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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
type 1 diabetes mellitus
Summary
- Synonym
-
- IDDM
- insulin-dependent diabetes mellitus
- type I diabetes mellitus
- Definition
- A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
- Super Class
- autoimmune disease of endocrine system diabetes mellitus
External Links
- Disease Ontology
- DOID:9744
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
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- 2386959
- 2663960
- 2680187
- 3038633
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- 3051907
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Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 356 | FASLG | Fas ligand | |
| 551 | AVP | arginine vasopressin | |
| 590 | BCHE | butyrylcholinesterase | |
| 629 | CFB | complement factor B | |
| 685 | BTC | betacellulin | |
| 718 | C3 | complement C3 | |
| 842 | CASP9 | caspase 9 | |
| 867 | CBL | Cbl proto-oncogene | |
| 929 | CD14 | CD14 molecule | |
| 940 | CD28 | CD28 molecule |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12223 | Btc | betacellulin, epidermal growth factor family member | |
| 12266 | C3 | complement component 3 | |
| 12371 | Casp9 | caspase 9 | |
| 12386 | Ctnna2 | catenin alpha 2 | |
| 12402 | Cbl | Casitas B-lineage lymphoma | |
| 12475 | Cd14 | CD14 antigen | |
| 12477 | Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | |
| 12487 | Cd28 | CD28 antigen | |
| 12494 | Cd38 | CD38 antigen | |
| 12504 | Cd4 | CD4 antigen |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25668 | Cd38 | CD38 molecule | |
| 25670 | Il15 | interleukin 15 | |
| 25692 | Plat | plasminogen activator, tissue type | |
| 25704 | Il2ra | interleukin 2 receptor subunit alpha | |
| 25712 | Ifng | interferon gamma | |
| 29259 | Sell | selectin L | |
| 29260 | Tlr4 | toll-like receptor 4 | |
| 29397 | Ccl11 | C-C motif chemokine ligand 11 | |
| 29473 | Aoc3 | amine oxidase, copper containing 3 | |
| 29535 | Pdx1 | pancreatic and duodenal homeobox 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31364 | Fas2 | Fasciclin 2 | |
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 32974 | Zw | Zwischenferment | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 35105 | Ugt301D1 | UDP-glycosyltransferase family 301 member D1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30262 | ins | preproinsulin | |
| 114549 | ache | acetylcholinesterase (Yt blood group) | |
| 406731 | ugt1ab | UDP glucuronosyltransferase 1 family a, b | |
| 447803 | pon1 | paraoxonase 1 | |
| 560951 | xylt1 | xylosyltransferase I | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 100384891 | ugt1a7 | UDP glucuronosyltransferase 1 family, polypeptide A7 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 397761 | ncam1.S | neural cell adhesion molecule 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 397762 | ncam1.L | neural cell adhesion molecule 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 444363 | xylt1.L | xylosyltransferase I L homeolog | Xenopus laevis (African clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 100135191 | ugt1a6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100145490 | xylt1 | xylosyltransferase I | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171905 | ace-2 | Carboxylic ester hydrolase | |
| 171999 | poml-2 | Arylesterase | |
| 172085 | ugt-26 | UDP-glucuronosyltransferase | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175076 | ace-3 | Carboxylic ester hydrolase | |
| 175591 | ugt-62 | UDP-glucuronosyltransferase | |
| 175807 | ida-1 | Receptor-type tyrosine-protein phosphatase-like ida-1 | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 |
