GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **826 - 850** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05 Q9Z2P5	Casp8 Cd14 Fadd Ly96 Plin3 Rip3 Ripk1 Ripk3 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05	Casp8 Cd14 Fadd Ly96 Plin3 Ripk1 Ticam1 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Zinc efflux and compartmentalization by the SLC30 family	Proton-coupled zinc antiporter SLC30A1 Proton-coupled zinc antiporter SLC30A8 Zinc transporter	D3ZY54 P0CE46 Q62720	Slc30a1 Slc30a5 Slc30a8 Znt1 Znt8	Rattus norvegicus (Norway rat)
Chylomicron remodeling	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Lipoprotein lipase	D3ZZL5 G3V8D4 P02650 P02651 P04638 P04639 P06759 Q06000 Q7TMA5 Q9QUH3	Apoa1 Apoa2 Apoa4 Apoa5 Apob Apoc2 Apoc3 Apoe Gpihbp1 Lpl Rap3	Rattus norvegicus (Norway rat)
Presynaptic depolarization and calcium channel opening	Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2 Voltage-dependent calcium channel subunit alpha-2/delta-3	D4A055 P54282 P54283 P54287 Q02294 Q07652 Q71RJ2 Q8CFG5 Q8CFG6 Q8VGC3 Q8VHW9	Cach4 Cach5 Cach6 Cacn3 Cacna1a Cacna1b Cacna1e Cacna2d2 Cacna2d3 Cacnb1 Cacnb2 Cacnb3 Cacnb4 Cacng2 Cacng4 Cacnl1a4 Cacnl1a5 Cacnl1a6 Cacnlb1 Cacnlb2 Cacnlb3 Stg	Rattus norvegicus (Norway rat)
Amine ligand-binding receptors	G protein-coupled receptor 143 Trace amine-associated receptor 1 Trace amine-associated receptor 2 Trace amine-associated receptor 3 Trace amine-associated receptor 5 Trace amine-associated receptor 6 Trace amine-associated receptor 8a Trace amine-associated receptor 8c Trace amine-associated receptor 9	D4A082 Q5QD23 Q5QD24 Q5QD25 Q923X9 Q923Y0 Q923Y5 Q923Y6 Q923Y9	Gpr143 Gpr58 Ta1 Ta10 Ta11 Ta3 Ta4 Taar1 Taar2 Taar3 Taar5 Taar6 Taar8a Taar8c Taar9 Tar1 Tar10 Tar11 Tar3 Tar4 Trar1 Trar10 Trar11 Trar3 Trar4	Rattus norvegicus (Norway rat)
Chylomicron assembly	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase Small COPII coat GTPase SAR1B	D4A1W8 G3V8D4 P02650 P02651 P04638 P04639 P04785 P06759 Q5HZY2 Q7TMA5	Apoa1 Apoa2 Apoa4 Apob Apoc2 Apoc3 Apoe Mtp Mttp P4hb Pdia1 Sar1b	Rattus norvegicus (Norway rat)
VLDL assembly	Apolipoprotein B-100 Apolipoprotein C-I Apolipoprotein C-IV Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	D4A1W8 P04785 P19939 P55797 Q7TMA5	Apob Apoc1 Apoc4 Ecl Mtp Mttp P4hb Pdia1	Rattus norvegicus (Norway rat)
LDL remodeling	Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	D4A1W8 P04785	Mtp Mttp P4hb Pdia1	Rattus norvegicus (Norway rat)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Growth factor receptor-bound protein 2 Neurotrophin-4 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A244 D4A3T0 P23363 P34131 P62994 Q63604	Ash Bdnf Frs2 Grb2 Nt4 Ntf4 Ntf5 Ntrk2 Sos1 Trkb	Rattus norvegicus (Norway rat)
Tight junction interactions	Junctional adhesion molecule A Par-6 family cell polarity regulator beta Par-6 family cell polarity regulator gamma Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Protein kinase C iota type	D4A2F2 E9PT71 F1M7Y5 Q6B4M5 Q9JHY1 Q9Z340	F11r Jam1 Par-6a Par3 Par6a Pard3 Pard6a Pard6b Pard6g Pkcl Prkci	Rattus norvegicus (Norway rat)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3 adenylate cyclase	D4A3N4 F1LQT1 M0R5U4 P04897 P08753 P10824 P21932 P26769 P26770 P29348 P38406 P40146 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnal Gnat-3 Gnat3	Rattus norvegicus (Norway rat)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Calmodulin-3 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	D4A3N4 F1LQT1 M0R5U4 P09456 P0DP31 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 CaMIII Calm3 Cam3 Camc Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b	Rattus norvegicus (Norway rat)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Guanine nucleotide-binding protein G(olf) subunit alpha adenylate cyclase	D4A3N4 F1LQT1 M0R5U4 P21932 P26769 P26770 P38406 P40146 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Gnal	Rattus norvegicus (Norway rat)
