk Mapk1 Prkm1 Uhmk1 Xpo1 p27Kip1	Rattus norvegicus (Norway rat)
Signaling by NODAL	Forkhead box O3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	D3ZBQ1 O70436 O70437 P21708 P63086 P84025	Erk1 Erk2 Foxo3 Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Smad2 Smad3 Smad4	Rattus norvegicus (Norway rat)
Sodium/Proton exchangers	Sodium/hydrogen exchanger 1 Sodium/hydrogen exchanger 2 Sodium/hydrogen exchanger 3 Sodium/hydrogen exchanger 4 Sodium/hydrogen exchanger 5 Sodium/hydrogen exchanger 6 Sodium/hydrogen exchanger 8 Sodium/hydrogen exchanger 9 Sodium/hydrogen exchanger	D3ZCI2 D3ZJ86 D4A7H1 P26431 P26433 P26434 P48763 Q4L208 Q9Z0X2	Nhe1 Nhe2 Nhe3 Nhe4 Nhe5 Nhe8 Nhe9 Slc9a1 Slc9a2 Slc9a3 Slc9a4 Slc9a5 Slc9a6 Slc9a7 Slc9a8 Slc9a9	Rattus norvegicus (Norway rat)
Interleukin-23 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 23 receptor Interleukin-12 subunit beta Interleukin-23 subunit alpha Protein disulfide-isomerase Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	D3ZD03 E9PSU7 E9PU71 F1LX96 P04785 P52631 Q62689 Q91Z84	IL12B Il12b Il12rb1 Il23a Il23r Jak2 P4hb Pdia1 Stat3 Tyk2	Rattus norvegicus (Norway rat)
Scavenging by Class A Receptors	Apolipoprotein A-I Apolipoprotein B-100 Apolipoprotein E Calreticulin Endoplasmin Macrophage receptor with collagenous structure Macrophage scavenger receptor 1 Secretoglobin, family 3A, member 2	D3ZDS2 F7FAW3 M0R9F7 P02650 P04639 P18418 Q66HD0 Q7TMA5	Apoa1 Apob Apoe Calr Grp94 Hsp90b1 Hspc4 Marco Msr1 Scgb3a2 Tra1	Rattus norvegicus (Norway rat)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Engulfment and cell motility 1 Engulfment and cell motility 2 GTPase HRas GTPase KRas GTPase NRas Paxillin Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Transforming protein RhoA Tyrosine-protein kinase	D3ZDS3 D3ZY46 G3V982 P08644 P20171 P50904 P61589 P81128 Q04970 Q63767 Q63768 Q66H76 Q6RUV5	Arha Arha2 Arhgap35 Bcar1 Cas Crk Crkas Crko Elmo1 Elmo2 Grlf1 Hras Hras1 Kras Kras2 Nras P190A Ptk6 Pxn Rac Rac1 Rasa Rasa1 Rhoa p190ARHOGAP	Rattus norvegicus (Norway rat)
PTK6 promotes HIF1A stabilization	Hypoxia-inducible factor 1-alpha Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transmembrane glycoprotein NMB Tyrosine-protein kinase non-specific serine/threonine protein kinase	D3ZDS3 F1LNJ1 G3V6K6 O35800 Q06175 Q6P7C7	Dtr Egfr Gpnmb Hbegf Hegfl Hif1a Lrrk2 Ptk6	Rattus norvegicus (Norway rat)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Tyrosine-protein kinase	D3ZDS3 O08769 P35426 P39948 P39949 Q63699	Ccnd1 Ccne Ccne1 Cdk2 Cdk4 Cdkn1b Cdkn2 Ptk6 p27Kip1	Rattus norvegicus (Norway rat)
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase-1 Hyaluronidase-3 Iduronate 2-sulfatase Neurocan core protein Versican core protein (Fragments)	D3ZE16 F1LLW8 P47853 P50430 P55067 P55068 Q00657 Q01129 Q641X3 Q6AXR4 Q76HM9 Q76HN1 Q9ERB4 Q9ERQ6	Arsb Bcan Behab Bgn Caleb Cspg2 Cspg3 Cspg4 Cspg5 Dcn Hexa Hexb Hyal1 Hyal3 Ids Idua LOC100363795 Ncan Ng2 Ngc Vcan	Rattus norvegicus (Norway rat)	G27025MB
HDL clearance	Apolipoprotein A-I Cubilin Protein amnionless Scavenger receptor class B member 1 Vigilin	D3ZFK9 O70244 P04639 P97943 Q9Z1A6	Amn Apoa1 Cubn Hbp Hdlbp Ifcr Scarb1	Rattus norvegicus (Norway rat)
Uptake of dietary cobalamins into enterocytes	Cobalamin binding intrinsic factor Cubilin Protein amnionless	D3ZFK9 O70244 P17267	Amn Cblif Cubn Gif Ifcr	Rattus norvegicus (Norway rat)
RA biosynthesis pathway	Alcohol dehydrogenase 1 Aldehyde dehydrogenase 1A1 Aldehyde dehydrogenase 8 family, member A1 Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Cellular retinoic acid-binding protein 1 Cytochrome P450 26A1 Cytochrome P450 26B1 Cytochrome P450, family 26, subfamily C, polypeptide 1 Dehydrogenase/reductase SDR family member 4 Dehydrogenase/reductase SDR family member 9 LRRGT00111 Retinal dehydrogenase 2 Retinaldehyde dehydrogenase 3 Retinol dehydrogenase 10 Retinol dehydrogenase 13 Retinol dehydrogenase 14 Retinol dehydrogenase 7 Short chain dehydrogenase/reductase family 16C, member 5	D3ZFR9 D3ZS85 D3ZUY0 D3ZXY4 D4AAL3 G3V7X8 G3V861 P06757 P51647 P55006 P62966 Q3MHS3 Q63639 Q64563 Q6AYQ2 Q6TUD3 Q80ZF7 Q8K4D8 Q8VD48 Q8VID1	Adh-1 Adh1 Adh2 Adh4 Akr1c1 Akr1c21 Aldh Aldh1a1 Aldh1a2 Aldh1a3 Aldh6 Aldh8a1 Crabp1 Cyp26a1 Cyp26b1 Cyp26c1 Dhrs4 Dhrs9 Hsd17b5 LOC683474 Raldh2 Raldh3 Rdh10 Rdh11 Rdh13 Rdh14 Rdh3 Rdh7 Sdr16c5 eRolDH	Rattus norvegicus (Norway rat)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	D3ZGB8 P01346 P08025 P24062	Cilp Igf-1 Igf-2 Igf1 Igf1r Igf2	Rattus norvegicus (Norway rat)

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