GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism
Interleukin-2 signaling	Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Protein-tyrosine kinase 2-beta Proto-oncogene tyrosine-protein kinase LCK SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase SYK Tyrosine-protein kinase	A0A8I6AM23 P17108 P26896 P26897 P52632 P70600 Q01621 Q5M824 Q62771 Q63272 Q64725	Fak2 Il-2 Il2 Il2ra Il2rb Jak1 Jak3 Lck Mgf Ptk2b Pyk2 Shc1 Stat5a Stat5b Syk	Rattus norvegicus (Norway rat)
FGFR1c ligand binding and activation	Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	A0A8I6B5D5 F1LSQ8 P13109 P26342 P36364 P48807 P61149 P63076 Q04589 Q8R5L5 Q8VI82 Q9EST9 Q9Z254	FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf17 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Gipc Gipc1 Rgs19ip1 Tgfbr3	Rattus norvegicus (Norway rat)
FGFR2c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSG7 F1LSQ8 O54769 O88182 P13109 P36364 P48807 P61149 P63076 Q8R5L5 Q8VI82 Q9EST9	FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2	Rattus norvegicus (Norway rat)
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor-like 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Sprouty-related, EVH1 domain containing 1 Sprouty-related, EVH1 domain-containing protein 2	A0A8I6A4X6 A0A8I6B5D5 F1LSQ8 O88182 P13109 P48807 P63076 P70492 Q3C2P8 Q7TQM3 Q8R5L9 Q8VI79 Q8VI82	FGF22 Fgf-2 Fgf-5 Fgf10 Fgf17 Fgf18 Fgf2 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf7a Fgf8 Fgfrl1 Spred1 Spred2	Rattus norvegicus (Norway rat)
FGFR1b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor PDZ domain-containing protein GIPC1 Transforming growth factor beta receptor type 3	P13109 P26342 P61149 P70492 Q04589 Q8R5L9 Q8VI79 Q9Z254	FGF22 Fgf-1 Fgf-2 Fgf1 Fgf10 Fgf2 Fgf22 Fgf3 Fgf5c Fgf5d Fgfa Fgfr1 Flg Gipc Gipc1 Rgs19ip1 Tgfbr3	Rattus norvegicus (Norway rat)
FGFR2b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 7 Fibroblast growth factor binding protein 3 Fibroblast growth factor receptor Fibroblast growth factor-binding protein 1 Fibroblast growth factor Fibroblast growth factor	D3ZVI0 F1LSG7 P13109 P61149 P70492 Q02195 Q8R5L9 Q8VI79 Q9QY10	FGF22 Fgf-1 Fgf-2 Fgf-7 Fgf1 Fgf10 Fgf2 Fgf22 Fgf3 Fgf5c Fgf5d Fgf7 Fgfa Fgfbp1 Fgfbp3 Fgfr2 Kgf	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A8I6B5D5 F1LSQ8 P10686 P13109 P36364 P48807 P61149 P63076 P70492 Q04589 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Kl Plcg1	Rattus norvegicus (Norway rat)
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Klotho Leucine-rich repeat transmembrane protein FLRT2 Leucine-rich repeat transmembrane protein FLRT3	A0A8I6B5D5 B1H234 D3ZTV3 D4AC39 F1LSQ8 P13109 P36364 P48807 P61149 P63076 P70492 Q04589 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Flrt1 Flrt2 Flrt3 Kl	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSG7 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P48807 P61149 P63076 P70492 Q02195 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-7 Fgf-9 Fgf1 Fgf10 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2 Kgf Plcg1	Rattus norvegicus (Norway rat)
betaKlotho-mediated ligand binding	Fibroblast growth factor receptor 4 Fibroblast growth factor Klotho beta	D3Z8T6 Q498D6 Q8VI81	FGF15 Fgf19 Fgf8a Fgfr4 Klb	Rattus norvegicus (Norway rat)
FGFR4 ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSQ8 O54769 O88182 P13109 P36364 P61149 P63076 Q498D6 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho beta	A0A8I6B5D5 D3Z8T6 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P61149 P63076 Q498D6 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Klb Plcg1	Rattus norvegicus (Norway rat)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2 protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	B2RYN1 D3ZEB1 D3ZZU8 Q3KR92 Q5RJS8 Q9WVM4	F8 Fn3k Fn3krp Icmt Tpst1 Tpst2	Rattus norvegicus (Norway rat)
