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Standards Ontologies Notations
glioblastoma

Summary
Synonym
  • GBM
  • adult glioblastoma multiforme
  • glioblastoma multiforme
  • grade IV adult Astrocytic tumor
  • primary glioblastoma multiforme
  • spongioblastoma multiforme
Definition
A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Super Class
malignant astrocytoma
Disease Ontology
DOID:3068
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 51 - 54 of 54 in total
Gene ID Gene Symbol Description Source
57332 CBX8 chromobox 8
64123 ADGRL4 adhesion G protein-coupled receptor L4
64506 CPEB1 cytoplasmic polyadenylation element binding protein 1
259266 ASPM assembly factor for spindle microtubules
Displaying entries 21 - 30 of 38 in total
Gene ID Gene Symbol Description Source
18654 Pgf placental growth factor
19224 Ptgs1 prostaglandin-endoperoxide synthase 1
19225 Ptgs2 prostaglandin-endoperoxide synthase 2
19263 Ptprb protein tyrosine phosphatase receptor type B
20539 Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
20848 Stat3 signal transducer and activator of transcription 3
20850 Stat5a signal transducer and activator of transcription 5A
21923 Tnc tenascin C
22059 Trp53 transformation related protein 53
22589 Atrx ATRX, chromatin remodeler
Displaying entries 1 - 10 of 24 in total
Gene ID Gene Symbol Description Source
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24628 Pdgfb platelet derived growth factor subunit B
24629 Pdgfrb platelet derived growth factor receptor beta
24842 Tp53 tumor protein p53
25313 Egf epidermal growth factor
25425 Ctsh cathepsin H
25589 Kdr kinase insert domain receptor
25669 Cpe carboxypeptidase E
29414 Akt3 AKT serine/threonine kinase 3
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
Displaying entries 1 - 10 of 13 in total
Gene ID Gene Symbol Description Source
31792 Nrg Neuroglian
31926 Idgf4 Imaginal disc growth factor 4
32115 Ptp10D Protein tyrosine phosphatase 10D
33599 Shaw Shaker cognate w
34091 Spn28Dc Serpin 28Dc
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35717 tor torso
35846 Cirl Calcium-independent receptor for alpha-latrotoxin
Displaying 1 entry
Gene ID Gene Symbol Description Source
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source
180628 cht-1 putative endochitinase
180931 cpr-6 Cathepsin B-like cysteine proteinase 6
181684 cpd-2 Peptidase M14 carboxypeptidase A domain-containing protein
186632 ver-4 Tyrosine-protein kinase receptor ver-4
Displaying all 7 entries
Gene ID Gene Symbol Description Source
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
853313 PBS2 mitogen-activated protein kinase kinase PBS2
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3
856699 NPP2 nucleotide diphosphatase/phosphodiesterase NPP2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024