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Sjogren's syndrome
Summary
- Synonym
-
- Sicca syndrome
- Sjogren syndrome
- xerodermosteosis
- Definition
- An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
- Super Class
- autoimmune disease of exocrine system
External Links
- Disease Ontology
- DOID:12894
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3558 | IL2 | interleukin 2 | |
| 3559 | IL2RA | interleukin 2 receptor subunit alpha | |
| 3565 | IL4 | interleukin 4 | |
| 3569 | IL6 | interleukin 6 | |
| 3586 | IL10 | interleukin 10 | |
| 3596 | IL13 | interleukin 13 | |
| 4049 | LTA | lymphotoxin alpha | |
| 4314 | MMP3 | matrix metallopeptidase 3 | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4586 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12064 | Bdnf | brain derived neurotrophic factor | |
| 12380 | Cast | calpastatin | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 12774 | Ccr5 | C-C motif chemokine receptor 5 | |
| 12775 | Ccr7 | C-C motif chemokine receptor 7 | |
| 13076 | Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | |
| 14102 | Fas | Fas cell surface death receptor | |
| 14573 | Gdnf | glial cell line derived neurotrophic factor | |
| 14960 | H2-Aa | histocompatibility 2, class II antigen A, alpha | |
| 14961 | H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171999 | poml-2 | Arylesterase | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like | |
| 188252 | lev-9 | Protein lev-9 |
