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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
pulmonary fibrosis
Summary
- Synonym
-
- Fibrosis of lung
- Definition
- An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
- Super Class
- interstitial lung disease
External Links
- Disease Ontology
- DOID:3770
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4312 | MMP1 | matrix metallopeptidase 1 | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4586 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | |
| 4780 | NFE2L2 | NFE2 like bZIP transcription factor 2 | |
| 4803 | NGF | nerve growth factor | |
| 4851 | NOTCH1 | notch receptor 1 | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 5156 | PDGFRA | platelet derived growth factor receptor alpha | |
| 5328 | PLAU | plasminogen activator, urokinase | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11421 | Ace | angiotensin I converting enzyme | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 11774 | Ap3b1 | adaptor-related protein complex 3, beta 1 subunit | |
| 12015 | Bad | BCL2-associated agonist of cell death | |
| 12061 | Bdkrb1 | bradykinin receptor, beta 1 | |
| 12064 | Bdnf | brain derived neurotrophic factor | |
| 12491 | Cd36 | CD36 molecule | |
| 12550 | Cdh1 | cadherin 1 | |
| 12654 | Chi3l1 | chitinase 3 like 1 | |
| 12671 | Chrm3 | cholinergic receptor, muscarinic 3, cardiac |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 89824 | Chi3l1 | chitinase 3 like 1 | |
| 114099 | Cysltr1 | cysteinyl leukotriene receptor 1 | |
| 114114 | Dnm1l | dynamin 1-like | |
| 116510 | Timp1 | TIMP metallopeptidase inhibitor 1 | |
| 116553 | Il13 | interleukin 13 | |
| 116630 | Csf2 | colony stimulating factor 2 | |
| 117029 | Ccr5 | C-C motif chemokine receptor 5 | |
| 117108 | B3gat1 | beta-1,3-glucuronyltransferase 1 | |
| 192155 | Sftpb | surfactant protein B | |
| 287287 | Il4 | interleukin 4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 37455 | Egfr | Epidermal growth factor receptor | |
| 37892 | mAChR-A | muscarinic Acetylcholine Receptor, A-type | |
| 38868 | Snmp2 | Sensory neuron membrane protein 2 | |
| 42514 | Snmp1 | Sensory neuron membrane protein 1 | |
| 43275 | Ser | Serrate | |
| 251900 | GlcAT-I | Glucuronyltransferase I |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30718 | notch1a | notch receptor 1a | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 386856 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | |
| 548607 | b3gat1a | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 100332644 | b3gat1b | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) | |
| 100037907 | b3gat1 | beta-1,3-glucuronyltransferase 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 174517 | sqv-8 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8 | |
| 175182 | ver-1 | Protein ver-1 | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 175781 | daf-4 | Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 | |
| 179962 | gar-3 | Muscarinic acetylcholine receptor gar-3 |
