type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 1 - 10 of 133 in total
Gene ID Gene Symbol Description Source
43 ACHE acetylcholinesterase (Yt blood group)
153 ADRB1 adrenoceptor beta 1
177 AGER advanced glycosylation end-product specific receptor
217 ALDH2 aldehyde dehydrogenase 2 family member
335 APOA1 apolipoprotein A1
336 APOA2 apolipoprotein A2
338 APOB apolipoprotein B
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
355 FAS Fas cell surface death receptor
Displaying entries 21 - 30 of 102 in total
Gene ID Gene Symbol Description Source
12519 Cd80 CD80 antigen
12524 Cd86 CD86 antigen
12613 Cel carboxyl ester lipase
12654 Chi3l1 chitinase 3 like 1
12774 Ccr5 C-C motif chemokine receptor 5
12870 Cp ceruloplasmin
13649 Egfr epidermal growth factor receptor
13666 Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3
14068 F7 coagulation factor VII
14102 Fas Fas cell surface death receptor
Displaying entries 51 - 60 of 61 in total
Gene ID Gene Symbol Description Source
84349 Cd40lg CD40 ligand
89814 Tnfsf4 TNF superfamily member 4
89824 Chi3l1 chitinase 3 like 1
116510 Timp1 TIMP metallopeptidase inhibitor 1
116562 Il2 interleukin 2
116660 Ptprn protein tyrosine phosphatase, receptor type, N
117029 Ccr5 C-C motif chemokine receptor 5
246097 Fas Fas cell surface death receptor
260320 F7 coagulation factor VII
287287 Il4 interleukin 4
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31364 Fas2 Fasciclin 2
31926 Idgf4 Imaginal disc growth factor 4
32974 Zw Zwischenferment
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35105 Ugt301D1 UDP-glycosyltransferase family 301 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 11 - 12 of 12 in total
Gene ID Gene Symbol Description Source Organism
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
108703114 xylt1.S xylosyltransferase I S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase

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