Platelet Aggregation (Plug Formation)	Glycoprotein 9 Glycoprotein Ib platelet subunit alpha Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin	D3ZQU7 O08770 P18292 Q4AEG0 Q9JJM7	F2 Gp1ba Gp1bb Gp5 Gp9	Rattus norvegicus (Norway rat)
Tight junction interactions	Junctional adhesion molecule A Par-6 family cell polarity regulator beta Par-6 family cell polarity regulator gamma Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Protein kinase C iota type	D4A2F2 E9PT71 F1M7Y5 Q6B4M5 Q9JHY1 Q9Z340	F11r Jam1 Par-6a Par3 Par6a Pard3 Pard6a Pard6b Pard6g Pkcl Prkci	Rattus norvegicus (Norway rat)
Insulin processing	Endoplasmic reticulum oxidoreductase 1 beta Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 Insulin-1 Protein disulfide-isomerase Proton-coupled zinc antiporter SLC30A8 Zinc transporter	A0A0G2K2V5 A0A8I6A3H1 D3ZY54 O54921 O54922 O54923 O54924 P01322 P04785 P0CE46 P97878 Q62824 Q62825	Ero1b Exo70 Exo84 Exoc1 Exoc2 Exoc3 Exoc4 Exoc5 Exoc6 Exoc7 Exoc8 Ins-1 Ins1 P4hb Pdia1 Sec10l1 Sec15 Sec15a Sec15l1 Sec5 Sec5l1 Sec6 Sec6l1 Sec8 Sec8l1 Slc30a5 Slc30a8 Znt8	Rattus norvegicus (Norway rat)
MAPK1 (ERK2) activation	Dual specificity mitogen-activated protein kinase kinase 2 Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Mitogen-activated protein kinase 1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A8I6AM23 D3ZD03 P20607 P22273 P36506 P40190 P41499 P63086 Q62689	Erk2 Il-6 Il6 Il6r Il6ra Il6st Jak1 Jak2 Map2k2 Mapk Mapk1 Mek2 Mkk2 Prkm1 Prkmk2 Ptpn11 Tyk2	Rattus norvegicus (Norway rat)
Estrogen-stimulated signaling through PRKCZ	3-phosphoinositide-dependent protein kinase 1 GTPase HRas GTPase KRas GTPase NRas Mitogen-activated protein kinase 1 Protein kinase C zeta type	O55173 P08644 P09217 P20171 P63086 Q04970	Erk2 Hras Hras1 Kras Kras2 Mapk Mapk1 Nras Pdk1 Pdpk1 Pkcz Prkcz Prkm1	Rattus norvegicus (Norway rat)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A8I6AM23 D4A109 F7FHZ1 P01581 P11345 P21708 P63086 Q62689	Erk1 Erk2 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Raf Raf1	Rattus norvegicus (Norway rat)
Growth hormone receptor signaling	Growth hormone receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Prolactin receptor Prolactin SH2B adapter protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein phosphatase non-receptor type 1	P01237 P01244 P05710 P16310 P20417 P21708 P52632 P63086 Q07014 Q62689 Q62771 Q62985	Erk1 Erk2 Gh Gh1 Ghr Jak2 Lyn Mapk Mapk1 Mapk3 Mgf Prkm1 Prkm3 Prl Prlr Ptpn1 Sh2-b Sh2b1 Sh2bpsm1 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Signaling by NODAL	Forkhead box O3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	D3ZBQ1 O70436 O70437 P21708 P63086 P84025	Erk1 Erk2 Foxo3 Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Smad2 Smad3 Smad4	Rattus norvegicus (Norway rat)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Peptidyl-prolyl cis-trans isomerase FKBP4 Prostaglandin E synthase 3 Serine/threonine-protein phosphatase 5 peptidylprolyl isomerase	F7EYK0 P06211 P34058 P53042 P82995 P83868 Q62986 Q9QVC8	Erbeta Esr Esr1 Esr2 Estr Fkbp4 Fkbp5 Fkbp52 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Nr3a1 Nr3a2 Ppp5c Ptges3 Tebp	Rattus norvegicus (Norway rat)
GRB7 events in ERBB2 signaling	Growth factor receptor-bound protein 7 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3	O35569 P06494 P43322 Q62799 Q9QZC5	Erbb2 Erbb3 Grb7 Ndf Neu Nrg1 Nrg2 Ntak	Rattus norvegicus (Norway rat)
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	F1MAL5 Q07014 Q07303 Q62689	Epor Irs2 Jak2 Lyn	Rattus norvegicus (Norway rat)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5Y949 D3ZAL7 D3ZFJ0 D4A4I3 F1MAL5 P29676 Q07014 Q07303 Q62689 Q63787 Q9Z1L0	Epo Epor Gab1 Irs2 Jak2 Lyn Pik3ca Pik3cb Pik3cd Pik3cg Pik3r1 Pik3r5	Rattus norvegicus (Norway rat)

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