osteoporosis

Summary
Definition
A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
Super Class
bone resorption disease
Disease Ontology
DOID:11476
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 44 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
367 AR androgen receptor
581 BAX BCL2 associated X, apoptosis regulator
650 BMP2 bone morphogenetic protein 2
796 CALCA calcitonin related polypeptide alpha
799 CALCR calcitonin receptor
1277 COL1A1 collagen type I alpha 1 chain
1278 COL1A2 collagen type I alpha 2 chain
1432 MAPK14 mitogen-activated protein kinase 14
1586 CYP17A1 cytochrome P450 family 17 subfamily A member 1
Displaying entries 31 - 38 of 38 in total
Gene ID Gene Symbol Description Source
21934 Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator
21938 Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b
21943 Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11
26416 Mapk14 mitogen-activated protein kinase 14
102866 Pls3 plastin 3 (T-isoform)
105348 Golm1 golgi membrane protein 1
384783 Irs2 insulin receptor substrate 2
666279 Dspp dentin sialophosphoprotein
Displaying entries 11 - 20 of 27 in total
Gene ID Gene Symbol Description Source
25235 Ghr growth hormone receptor
25341 Tnfrsf11b TNF receptor superfamily member 11B
25467 Irs1 insulin receptor substrate 1
25608 Lep leptin
25718 Igf1r insulin-like growth factor 1 receptor
25737 Pcna proliferating cell nuclear antigen
29373 Bmp2 bone morphogenetic protein 2
29393 Col1a1 collagen type I alpha 1 chain
59086 Tgfb1 transforming growth factor, beta 1
60582 Il1rn interleukin 1 receptor antagonist
Displaying all 4 entries
Gene ID Gene Symbol Description Source
33432 dpp decapentaplegic
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
30686 myca MYC proto-oncogene, bHLH transcription factor a
393141 mycb MYC proto-oncogene, bHLH transcription factor b
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397873 bmp2.L bone morphogenetic protein 2 L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175942 pdfr-1 Calcitonin receptor-like protein 1
179068 dbl-1 Protein dbl-1
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
Displaying 1 entry
Gene ID Gene Symbol Description Source
856014 GLR1 glutathione-disulfide reductase GLR1

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Last updated: December 9, 2024