type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 1 - 10 of 133 in total
Gene ID Gene Symbol Description Source
43 ACHE acetylcholinesterase (Yt blood group)
153 ADRB1 adrenoceptor beta 1
177 AGER advanced glycosylation end-product specific receptor
217 ALDH2 aldehyde dehydrogenase 2 family member
335 APOA1 apolipoprotein A1
336 APOA2 apolipoprotein A2
338 APOB apolipoprotein B
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
355 FAS Fas cell surface death receptor
Displaying entries 31 - 40 of 102 in total
Gene ID Gene Symbol Description Source
14103 Fasl Fas ligand
14378 G6pc2 glucose-6-phosphatase, catalytic, 2
14380 G6pd2 glucose-6-phosphate dehydrogenase 2
14381 G6pdx glucose-6-phosphate dehydrogenase X-linked
14473 Gc vitamin D binding protein
14600 Ghr growth hormone receptor
14960 H2-Aa histocompatibility 2, class II antigen A, alpha
14961 H2-Ab1 histocompatibility 2, class II antigen A, beta 1
14962 Cfb complement factor B
14969 H2-Eb1 histocompatibility 2, class II antigen E beta
Displaying entries 1 - 10 of 61 in total
Gene ID Gene Symbol Description Source
24221 Avp arginine vasopressin
24232 C3 complement C3
24310 Ace angiotensin I converting enzyme
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24464 Hp haptoglobin
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
Displaying entries 21 - 30 of 43 in total
Gene ID Gene Symbol Description Source
40079 Ugt316A1 UDP-glycosyltransferase family 316 member A1
40653 PEK pancreatic eIF-2alpha kinase
41334 Ugt35A1 UDP-glycosyltransferase family 35 member A1
41549 Octbeta2R Octopamine beta2 receptor
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
41625 Ace Acetylcholine esterase
42490 Mvl Malvolio
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
42679 wfs1 wolfram syndrome 1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 21 - 29 of 29 in total
Gene ID Gene Symbol Description Source
181178 gpx-5 Glutathione peroxidase
181334 pek-1 Eukaryotic translation initiation factor 2-alpha kinase pek-1
181706 ace-1 Acetylcholinesterase 1
182513 gpx-3 Glutathione peroxidase 3
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9
189173 W03G11.3 Putative alpha-L-fucosidase
190099 sqv-6 Xylosyltransferase sqv-6;protein xylosyltransferase
191766 smf-2 NRAMP-like transporter smf-2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.0

Last updated: December 9, 2024