GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **901 - 925** of **1070** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Presynaptic function of Kainate receptors	Glutamate receptor ionotropic, kainate 3	P42264	Glur7 Grik3	Rattus norvegicus (Norway rat)
Synthesis of UDP-N-acetyl-glucosamine	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 N-acetyl-D-glucosamine kinase N-acetylglucosamine-6-phosphate deacetylase N-acylglucosamine 2-epimerase Phosphoacetylglucosamine mutase UDP-N-acetylglucosamine pyrophosphorylase 1	B2RYN0 D3ZF39 P51607 P81799 P82808 Q4KMC4 Q5BJY6	Amdhd2 Gfpt1 Gfpt2 Nagk Pgm3 Renbp Uap1	Rattus norvegicus (Norway rat)
Synthesis of 15-eicosatetraenoic acid derivatives	Glutathione peroxidase 1 Glutathione peroxidase 2 Phospholipid hydroperoxide glutathione peroxidase Polyunsaturated fatty acid lipoxygenase ALOX15 Polyunsaturated fatty acid lipoxygenase ALOX15B Prostaglandin G/H synthase 2	P04041 P35355 P36970 P83645 Q02759 Q8K4F2	Alox12l Alox15 Alox15b Cox-2 Cox2 Gpx1 Gpx2 Gpx4 Ptgs2	Rattus norvegicus (Norway rat)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin-like phospholipase domain containing 6	B0BND0 M0R715 Q9JL55	Enpp6 Gde1 Mir16 Pnpla6	Rattus norvegicus (Norway rat)
Platelet Aggregation (Plug Formation)	Glycoprotein 9 Glycoprotein Ib platelet subunit alpha Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin	D3ZQU7 O08770 P18292 Q4AEG0 Q9JJM7	F2 Gp1ba Gp1bb Gp5 Gp9	Rattus norvegicus (Norway rat)
Golgi Cisternae Pericentriolar Stack Reorganization	Golgi reassembly-stacking protein 1 Golgi reassembly-stacking protein 2 Golgin subfamily A member 2 Golgin-45 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-2A Serine/threonine-protein kinase PLK1	O35254 P05712 P10536 P21708 P63086 Q62673 Q62839 Q6AYB8 Q6NYB7 Q9R064	Blzf1 Erk1 Erk2 Golga2 Gorasp1 Gorasp2 Grasp65 Mapk Mapk1 Mapk3 Plk Plk1 Prkm1 Prkm3 Rab1 Rab1A Rab1b Rab2 Rab2a	Rattus norvegicus (Norway rat)
Signal attenuation	Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin-1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 F1MAL5 P01322 P0CE43 P15127 P21708 P35570 P62994 P63086 Q5M824	Ash Erk1 Erk2 Grb10 Grb2 Ins-1 Ins1 Insr Irs-1 Irs1 Irs2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Shc1 Sos1	Rattus norvegicus (Norway rat)
Insulin receptor signalling cascade	Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Insulin receptor Insulin-1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 P01322 P0CE43 P15127 P62994 Q5M824	Ash Grb10 Grb2 Ins-1 Ins1 Insr Shc1 Sos1	Rattus norvegicus (Norway rat)
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin-1	F1MAL5 P01322 P0CE43 P15127 P35570	Grb10 Ins-1 Ins1 Insr Irs-1 Irs1 Irs2	Rattus norvegicus (Norway rat)
SOS-mediated signalling	Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 F1MAL5 P35570 P62994	Ash Grb2 Irs-1 Irs1 Irs2 Sos1	Rattus norvegicus (Norway rat)
SHC-related events triggered by IGF1R	Growth factor receptor-bound protein 2 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 P01346 P08025 P24062 P62994 Q5M824	Ash Grb2 Igf-1 Igf-2 Igf1 Igf1r Igf2 Shc1 Sos1	Rattus norvegicus (Norway rat)
Interleukin-15 signaling	Growth factor receptor-bound protein 2 Interleukin 15 receptor subunit alpha Interleukin-15 Interleukin-2 receptor subunit beta SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase	A0A8I6AI14 A0A8I6AM23 D4A3T0 F1MAI3 P26896 P52631 P52632 P62994 P97604 Q5M824 Q62771 Q63272	Ash Grb2 Il15 Il15ra Il2rb Jak1 Jak3 Mgf Shc1 Sos1 Sos2 Stat3 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Signalling to RAS	Growth factor receptor-bound protein 2 SHC-transforming protein 1 SHC-transforming protein 2 SHC-transforming protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 O70142 O70143 P62994 Q5M824	Ash Grb2 Nshc Sck Shc1 Shc2 Shc3 Shcc Sos1	Rattus norvegicus (Norway rat)
GRB7 events in ERBB2 signaling	Growth factor receptor-bound protein 7 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3	O35569 P06494 P43322 Q62799 Q9QZC5	Erbb2 Erbb3 Grb7 Ndf Neu Nrg1 Nrg2 Ntak	Rattus norvegicus (Norway rat)
Growth hormone receptor signaling	Growth hormone receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Prolactin receptor Prolactin SH2B adapter protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein phosphatase non-receptor type 1	P01237 P01244 P05710 P16310 P20417 P21708 P52632 P63086 Q07014 Q62689 Q62771 Q62985	Erk1 Erk2 Gh Gh1 Ghr Jak2 Lyn Mapk Mapk1 Mapk3 Mgf Prkm1 Prkm3 Prl Prlr Ptpn1 Sh2-b Sh2b1 Sh2bpsm1 Stat5a Stat5b	Rattus norvegicus (Norway rat)