Signal attenuation	Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin-1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 F1MAL5 P01322 P0CE43 P15127 P21708 P35570 P62994 P63086 Q5M824	Ash Erk1 Erk2 Grb10 Grb2 Ins-1 Ins1 Insr Irs-1 Irs1 Irs2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Shc1 Sos1	Rattus norvegicus (Norway rat)
SOS-mediated signalling	Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 F1MAL5 P35570 P62994	Ash Grb2 Irs-1 Irs1 Irs2 Sos1	Rattus norvegicus (Norway rat)
EGFR Transactivation by Gastrin	GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C alpha type Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1	D4A3T0 G3V6K6 P03957 P05696 P08644 P20171 P62994 Q04970 Q06175	Ash Dtr Egfr Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Mmp3 Nras Pkca Prkca Sos1	Rattus norvegicus (Norway rat)
Signalling to RAS	Growth factor receptor-bound protein 2 SHC-transforming protein 1 SHC-transforming protein 2 SHC-transforming protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 O70142 O70143 P62994 Q5M824	Ash Grb2 Nshc Sck Shc1 Shc2 Shc3 Shcc Sos1	Rattus norvegicus (Norway rat)
Insulin receptor signalling cascade	Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Insulin receptor Insulin-1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 P01322 P0CE43 P15127 P62994 Q5M824	Ash Grb10 Grb2 Ins-1 Ins1 Insr Shc1 Sos1	Rattus norvegicus (Norway rat)
SHC-related events triggered by IGF1R	Growth factor receptor-bound protein 2 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 P01346 P08025 P24062 P62994 Q5M824	Ash Grb2 Igf-1 Igf-2 Igf1 Igf1r Igf2 Shc1 Sos1	Rattus norvegicus (Norway rat)
p38MAPK events	GTPase HRas GTPase KRas GTPase NRas MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mapk11 protein Mitogen-activated protein kinase 14 Ral guanine nucleotide dissociation stimulator	D4A3U7 P08644 P20171 P70618 Q03386 Q04970 Q66H84 Q80ZF4	Csbp1 Csbp2 Hras Hras1 Kras Kras2 Mapk11 Mapk14 Mapkapk2 Mapkapk3 Nras Ralgds	Rattus norvegicus (Norway rat)
Activation of the AP-1 family of transcription factors	Cyclic AMP-dependent transcription factor ATF-2 Mapk11 protein Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Protein c-Fos Transcription factor Jun	D4A3U7 P12841 P17325 P21708 P49185 P49186 P49187 P63086 P70618 Q00969	Atf2 Csbp1 Csbp2 Erk1 Erk2 Fos Jnk1 Jnk2 Jnk3 Jun Mapk Mapk1 Mapk10 Mapk11 Mapk14 Mapk3 Mapk8 Mapk9 Prkm1 Prkm10 Prkm3 Prkm8 Prkm9 Rjg-9	Rattus norvegicus (Norway rat)
PDH complex synthesizes acetyl-CoA from PYR	Ac1164 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	D4A5G8 P08461 P26284 P49432 Q06437 Q6P6R2 Q7TQ85	Dlat Dld LOC311254 Pdha1 Pdha1l1 Pdha2 Pdhb Pdhx	Rattus norvegicus (Norway rat)
Methylation	Adenosylhomocysteinase Arsenite methyltransferase Catechol O-methyltransferase Cytochrome P450 1A2 Glutathione S-transferase omega-1 Methionine adenosyltransferase 2 subunit beta Methionine synthase reductase Methionine synthase Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 S-adenosylmethionine synthase isoform type-2 Thiopurine S-methyltransferase	D4A605 P04799 P10760 P13444 P18298 P22734 Q498R1 Q5U2R0 Q8VHT6 Q9Z0T0 Q9Z2Q4 Q9Z339	Ahcy Ams1 Ams2 As3mt Comt Cyp1a-2 Cyp1a2 Cyt19 Gsto1 Mat1a Mat2a Mat2b Mtr Mtrr Nnmt Tpmt	Rattus norvegicus (Norway rat)
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral-signaling protein Mitochondrial import receptor subunit TOM70 TANK-binding kinase 1	D4A7D3 F7EXX5 P34058 P82995 Q66HG9 Q75Q39	Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Ips1 Irf3 Mavs Tbk1 Tomm70 Tomm70a Visa	Rattus norvegicus (Norway rat)

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