GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **901 - 925** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Growth hormone receptor signaling	Growth hormone receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Prolactin receptor Prolactin SH2B adapter protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein phosphatase non-receptor type 1	P01237 P01244 P05710 P16310 P20417 P21708 P52632 P63086 Q07014 Q62689 Q62771 Q62985	Erk1 Erk2 Gh Gh1 Ghr Jak2 Lyn Mapk Mapk1 Mapk3 Mgf Prkm1 Prkm3 Prl Prlr Ptpn1 Sh2-b Sh2b1 Sh2bpsm1 Stat5a Stat5b	Rattus norvegicus (Norway rat)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A8I6AM23 D4A109 F7FHZ1 P01581 P11345 P21708 P63086 Q62689	Erk1 Erk2 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Raf Raf1	Rattus norvegicus (Norway rat)
Estrogen-stimulated signaling through PRKCZ	3-phosphoinositide-dependent protein kinase 1 GTPase HRas GTPase KRas GTPase NRas Mitogen-activated protein kinase 1 Protein kinase C zeta type	O55173 P08644 P09217 P20171 P63086 Q04970	Erk2 Hras Hras1 Kras Kras2 Mapk Mapk1 Nras Pdk1 Pdpk1 Pkcz Prkcz Prkm1	Rattus norvegicus (Norway rat)
MAPK1 (ERK2) activation	Dual specificity mitogen-activated protein kinase kinase 2 Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Mitogen-activated protein kinase 1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A8I6AM23 D3ZD03 P20607 P22273 P36506 P40190 P41499 P63086 Q62689	Erk2 Il-6 Il6 Il6r Il6ra Il6st Jak1 Jak2 Map2k2 Mapk Mapk1 Mek2 Mkk2 Prkm1 Prkmk2 Ptpn11 Tyk2	Rattus norvegicus (Norway rat)
Insulin processing	Endoplasmic reticulum oxidoreductase 1 beta Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 Insulin-1 Protein disulfide-isomerase Proton-coupled zinc antiporter SLC30A8 Zinc transporter	A0A0G2K2V5 A0A8I6A3H1 D3ZY54 O54921 O54922 O54923 O54924 P01322 P04785 P0CE46 P97878 Q62824 Q62825	Ero1b Exo70 Exo84 Exoc1 Exoc2 Exoc3 Exoc4 Exoc5 Exoc6 Exoc7 Exoc8 Ins-1 Ins1 P4hb Pdia1 Sec10l1 Sec15 Sec15a Sec15l1 Sec5 Sec5l1 Sec6 Sec6l1 Sec8 Sec8l1 Slc30a5 Slc30a8 Znt8	Rattus norvegicus (Norway rat)
Tight junction interactions	Junctional adhesion molecule A Par-6 family cell polarity regulator beta Par-6 family cell polarity regulator gamma Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Protein kinase C iota type	D4A2F2 E9PT71 F1M7Y5 Q6B4M5 Q9JHY1 Q9Z340	F11r Jam1 Par-6a Par3 Par6a Pard3 Pard6a Pard6b Pard6g Pkcl Prkci	Rattus norvegicus (Norway rat)
Platelet Aggregation (Plug Formation)	Glycoprotein 9 Glycoprotein Ib platelet subunit alpha Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin	D3ZQU7 O08770 P18292 Q4AEG0 Q9JJM7	F2 Gp1ba Gp1bb Gp5 Gp9	Rattus norvegicus (Norway rat)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2 protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	B2RYN1 D3ZEB1 D3ZZU8 Q3KR92 Q5RJS8 Q9WVM4	F8 Fn3k Fn3krp Icmt Tpst1 Tpst2	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho beta	A0A8I6B5D5 D3Z8T6 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P61149 P63076 Q498D6 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Klb Plcg1	Rattus norvegicus (Norway rat)
FGFR4 ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSQ8 O54769 O88182 P13109 P36364 P61149 P63076 Q498D6 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4	Rattus norvegicus (Norway rat)
betaKlotho-mediated ligand binding	Fibroblast growth factor receptor 4 Fibroblast growth factor Klotho beta	D3Z8T6 Q498D6 Q8VI81	FGF15 Fgf19 Fgf8a Fgfr4 Klb	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSG7 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P48807 P61149 P63076 P70492 Q02195 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-7 Fgf-9 Fgf1 Fgf10 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2 Kgf Plcg1	Rattus norvegicus (Norway rat)
