macular degeneration

Summary
Synonym
  • Macular degeneration of retina
Definition
A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.
Super Class
retinal degeneration
Disease Ontology
DOID:4448
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
Related Genes
Displaying entries 1 - 10 of 37 in total
Gene ID Gene Symbol Description Source
24 ABCA4 ATP binding cassette subfamily A member 4
348 APOE apolipoprotein E
355 FAS Fas cell surface death receptor
572 BAD BCL2 associated agonist of cell death
581 BAX BCL2 associated X, apoptosis regulator
629 CFB complement factor B
652 BMP4 bone morphogenetic protein 4
710 SERPING1 serpin family G member 1
717 C2 complement C2
718 C3 complement C3
Displaying entries 31 - 32 of 32 in total
Gene ID Gene Symbol Description Source
214403 Cfhr4 complement factor H-related 4
216616 Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1
Displaying entries 11 - 20 of 20 in total
Gene ID Gene Symbol Description Source
64639 Bad BCL2-associated agonist of cell death
79126 Cfi complement factor I
81686 Mmp2 matrix metallopeptidase 2
81687 Mmp9 matrix metallopeptidase 9
83516 Ppargc1a PPARG coactivator 1 alpha
83571 Cdkn1b cyclin-dependent kinase inhibitor 1B
83619 Nfe2l2 NFE2 like bZIP transcription factor 2
84024 Pon1 paraoxonase 1
246097 Fas Fas cell surface death receptor
295703 Serping1 serpin family G member 1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
33432 dpp decapentaplegic
34091 Spn28Dc Serpin 28Dc
36232 Sod3 Superoxide dismutase 3
38868 Snmp2 Sensory neuron membrane protein 2
41840 Hsc70-4 Heat shock protein 70 cognate 4
42514 Snmp1 Sensory neuron membrane protein 1
43222 Tl Toll
Displaying all 2 entries
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
398002 prph2.S peripherin 2 (retinal degeneration, slow) S homeolog Xenopus laevis (African clawed frog)
399322 bmp4.S bone morphogenetic protein 4 S homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
187297 poml-1 PON (paraoxonase) and MEC-6 Like
Displaying all 2 entries
Gene ID Gene Symbol Description Source
852102 IZH1 PAQR-type receptor
856014 GLR1 glutathione-disulfide reductase GLR1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024