osteoporosis

Summary
Definition
A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
Super Class
bone resorption disease
Disease Ontology
DOID:11476
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 44 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
367 AR androgen receptor
581 BAX BCL2 associated X, apoptosis regulator
650 BMP2 bone morphogenetic protein 2
796 CALCA calcitonin related polypeptide alpha
799 CALCR calcitonin receptor
1277 COL1A1 collagen type I alpha 1 chain
1278 COL1A2 collagen type I alpha 2 chain
1432 MAPK14 mitogen-activated protein kinase 14
1586 CYP17A1 cytochrome P450 family 17 subfamily A member 1
Displaying entries 21 - 30 of 38 in total
Gene ID Gene Symbol Description Source
16846 Lep leptin
16847 Lepr leptin receptor
16973 Lrp5 low density lipoprotein receptor-related protein 5
17395 Mmp9 matrix metallopeptidase 9
17869 Myc myelocytomatosis oncogene
18383 Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
18538 Pcna proliferating cell nuclear antigen
19219 Ptger4 prostaglandin E receptor 4 (subtype EP4)
20656 Sod2 superoxide dismutase 2, mitochondrial
21803 Tgfb1 transforming growth factor, beta 1
Displaying entries 21 - 27 of 27 in total
Gene ID Gene Symbol Description Source
60628 Cxcr4 C-X-C motif chemokine receptor 4
81687 Mmp9 matrix metallopeptidase 9
84023 Ptger4 prostaglandin E receptor 4
84352 Col1a2 collagen type I alpha 2 chain
116506 Calcr calcitonin receptor
117516 Tnfsf11 TNF superfamily member 11
156767 Tnfrsf1b TNF receptor superfamily member 1B
Displaying all 4 entries
Gene ID Gene Symbol Description Source
33432 dpp decapentaplegic
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
30686 myca MYC proto-oncogene, bHLH transcription factor a
393141 mycb MYC proto-oncogene, bHLH transcription factor b
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397873 bmp2.L bone morphogenetic protein 2 L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175942 pdfr-1 Calcitonin receptor-like protein 1
179068 dbl-1 Protein dbl-1
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
Displaying 1 entry
Gene ID Gene Symbol Description Source
856014 GLR1 glutathione-disulfide reductase GLR1

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