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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
matrix metallopeptidase 15
Summary
- Gene Symbol
-
- Mmp15
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| O54732 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| endodermal cell differentiation | ||
| collagen catabolic process | ||
| extracellular matrix organization | ||
| response to estradiol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| membrane | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| zinc ion binding | ||
| metalloendopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- matrix metalloproteinase-15
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| collagen catabolic process |
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10283 | prostate cancer | |
| DOID:2671 | transitional cell carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 4324 | HGNC:7161 | HUMAN28649 | ||
| 35997 | FB:FBgn0033438 | |||
| 37949 | FB:FBgn0035049 | |||
| 175839 | WB:WBGene00006987 | |||
| 282887 | BOVIN10543 | |||
| 291848 | 10116_1:004f3d | RGD:1308937 | RATNO15050 | |
| 467988 | PANTR12487 | |||
| 548675 | Xenbase:XB-GENE-1014388 | |||
| 561041 | ZFIN:ZDB-GENE-070817-4 | |||
| 706523 | MACMU27472 |
