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Standards Ontologies Notations
asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 206 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
101 ADAM8 ADAM metallopeptidase domain 8
128 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
134 ADORA1 adenosine A1 receptor
135 ADORA2A adenosine A2a receptor
142 PARP1 poly(ADP-ribose) polymerase 1
154 ADRB2 adrenoceptor beta 2
177 AGER advanced glycosylation end-product specific receptor
185 AGTR1 angiotensin II receptor type 1
186 AGTR2 angiotensin II receptor type 2
Displaying entries 41 - 50 of 191 in total
Gene ID Gene Symbol Description Source
13849 Ephx1 epoxide hydrolase 1, microsomal
13861 Epx eosinophil peroxidase
13983 Esr2 estrogen receptor 2 (beta)
14061 F2 coagulation factor II
14063 F2rl1 F2R like trypsin receptor 1
14068 F7 coagulation factor VII
14102 Fas Fas cell surface death receptor
14125 Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide
14130 Fcgr2b Fc receptor, IgG, low affinity IIb
14131 Fcgr3 Fc receptor, IgG, low affinity III
Displaying entries 1 - 10 of 112 in total
Gene ID Gene Symbol Description Source
24180 Agtr1a angiotensin II receptor, type 1a
24182 Agtr2 angiotensin II receptor, type 2
24225 Bdnf brain-derived neurotrophic factor
24232 C3 complement C3
24255 Cftr CF transmembrane conductance regulator
24260 Chrm3 cholinergic receptor, muscarinic 3
24310 Ace angiotensin I converting enzyme
24464 Hp haptoglobin
24493 Il1a interleukin 1 alpha
24598 Nos1 nitric oxide synthase 1
Displaying entries 21 - 30 of 33 in total
Gene ID Gene Symbol Description Source
41286 TkR86C Tachykinin-like receptor at 86C
41549 Octbeta2R Octopamine beta2 receptor
42245 ChT Choline transporter
42795 VAChT Vesicular acetylcholine transporter
42803 Hmgcr HMG Coenzyme A reductase
42890 Orct2 Organic cation transporter 2
42891 Orct Organic cation transporter
43222 Tl Toll
43551 TkR99D Tachykinin-like receptor at 99D
44885 mys myospheroid
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
394082 slc18a3b solute carrier family 18 member 3b
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
436718 rhocb ras homolog family member Cb
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
399298 ntf3.L neurotrophin 3 L homeolog Xenopus laevis (African clawed frog)
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172841 45566 Organic cation transporter 1
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175504 pat-3 Integrin beta pat-3
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178118 trpa-1 Ion transport domain-containing protein;Transient receptor potential cation channel subfamily A member 1 homolog
178215 pgp-1 Multidrug resistance protein pgp-1
178274 cho-1 High-affinity choline transporter 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
850462 GIT1 Git1p
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
851977 CTS2 putative chitinase
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
854394 STE13 Ste13p
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
HP:0000006 Autosomal dominant inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024