G01614ZM

Summary
GlyTouCan ID
G01614ZM
IUPAC Condensed
Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GalNAc(a1-
Motifs
Di-sialyl T antigen
Subsumption Level
Fully-defined saccharide
Monoisotopic Mass
965.33
3D Structures
GlycoShape
G01614ZM
Displaying 1 entry
Archetype α β
G30110UW
G01614ZM
G04267XF
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 5 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
R
G01614ZM
R
ST6GALNAC2 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC3 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
Displaying entries 1 - 5 of 6 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
R
G01614ZM
R
ST6GALNAC2 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G65562ZE
benzyl
G01614ZM
benzyl
ST6GALNAC3 CMP-Neu5Ac
G65562ZE
Ser/Thr
G01614ZM
Ser/Thr
KEGG BRITE Database
KEGG ID
Enzyme
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R05914
GlycoEpitope
Epitope ID
EP0023
GlycomeAtlas

Tissues in which this glycan is expressed are highlighted in yellow.

Danio rerio
Brain Gill Heart Intestine Intestine Liver Ovary Skin Testis
Literature
Tissue
  • brain
  • gill
  • heart
  • intestine
  • liver
  • skin gland
  • testis
Reference
Yamakawa N et al. Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns. Nat Commun. 2018;9(1):4647. Published 2018 Nov 7. doi:10.1038/s41467-018-06950-3
DOI
10.1038/s41467-018-06950-3
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
5s:n-acetyl
6b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
7s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(3+2)4d
4:4d(5+1)5n
5:1o(6+2)6d
6:6d(5+1)7n
WURCS
WURCS=2.0/3,4,3/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-3/a3-b1_a6-d2_b3-c2
Literature
Displaying entries 91 - 100 of 103 in total
PubMed ID Title First Author Publication Date Source
6619128 Structures of the O-glycosidically linked oligosaccharides of human IgD Mellis SJ 1983 Oct 10
  • GlyGen
  • PubChem
6684483 Study of the carbohydrate moiety of human serum sex hormone-binding globulin AVVAKUMOV G 1983 Oct 04
  • GlyGen
  • PubChem
6628386 Isolation and structural characterization of five major sialyloligosaccharides and a sialylglycopeptide from normal human urine Parkkinen J 1983 Nov 2
  • GlyGen
6190803 Primary structure of the oligosaccharide determinant of blood group Cad specificity Blanchard D 1983 Jun 25
  • GlyGen
  • PubChem
7107637 Structures of N-linked and O-linked oligosaccharides on proteoglycan monomer isolated from the Swarm rat chondrosarcoma Nilsson B 1982 Sep 25
  • GlyGen
6786888 Localization of the carbohydrate units in a human immunoglobulin light chain, protein Sm lambda Garver F A 1981-04
  • GlyGen
6780550 Structures of sialylated O-glycosidically and N-glycosidically linked oligosaccharides in a monoclonal immunoglobulin light chain Chandrasekaran E V 1981-02-25
  • GlyGen
6940143 Amino acid and carbohydrate structural variants of glycoprotein products (M-N glycoproteins) of the M-N allelic locus Blumenfeld OO 1981 Feb
  • GlyGen
7430095 Structures of the asparagine-linked sugar chains of glycophorin A Yoshima H 1980 Oct 25
  • GlyGen
  • PubChem
7391006 Oligosaccharides on proteoglycans from the swarm rat chondrosarcoma Lohmander LS 1980 Jul 10
  • GlyGen
PubAnnotation
Displaying all 4 entries
Title Authors Source Publication Date PubMed ID
Reduction in disialyl-T antigen levels in mice deficient for both St6galnac3 and St6galnac4 results in blood filling of lymph nodes.
  • Fuseya S
  • Izumi H
  • Hamano A
  • Murakami Y
  • Suzuki R
  • Koiwai R
  • Hayashi T
  • Kuno A
  • Takahashi S
  • Kudo T
Sci Rep 2023 Jun 29 37386100
Mammalian sialyltransferases allow efficient Escherichia coli-based production of mucin-type O-glycoproteins but can also transfer Kdo.
  • Sim L
  • Thompson N
  • Geissner A
  • Withers SG
  • Wakarchuk WW
Glycobiology 2022 Apr 21 34939113
Majority of alpha2,6-sialylated glycans in the adult mouse brain exist in O-glycans: SALSA-MS analysis for knockout mice of alpha2,6-sialyltransferase genes.
  • Ohmi Y
  • Nishikaze T
  • Kitaura Y
  • Ito T
  • Yamamoto S
  • Sugiyama F
  • Matsuyama M
  • Takahashi Y
  • Takeda A
  • Kawahara T
  • Okajima T
  • Furukawa K
  • Furukawa K
Glycobiology 2021 Jun 3 33242079
Potent glycan inhibitors of myelin-associated glycoprotein enhance axon outgrowth in vitro.
  • Vyas AA
  • Blixt O
  • Paulson JC
  • Schnaar RL
J Biol Chem 2005 Apr 22 15701648

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Acknowledgements

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