adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 21 - 30 of 38 in total
Gene ID Gene Symbol Description Source
4638 MYLK myosin light chain kinase
4879 NPPB natriuretic peptide B
5054 SERPINE1 serpin family E member 1
5320 PLA2G2A phospholipase A2 group IIA
5328 PLAU plasminogen activator, urokinase
6439 SFTPB surfactant protein B
6440 SFTPC surfactant protein C
6441 SFTPD surfactant protein D
6648 SOD2 superoxide dismutase 2
6915 TBXA2R thromboxane A2 receptor
Displaying entries 31 - 36 of 36 in total
Gene ID Gene Symbol Description Source
54409 Ramp2 receptor (calcitonin) activity modifying protein 2
56532 Ripk3 receptor-interacting serine-threonine kinase 3
74069 Serpina3a serine (or cysteine) peptidase inhibitor, clade A, member 3A
238393 Serpina3f serine (or cysteine) peptidase inhibitor, clade A, member 3F
238395 Serpina3j serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J
271047 Serpina3b serine (or cysteine) peptidase inhibitor, clade A, member 3B
Displaying entries 11 - 20 of 24 in total
Gene ID Gene Symbol Description Source
25350 Sftpd surfactant protein D
25377 Ambp alpha-1-microglobulin/bikunin precursor
25464 Icam1 intercellular adhesion molecule 1
25608 Lep leptin
25625 Tnfrsf1a TNF receptor superfamily member 1A
25670 Il15 interleukin 15
54320 Pdpn podoplanin
58966 Ramp2 receptor activity modifying protein 2
60582 Il1rn interleukin 1 receptor antagonist
81687 Mmp9 matrix metallopeptidase 9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

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Last updated: December 9, 2024