neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 106 in total
Gene ID Gene Symbol Description Source
50 ACO2 aconitase 2
334 APLP2 amyloid beta precursor like protein 2
387 RHOA ras homolog family member A
388 RHOB ras homolog family member B
389 RHOC ras homolog family member C
847 CAT catalase
1778 DYNC1H1 dynein cytoplasmic 1 heavy chain 1
1855 DVL1 dishevelled segment polarity protein 1
1857 DVL3 dishevelled segment polarity protein 3
2011 MARK2 microtubule affinity regulating kinase 2
Displaying entries 1 - 10 of 73 in total
Gene ID Gene Symbol Description Source
11804 Aplp2 amyloid beta precursor-like protein 2
13424 Dync1h1 dynein cytoplasmic 1 heavy chain 1
13542 Dvl1 dishevelled segment polarity protein 1
13728 Mark2 MAP/microtubule affinity regulating kinase 2
13856 Epo erythropoietin
14473 Gc vitamin D binding protein
14799 Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1)
14800 Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2)
14802 Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4)
14807 Grik3 glutamate receptor, ionotropic, kainate 3
Displaying entries 1 - 10 of 33 in total
Gene ID Gene Symbol Description Source
24335 Epo erythropoietin
24408 Grin1 glutamate ionotropic receptor NMDA type subunit 1
24767 Scnn1b sodium channel epithelial 1 subunit beta
24768 Scnn1g sodium channel epithelial 1 subunit gamma
24849 Tpi1 triosephosphate isomerase 1
25122 Scnn1a sodium channel epithelial 1 subunit alpha
25550 Slc1a1 solute carrier family 1 member 1
25721 Got2 glutamic-oxaloacetic transaminase 2
29482 Slc1a2 solute carrier family 1 member 2
29483 Slc1a3 solute carrier family 1 member 3
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
38742 GluRIA Glutamate receptor IA
38895 Sarm Sterile alpha and Armadillo motif
39836 st scarlet
40665 Nmdar1 NMDA receptor 1
43582 Tpi Triose phosphate isomerase
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
437021 tspan36 tetraspanin 36
447803 pon1 paraoxonase 1
494492 slc17a6a solute carrier family 17 member 6a
560753 tpi1b triosephosphate isomerase 1b
563467 slc17a8 solute carrier family 17 member 8
791696 asic1a acid-sensing (proton-gated) ion channel 1a
100004455 epoa erythropoietin a
100006041 rhoab ras homolog gene family, member Ab
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
181035 deg-1 Degenerin deg-1
181166 pkc-2 Protein kinase C;Protein kinase C-like 2
181728 mec-4 Degenerin mec-4
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188744 glt-4 Amino acid transporter;Putative sodium-dependent excitatory amino acid transporter glt-4
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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