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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 121 - 130 of 133 in total
Gene ID Gene Symbol Description Source
9415 FADS2 fatty acid desaturase 2
9451 EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3
11213 IRAK3 interleukin 1 receptor associated kinase 3
23274 CLEC16A C-type lectin domain containing 16A
29843 SENP1 SUMO specific peptidase 1
51083 GAL galanin and GMAP prepropeptide
54658 UGT1A1 UDP glucuronosyltransferase family 1 member A1
55937 APOM apolipoprotein M
57818 G6PC2 glucose-6-phosphatase catalytic subunit 2
64131 XYLT1 xylosyltransferase 1
Displaying entries 61 - 70 of 102 in total
Gene ID Gene Symbol Description Source
17967 Ncam1 neural cell adhesion molecule 1
18132 Notch4 notch 4
18173 Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
18609 Pdx1 pancreatic and duodenal homeobox 1
18646 Prf1 perforin 1 (pore forming protein)
18791 Plat plasminogen activator, tissue
18979 Pon1 paraoxonase 1
19276 Ptprn2 protein tyrosine phosphatase receptor type N polypeptide 2
19692 Reg1 regenerating islet-derived 1
20292 Ccl11 C-C motif chemokine ligand 11
Displaying entries 11 - 20 of 61 in total
Gene ID Gene Symbol Description Source
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24586 Ncam1 neural cell adhesion molecule 1
24714 Reg1a regenerating family member 1 alpha
24770 Ccl2 C-C motif chemokine ligand 2
24787 Sod2 superoxide dismutase 2
24825 Tf transferrin
24835 Tnf tumor necrosis factor
24861 Ugt1a1 UDP glucuronosyltransferase family 1 member A1
24925 Adrb1 adrenoceptor beta 1
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31364 Fas2 Fasciclin 2
31926 Idgf4 Imaginal disc growth factor 4
32974 Zw Zwischenferment
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35105 Ugt301D1 UDP-glycosyltransferase family 301 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024