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Standards Ontologies Notations
graft-versus-host disease

Summary
Synonym
  • GvHD
  • graft versus host disease
Definition
An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.
Super Class
immune system disease
Disease Ontology
DOID:0081267
Mondo Disease Ontology
MeSH
ORDO
OMIM
Related Genes
Displaying entries 21 - 30 of 33 in total
Gene ID Gene Symbol Description Source
3557 IL1RN interleukin 1 receptor antagonist
3558 IL2 interleukin 2
3586 IL10 interleukin 10
3588 IL10RB interleukin 10 receptor subunit beta
3718 JAK3 Janus kinase 3
4288 MKI67 marker of proliferation Ki-67
5155 PDGFB platelet derived growth factor subunit B
6402 SELL selectin L
7035 TFPI tissue factor pathway inhibitor
7157 TP53 tumor protein p53
Displaying entries 11 - 20 of 30 in total
Gene ID Gene Symbol Description Source
15234 Hgf hepatocyte growth factor
15481 Hspa8 heat shock protein 8
15978 Ifng interferon gamma
16153 Il10 interleukin 10
16155 Il10rb interleukin 10 receptor, beta
16175 Il1a interleukin 1 alpha
16181 Il1rn interleukin 1 receptor antagonist
16183 Il2 interleukin 2
17345 Mki67 antigen identified by monoclonal antibody Ki 67
18591 Pdgfb platelet derived growth factor, B polypeptide
Displaying entries 11 - 18 of 18 in total
Gene ID Gene Symbol Description Source
60582 Il1rn interleukin 1 receptor antagonist
65270 Abo3 histo-blood group ABO system transferase 3
83785 Vegfa vascular endothelial growth factor A
116562 Il2 interleukin 2
246097 Fas Fas cell surface death receptor
296504 Abo2 histo-blood group ABO system transferase 2
304966 Fcgr3a Fc gamma receptor 3A
100301568 Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
Displaying 1 entry
Gene ID Gene Symbol Description Source
41840 Hsc70-4 Heat shock protein 70 cognate 4
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
563897 gbgt1l5 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5
566487 gbgt1l2 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2
100005565 gbgt1l8 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8
100005704 gbgt1l9 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 9
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100497509 abo.4 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 Xenopus tropicalis (tropical clawed frog)
108698211 abo.2.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog Xenopus laevis (African clawed frog)
108698863 abo.4.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog Xenopus laevis (African clawed frog)
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024