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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 51 - 60 of 133 in total
Gene ID Gene Symbol Description Source
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3240 HP haptoglobin
3250 HPR haptoglobin-related protein
3291 HSD11B2 hydroxysteroid 11-beta dehydrogenase 2
3383 ICAM1 intercellular adhesion molecule 1
3458 IFNG interferon gamma
3460 IFNGR2 interferon gamma receptor 2
3481 IGF2 insulin like growth factor 2
3482 IGF2R insulin like growth factor 2 receptor
3486 IGFBP3 insulin like growth factor binding protein 3
Displaying entries 11 - 20 of 102 in total
Gene ID Gene Symbol Description Source
12223 Btc betacellulin, epidermal growth factor family member
12266 C3 complement component 3
12371 Casp9 caspase 9
12386 Ctnna2 catenin alpha 2
12402 Cbl Casitas B-lineage lymphoma
12475 Cd14 CD14 antigen
12477 Ctla4 cytotoxic T-lymphocyte-associated protein 4
12487 Cd28 CD28 antigen
12494 Cd38 CD38 antigen
12504 Cd4 CD4 antigen
Displaying entries 1 - 10 of 61 in total
Gene ID Gene Symbol Description Source
24221 Avp arginine vasopressin
24232 C3 complement C3
24310 Ace angiotensin I converting enzyme
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24464 Hp haptoglobin
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31364 Fas2 Fasciclin 2
31926 Idgf4 Imaginal disc growth factor 4
32974 Zw Zwischenferment
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35105 Ugt301D1 UDP-glycosyltransferase family 301 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024