ADP signalling through P2Y purinoceptor 12	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma P2Y purinoceptor 12	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 P04897 P08753 P10824 P29348 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63219 Q9EPX4	Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnat-3 Gnat3 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 P2ry12 P2y12	Rattus norvegicus (Norway rat)
G-protein activation	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Mu-type opioid receptor Pro-opiomelanocortin Proenkephalin-B	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 A0A8J8XRQ3 D4AAI1 F2Z3T8 G3V8K2 O35353 O88302 P01194 P06300 P33535 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63219 P82471 Q9JID2	Gna11 Gna14 Gna15 Gnaq Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Oprm1 Pdyn Pomc Pomc2 Ror-b	Rattus norvegicus (Norway rat)
Sensory perception of sweet, bitter, and umami (glutamate) taste	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Inositol 1,4,5-trisphosphate receptor type 3 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 106 Taste receptor type 2 member 119 Taste receptor type 2 member 120 Taste receptor type 2 member 136 Taste receptor type 2 member 13 Taste receptor type 2 member 140 Taste receptor type 2 member 16 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 4 Taste receptor type 2 member 7	P29348 P52287 P54311 Q4VHE7 Q63269 Q675B7 Q67ER9 Q67ES0 Q67ET0 Q67ET1 Q67ET2 Q67ET3 Q67ET7 Q923K1 Q9JKE7 Q9JKE9 Q9JKT7 Q9JKU0 Q9JKU1 Q9Z0R7 Q9Z0R8	Gnat-3 Gnat3 Gnb1 Gnb3 Gpr70 Gpr71 Itpr3 T1r1 T1r2 T1r3 T2r16 T2r17 T2r18 T2r20 T2r38 Tas1r1 Tas1r2 Tas1r3 Tas2r1 Tas2r106 Tas2r108 Tas2r118 Tas2r119 Tas2r12 Tas2r120 Tas2r121 Tas2r126 Tas2r13 Tas2r130 Tas2r136 Tas2r137 Tas2r138 Tas2r139 Tas2r140 Tas2r144 Tas2r16 Tas2r18 Tas2r19 Tas2r26 Tas2r3 Tas2r31 Tas2r32 Tas2r38 Tas2r39 Tas2r4 Tas2r40 Tas2r41 Tas2r6 Tas2r7 Tr1 Tr2 Tr3	Rattus norvegicus (Norway rat)	G58161NS
Digestion	Guanylate cyclase activator 2B Guanylin Guanylyl cyclase C Intestinal-type alkaline phosphatase 1 Pirin	P15693 P23897 P28902 P70668 Q5M827	Alpi Guc2c Guca2 Guca2a Guca2b Gucy2c Pir	Rattus norvegicus (Norway rat)
MET Receptor Activation	HGF activator Hepatocyte growth factor receptor Hepatocyte growth factor Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type, 2 Serine protease hepsin	F7ELL4 G3V8S0 P17945 P97523 Q05511 Q4V8Q2	Hgf Hgfac Hpn Met Spint1 Spint2	Rattus norvegicus (Norway rat)
Inhibition of TSC complex formation by PKB	Hamartin RAC-beta serine/threonine-protein kinase Tuberin	P47197 P49816 Q9Z136	Akt2 Tsc1 Tsc2	Rattus norvegicus (Norway rat)
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral-signaling protein Mitochondrial import receptor subunit TOM70 TANK-binding kinase 1	D4A7D3 F7EXX5 P34058 P82995 Q66HG9 Q75Q39	Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Ips1 Irf3 Mavs Tbk1 Tomm70 Tomm70a Visa	Rattus norvegicus (Norway rat)
Sema3A PAK dependent Axon repulsion	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin A1 Plexin A2 Plexin A4 Plexin-A3 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase	A0A8I6AGW9 D3ZES7 D3ZPX4 D3ZWP6 D4A584 P34058 P35465 P53669 P82995 Q62829 Q62844 Q63548 Q64303 Q6RUV5 Q9QWJ9	Fes Fyn Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Limk Limk1 Nrp1 Pak1 Pak2 Pak3 Plxna1 Plxna2 Plxna3 Plxna4 Plxna4a Rac Rac1 Sema3a	Rattus norvegicus (Norway rat)
Drug-mediated inhibition of ERBB2 signaling	Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P06494 P82995 Q63692	Cdc37 Erbb2 Hsp86 Hsp90aa1 Hspca Neu	Rattus norvegicus (Norway rat)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor 7 PYD and CARD domain containing Pannexin-1 Proline-serine-threonine phosphatase-interacting protein 1 Protein SGT1 homolog Pyrin Thioredoxin-interacting protein Thioredoxin	B0BN85 B0BNK4 D4A523 G3V8L1 P11232 P34058 P60570 Q5M7W1 Q64663 Q9JJ25	Hsp84 Hsp90ab1 Hspc3 Hspcb Mefv Nlrp3 P2rx7 Panx1 Pstpip1 Px1 Pycard Sugt1 Txn Txn1 Txnip Vdup1	Rattus norvegicus (Norway rat)

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