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frontotemporal dementia
Summary
- Synonym
-
- Wilhemsen-Lynch disease
- frontotemporal lobar degeneration
- multiple system tauopathy with presenile dementia
- pallidopontonigral degeneration
- Definition
- A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language.
- Super Class
- brain disease dementia
External Links
- Disease Ontology
- DOID:9255
- Mondo Disease Ontology
- MeSH
- UMLS
- ORDO
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P10636 | Microtubule-associated protein tau | |
| P28799 | Progranulin | |
| Q9UQN3 | Charged multivesicular body protein 2b |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q99NH8 | Triggering receptor expressed on myeloid cells 2 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000709 | Psychosis |
| HP:0000710 | Hyperorality |
| HP:0000718 | Aggressive behavior |
| HP:0000719 | Inappropriate behavior |
| HP:0000723 | Restrictive behavior |
| HP:0000733 | Motor stereotypy |
| HP:0000734 | Disinhibition |
| HP:0000737 | Irritability |
| HP:0000741 | Apathy |
| HP:0000757 | Lack of insight |