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Klotho Leucine-rich repeat transmembrane protein FLRT2 Leucine-rich repeat transmembrane protein FLRT3	A0A8I6B5D5 B1H234 D3ZTV3 D4AC39 F1LSQ8 P13109 P36364 P48807 P61149 P63076 P70492 Q04589 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Flrt1 Flrt2 Flrt3 Kl	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A8I6B5D5 F1LSQ8 P10686 P13109 P36364 P48807 P61149 P63076 P70492 Q04589 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Kl Plcg1	Rattus norvegicus (Norway rat)
FGFR2b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 7 Fibroblast growth factor binding protein 3 Fibroblast growth factor receptor Fibroblast growth factor-binding protein 1 Fibroblast growth factor Fibroblast growth factor	D3ZVI0 F1LSG7 P13109 P61149 P70492 Q02195 Q8R5L9 Q8VI79 Q9QY10	FGF22 Fgf-1 Fgf-2 Fgf-7 Fgf1 Fgf10 Fgf2 Fgf22 Fgf3 Fgf5c Fgf5d Fgf7 Fgfa Fgfbp1 Fgfbp3 Fgfr2 Kgf	Rattus norvegicus (Norway rat)
FGFR1b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	P13109 P26342 P61149 P70492 Q04589 Q8R5L9 Q8VI79 Q9Z254	FGF22 Fgf-1 Fgf-2 Fgf1 Fgf10 Fgf2 Fgf22 Fgf3 Fgf5c Fgf5d Fgfa Fgfr1 Flg Gipc Gipc1 Rgs19ip1 Tgfbr3	Rattus norvegicus (Norway rat)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor-like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Sprouty-related, EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2	A0A8I6A4X6 A0A8I6B5D5 F1LSQ8 O88182 P13109 P48807 P63076 P70492 Q3C2P8 Q7TQM3 Q8R5L9 Q8VI79 Q8VI82	FGF22 Fgf-2 Fgf-5 Fgf10 Fgf17 Fgf18 Fgf2 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf7a Fgf8 Fgfrl1 Spred1 Spred2	Rattus norvegicus (Norway rat)
FGFR2c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSG7 F1LSQ8 O54769 O88182 P13109 P36364 P48807 P61149 P63076 Q8R5L5 Q8VI82 Q9EST9	FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2	Rattus norvegicus (Norway rat)
FGFR1c ligand binding and activation	Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	A0A8I6B5D5 F1LSQ8 P13109 P26342 P36364 P48807 P61149 P63076 Q04589 Q8R5L5 Q8VI82 Q9EST9 Q9Z254	FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf17 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Gipc Gipc1 Rgs19ip1 Tgfbr3	Rattus norvegicus (Norway rat)
Interleukin-2 signaling	Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Protein-tyrosine kinase 2-beta Proto-oncogene tyrosine-protein kinase LCK SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase SYK Tyrosine-protein kinase	A0A8I6AM23 P17108 P26896 P26897 P52632 P70600 Q01621 Q5M824 Q62771 Q63272 Q64725	Fak2 Il-2 Il2 Il2ra Il2rb Jak1 Jak3 Lck Mgf Ptk2b Pyk2 Shc1 Stat5a Stat5b Syk	Rattus norvegicus (Norway rat)
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	FERM, ARH/RhoGEF and pleckstrin domain protein 2 Neuropilin-1 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Plexin A1 Plexin A2 Plexin A4 Plexin-A3 Semaphorin-3A Talin 1 Tyrosine-protein kinase Fyn	A0A8I6ABG6 A0A8I6AGW9 D3ZES7 D3ZFK8 D3ZPX4 D3ZWP6 Q5I6B8 Q62844 Q63548 Q9QWJ9	Farp2 Fyn Nrp1 Pip5k1c Plxna1 Plxna2 Plxna3 Plxna4 Plxna4a Sema3a Tln1	Rattus norvegicus (Norway rat)
GDP-fucose biosynthesis	Fucose kinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A0G2JVI4 A0A0G2K0C0 A0A8I5ZPV8 D3ZWW0 D4ACG8 G3V762	Fcsk Fpgt Fuk Fuom Gfus Gmds Slc35c1 Tsta3	Rattus norvegicus (Norway rat)	G85196CF G96881BQ
Sema3A PAK dependent Axon repulsion	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin A1 Plexin A2 Plexin A4 Plexin-A3 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase	A0A8I6AGW9 D3ZES7 D3ZPX4 D3ZWP6 D4A584 P34058 P35465 P53669 P82995 Q62829 Q62844 Q63548 Q64303 Q6RUV5 Q9QWJ9	Fes Fyn Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Limk Limk1 Nrp1 Pak1 Pak2 Pak3 Plxna1 Plxna2 Plxna3 Plxna4 Plxna4a Rac Rac1 Sema3a	Rattus norvegicus (Norway rat)
Free fatty acid receptors	Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3	B2GV46 Q76EI6 Q8K3T4	Ffar1 Ffar2 Ffar3 Gpr40 Gpr41 Gpr43	Rattus norvegicus (Norway rat)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha	A0A8J8XRQ3 O88302 O89040 P10687 P82471 Q8K3T4 Q99JE6 Q9JID2	Ffar1 Gna11 Gna14 Gna15 Gnaq Gpr40 Plcb1 Plcb2 Plcb3	Rattus norvegicus (Norway rat)

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