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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
External Links
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 441 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
31 ACACA acetyl-CoA carboxylase alpha
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
43 ACHE acetylcholinesterase (Yt blood group)
47 ACLY ATP citrate lyase
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
155 ADRB3 adrenoceptor beta 3
Displaying entries 1 - 10 of 54 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
11651 Akt1 thymoma viral proto-oncogene 1
11652 Akt2 thymoma viral proto-oncogene 2
11677 Akr1b1 aldo-keto reductase family 1 member B
11815 Apod apolipoprotein D
12015 Bad BCL2-associated agonist of cell death
12494 Cd38 CD38 antigen
12654 Chi3l1 chitinase 3 like 1
12894 Cpt1a carnitine palmitoyltransferase 1a, liver
14377 G6pc1 glucose-6-phosphatase catalytic subunit 1
Displaying entries 41 - 50 of 50 in total
Gene ID Gene Symbol Description Source
85496 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
89824 Chi3l1 chitinase 3 like 1
113992 Ugt1a6 UDP glucuronosyltransferase family 1 member A6
154516 Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C
154968 Oga O-GlcNAcase
252917 Nr1d1 nuclear receptor subfamily 1, group D, member 1
297508 Nampt nicotinamide phosphoribosyltransferase
309513 Ppp1r3c protein phosphatase 1, regulatory subunit 3C
310615 Crtc2 CREB regulated transcription coactivator 2
362282 Pck1 phosphoenolpyruvate carboxykinase 1
Displaying entries 21 - 30 of 46 in total
Gene ID Gene Symbol Description Source
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
42518 Oga O-GlcNAcase
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
42620 PyK Pyruvate kinase
43183 Ald1 Aldolase 1
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
43223 Lerp lysosomal enzyme receptor protein
43708 Ugt35D1 UDP-glycosyltransferase family 35 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
560788 parp1 poly (ADP-ribose) polymerase 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
407879 ppp1cc protein phosphatase 1, catalytic subunit, gamma isozyme Xenopus tropicalis (tropical clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
Displaying all 8 entries
Gene ID Gene Symbol Description Source
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
175591 ugt-62 UDP-glucuronosyltransferase
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
176788 aldo-1 Fructose-bisphosphate aldolase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180628 cht-1 putative endochitinase
189173 W03G11.3 Putative alpha-L-fucosidase
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying entries 11 - 17 of 17 in total
Gene ID Gene Symbol Description Source
854529 PYK2 pyruvate kinase PYK2
854651 GUT2 glycerol-3-phosphate dehydrogenase
854942 OGG1 8-oxoguanine glycosylase OGG1
855009 GLO1 lactoylglutathione lyase GLO1
855480 ZWF1 glucose-6-phosphate dehydrogenase
856781 GIP2 Gip2p
856870 GLC7 type 1 serine/threonine-protein phosphatase catalytic subunit GLC7
Related Glycoprotein
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
2645 GCK glucokinase
6514 SLC2A2 solute carrier family 2 member 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024