renal fibrosis

Summary
Definition
A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function.
Super Class
kidney disease
Disease Ontology
DOID:0050855
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 23 in total
Gene ID Gene Symbol Description Source
2844 GPR21 G protein-coupled receptor 21
3458 IFNG interferon gamma
3845 KRAS KRAS proto-oncogene, GTPase
3953 LEPR leptin receptor
4312 MMP1 matrix metallopeptidase 1
4318 MMP9 matrix metallopeptidase 9
5054 SERPINE1 serpin family E member 1
6778 STAT6 signal transducer and activator of transcription 6
6868 ADAM17 ADAM metallopeptidase domain 17
7097 TLR2 toll like receptor 2
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11491 Adam17 a disintegrin and metallopeptidase domain 17
11596 Ager advanced glycosylation end product-specific receptor
12759 Clu clusterin
13058 Cybb cytochrome b-245, beta polypeptide
13617 Ednra endothelin receptor type A
13805 Eng endoglin
15978 Ifng interferon gamma
16653 Kras Kirsten rat sarcoma viral oncogene homolog
16847 Lepr leptin receptor
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
83516 Ppargc1a PPARG coactivator 1 alpha
Displaying all 5 entries
Gene ID Gene Symbol Description Source
33005 Nep3 Neprilysin 3
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
43222 Tl Toll
43558 Tace tace
Displaying 1 entry
Gene ID Gene Symbol Description Source
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying all 8 entries
Gene ID Gene Symbol Description Source
173685 nep-11 Neprilysin-11
174787 nep-1 Neprilysin-1
175383 zmp-2 Matrix metalloproteinase-B
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
181041 adm-4 Disintegrin and metalloproteinase domain-containing protein 17 homolog

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024