GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **851 - 875** of **1070** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
FRS-mediated FGFR3 signaling	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K210 A0A8I6B5D5 D4A244 D4A3T0 F1LSQ8 O54769 O88182 P08644 P13109 P20171 P36364 P41499 P48807 P61149 P62994 P63076 Q04970 Q52RG8 Q8VI82 Q9EST9	Ash Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Frs2 Frs3 Grb2 Hras Hras1 Kras Kras2 Nras Ptpn11 Snt2 Sos1	Rattus norvegicus (Norway rat)
PI-3K cascade:FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K210 A0A0G2K344 A0A8I6B5D5 D3ZAL7 D4A244 F1LSQ8 O54769 O88182 P13109 P36364 P41499 P48807 P61149 P62994 P63076 Q63787 Q8VI82 Q9EST9	Ash Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Frs2 Gab1 Grb2 Pik3ca Pik3r1 Ptpn11	Rattus norvegicus (Norway rat)
SHC-mediated cascade:FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A0G2K210 A0A8I6B5D5 D4A3T0 F1LSQ8 O54769 O88182 P08644 P13109 P20171 P36364 P48807 P61149 P62994 P63076 Q04970 Q5M824 Q8VI82 Q9EST9	Ash Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Grb2 Hras Hras1 Kras Kras2 Nras Shc1 Sos1	Rattus norvegicus (Norway rat)
FGFR3c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor	A0A0G2K210 A0A8I6B5D5 F1LSQ8 O54769 O88182 P13109 P36364 P48807 P61149 P63076 Q8VI82 Q9EST9	Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3	Rattus norvegicus (Norway rat)
FGFR2c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSG7 F1LSQ8 O54769 O88182 P13109 P36364 P48807 P61149 P63076 Q8R5L5 Q8VI82 Q9EST9	FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2	Rattus norvegicus (Norway rat)
FRS-mediated FGFR4 signaling	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Klotho beta SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11	A0A8I6B5D5 D3Z8T6 D4A244 D4A3T0 F1LSQ8 O54769 O88182 P08644 P13109 P20171 P36364 P41499 P61149 P62994 P63076 Q04970 Q498D6 Q52RG8 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Frs2 Frs3 Grb2 Hras Hras1 Klb Kras Kras2 Nras Ptpn11 Snt2 Sos1	Rattus norvegicus (Norway rat)
PI-3K cascade:FGFR4	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Klotho beta Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6B5D5 D3Z8T6 D3ZAL7 D4A244 F1LSQ8 O54769 O88182 P13109 P36364 P41499 P61149 P62994 P63076 Q498D6 Q63787 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Frs2 Gab1 Grb2 Klb Pik3ca Pik3r1 Ptpn11	Rattus norvegicus (Norway rat)
SHC-mediated cascade:FGFR4	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Klotho beta SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6B5D5 D3Z8T6 D4A3T0 F1LSQ8 O54769 O88182 P08644 P13109 P20171 P36364 P61149 P62994 P63076 Q04970 Q498D6 Q5M824 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Grb2 Hras Hras1 Klb Kras Kras2 Nras Shc1 Sos1	Rattus norvegicus (Norway rat)
FGFR4 ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSQ8 O54769 O88182 P13109 P36364 P61149 P63076 Q498D6 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4	Rattus norvegicus (Norway rat)
FGFR1c ligand binding and activation	Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	A0A8I6B5D5 F1LSQ8 P13109 P26342 P36364 P48807 P61149 P63076 Q04589 Q8R5L5 Q8VI82 Q9EST9 Q9Z254	FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf17 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Gipc Gipc1 Rgs19ip1 Tgfbr3	Rattus norvegicus (Norway rat)
FGFR3b ligand binding and activation	Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor	A0A0G2K210 A0A8I6B5D5 O88182 P36364 P61149 P63076 Q9EST9	Fgf-1 Fgf-9 Fgf1 Fgf17 Fgf18 Fgf20 Fgf8 Fgf9 Fgfa Fgfr3	Rattus norvegicus (Norway rat)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor 1 Klotho	Q04589 Q8VI82 Q9Z2Y9	Fgf23 Fgfr1 Flg Kl	Rattus norvegicus (Norway rat)
betaKlotho-mediated ligand binding	Fibroblast growth factor receptor 4 Fibroblast growth factor Klotho beta	D3Z8T6 Q498D6 Q8VI81	FGF15 Fgf19 Fgf8a Fgfr4 Klb	Rattus norvegicus (Norway rat)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B1 Sodium/glucose cotransporter 1 Sodium/glucose cotransporter 2 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 2, facilitated glucose transporter member 7 Solute carrier family 2, facilitated glucose transporter member 8 Solute carrier family 45, member 3 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET1	A0A0G2JY02 A0A8I6AVN8 A4ZYQ5 D3ZH22 D3ZIS0 D3ZNG4 D3ZPP5 D3ZVY8 F1LTM4 F7FG05 G3V8X5 P11167 P12336 P19357 P53790 P53792 Q07647 Q9JJZ1	Fgf21 GLUT7 Glut1 Glut2 Glut3 Glut4 Glut8 Glutx1 Mfsd4b Mfsd4b1 RGD1559971 RGD1561777 Rag1ap1 Rga Sglt1 Sglt2 Slc2a1 Slc2a10 Slc2a12 Slc2a2 Slc2a3 Slc2a4 Slc2a7 Slc2a8 Slc2a9 Slc45a3 Slc50a1 Slc5a1 Slc5a10 Slc5a2 Slc5a4 Slc5a9	Rattus norvegicus (Norway rat)	G58161NS G70323CJ
Extracellular matrix organization	Fibronectin	P04937	Fn1	Rattus norvegicus (Norway rat)
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Ficolin-1 Ficolin-2 Mannan-binding lectin serine protease 1 Mannan-binding lectin serine protease 2	P57756 Q8CHN8 Q9JJS8 Q9WTS8	Crarf Fcn1 Fcn2 Fcna Fcnb Masp1 Masp2 Masp3	Rattus norvegicus (Norway rat)	G49108TO G57321FI
RIPK1-mediated regulated necrosis	Flotillin-1 Flotillin-2 Mixed lineage kinase domain like pseudokinase Programmed cell death 6-interacting protein Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 Syntenin-1	A0A8I5ZV82 D3ZYL0 Q9JI92 Q9QZA2 Q9Z1E1 Q9Z2P5 Q9Z2S9	Aip1 Flot1 Flot2 Mlkl Pdcd6ip Reg1 Reg2 Rip3 Ripk1 Ripk3 Sdcbp	Rattus norvegicus (Norway rat)
MET activates PTK2 signaling	Focal adhesion kinase 1 Hepatocyte growth factor receptor Hepatocyte growth factor Integrin alpha 3 variant B Integrin beta-1 Integrin subunit alpha 2 Laminin subunit alpha 4 Multiple epidermal growth factor-like domains protein 6 Proto-oncogene tyrosine-protein kinase Src	A0A0G2K470 F1LTF8 I4DUB5 O35346 O88281 P17945 P49134 P97523 Q9WUD9	Egfl3 Fak Fak1 Hgf ITGA3B Itga2 Itga3 Itgb1 Lama4 Megf6 Met Ptk2 Src	Rattus norvegicus (Norway rat)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormone alpha-2 Glycoprotein hormone subunit beta 5 Glycoprotein hormones alpha chain Gonadotropin-releasing hormone receptor Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Progonadoliberin-1 Thyrotropin receptor Thyrotropin subunit beta	P01230 P04652 P07490 P11962 P16235 P18427 P20395 P21463 P30969 Q5VJF5 Q925Q4	Cga Cga1 Fshb Fshr Gnrh Gnrh1 Gnrhr Gpa2 Gpb5 Gpha2 Gphb5 Lhb Lhcgr Tshb Tshr Zsig51	Rattus norvegicus (Norway rat)
Antagonism of Activin by Follistatin	Follistatin-related protein 3 Follistatin Inhibin beta A chain Inhibin beta B chain	P17491 P18331 P21674 Q99PW7	Flrg Fst Fstl3 Inhba Inhbb	Rattus norvegicus (Norway rat)
Glycoprotein hormones	Follitropin subunit beta Glycoprotein hormones alpha chain Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Inhibin beta C chain Inhibin beta E chain Lutropin subunit beta Thyrotropin subunit beta	O88959 P01230 P04652 P11962 P17490 P17491 P18331 P18427 Q9WUK5	Cga Cga1 Fshb Inha Inhba Inhbb Inhbc Inhbe Lhb Tshb	Rattus norvegicus (Norway rat)
FOXO-mediated transcription of cell cycle genes	Forkhead box O3 Forkhead box O4 Forkhead box protein G1 Forkhead box protein O1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	D3ZBQ1 D4A433 G3V7R4 O70436 O70437 P84025 Q00939	Fkhl1 Foxg1 Foxg1b Foxo1 Foxo1a Foxo3 Foxo4 Madh2 Madh3 Madh4 Smad2 Smad3 Smad4	Rattus norvegicus (Norway rat)
Regulation of FOXO transcriptional activity by acetylation	Forkhead box O3 Forkhead box protein O1 Histone acetyltransferase Histone lysine acetyltransferase CREBBP NAD-dependent protein deacetylase sirtuin-1 Sirtuin 3 histone acetyltransferase	A0A0G2JZ79 A0A8I5XWT5 A0A8I5Y222 A0A8I6G641 D3ZBQ1 G3V7R4 Q6JHU9	Cbp Crebbp Ep300 Foxo1 Foxo1a Foxo3 Kat2b Sirt1 Sirt3	Rattus norvegicus (Norway rat)
FLT3 Signaling	Forkhead box O3 GRB2-associated-binding protein 2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase SOS Ras/Rac guanine nucleotide exchange factor 1 receptor protein-tyrosine kinase	A0A0G2JW59 A0A0G2K344 D3ZBQ1 D4A3T0 P08644 P0CE43 P20171 P47196 P47197 P62994 Q04970 Q63484 Q63787 Q9EQH1	Akt1 Akt2 Akt3 Ash Flt3 Foxo3 Gab2 Grb10 Grb2 Hras Hras1 Kras Kras2 Nras Pik3ca Pik3r1 Sos1	Rattus norvegicus (Norway rat)
Signaling by NODAL	Forkhead box O3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	D3ZBQ1 O70436 O70437 P21708 P63086 P84025	Erk1 Erk2 Foxo3 Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Smad2 Smad3 Smad4	Rattus norvegicus (Norway rat)

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