GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **499** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
VEGFA-VEGFR2 Pathway	BEN domain-containing protein Cell division control protein 42 homolog Discoidin domain-containing receptor tyrosine kinase B Heat shock protein 12.6 Heat shock protein Hsp-12.2 Heat shock protein Hsp-16.1/Hsp-16.11 Heat shock protein Hsp-16.41 Heat shock protein Hsp-16.48/Hsp-16.49 Heat shock protein hsp-16.2 Heat-shock protein 12.1 Inactive tyrosine-protein kinase kin-32 Integrin alpha pat-2 Integrin beta pat-3 MAP kinase-activated protein kinase mak-1 MAP kinase-activated protein kinase mak-2 Mitogen-activated protein kinase pmk-1 Mitogen-activated protein kinase pmk-2 Mitogen-activated protein kinase pmk-3 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein vav-1 Ras-like GTP-binding protein rhoA Ras-related protein ced-10 Rho-associated protein kinase let-502 SH2 domain-containing protein SH2 domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein SHSP domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Stress-induced protein 1 Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 Uncharacterized integrin beta-like protein C05D9.3 cAMP-dependent protein kinase catalytic subunit	A0A1I6CMA1 B0M0L8 G5EDP9 G5EE36 G5EE56 G5EE62 G5EE65 G5EF99 G5EFV1 G5EGQ3 H2KZU7 K8ESG0 O44514 P02513 P06581 P06582 P21137 P34328 P34446 P34696 P91267 P92199 Q03206 Q05062 Q17446 Q17850 Q19227 Q19228 Q20164 Q20363 Q20660 Q21046 Q21360 Q22038 Q27874 Q45FX5 Q8MXI4 Q93344 Q94125 Q95PX0 Q95XA9 Q95YD4 Q95ZV7 Q965G5 Q9GYK2 Q9U3L3 Q9XVQ7 Q9XX60 Q9XXC0	C05D9.3 C49C3.10 CELE_F08H9.3 CELE_F08H9.4 CELE_F11E6.8 CELE_F12F6.1 CELE_F13B12.6 CELE_F21F3.2 CELE_F59F5.3 CELE_Y106G6D.4 CELE_Y106G6E.1 CELE_Y51B9A.9 CELE_ZK1128.7 aap-1 age-1 cdc-42 ced-10 ddr-2 gap-3 gska-3 gskl-2 hsp-12.1 hsp-12.2 hsp-12.3 hsp-12.6 hsp-16 hsp-16.1 hsp-16.11 hsp-16.2 hsp-16.41 hsp-16.48 hsp-16.49 hsp-17 hsp-43 hsp12-2 hsp16-1a hsp16-1b hsp16-2 hsp16-41 hsp16-48 hsp16-48a hsp16-48b hsp16-49 kin-1 kin-32 kin-36 let-502 mak-1 mak-2 max-2 nck-1 pak-1 pat-2 pat-3 pmk-1 pmk-2 pmk-3 rac-1 rho-1 rhoa sip-1 src-1 svh-2 svh-4 vav-1	Caenorhabditis elegans
TWIK related potassium channel (TREK)	Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein TWiK family of potassium channels protein 18 Uncharacterized protein B0310.1	G5EBQ2 G5EG92 G5EGD4 H2KZ66 O45422 O45891 O45894 Q10937 Q18120 Q21467 Q22042 Q22043 Q23297 Q65XY3 Q6BES3 Q6EUT8 Q9BL31 Q9XTV6 U4PFA8	B0310.1 twk-1 twk-11 twk-18 twk-21 twk-22 twk-24 twk-25 twk-26 twk-31 twk-33 twk-34 twk-35 twk-36 twk-42 twk-44 twk-45 twk-49 twk-8	Caenorhabditis elegans
G-protein activation	G protein gamma domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma Neuropeptide receptor 18 Probable G-protein coupled receptor C06G4.5	A0A0K3AXD3 A0A3B1DQQ4 G5ECT6 G5EGU1 P17343 P34311 P54406 Q09502 Q20636 Q20841 Q23033 Q9N452	C06G4.5 eat-11 egl-30 gbp-2 gpb-1 gpb-2 gpc-1 gpc-2 npr-16 npr-18 npr-23 npr-24 npr-26 npr-28	Caenorhabditis elegans
Formation of RNA Pol II elongation complex	BSD domain-containing protein CDK-activating kinase assembly factor MAT1 Cell division cycle protein 73 Cyclin-T1.1 Cyclin-T1.2 Cyclin-dependent kinase 7 Cyclin-like domain-containing protein DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Ell-associated factor Eaf Elongin-C FACT complex subunit SSRP1-A FACT complex subunit spt-16 General transcription and DNA repair factor IIH helicase subunit XPB General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIF subunit 2 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 IWS1-like protein OCEL domain-containing protein Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable cyclin-dependent kinase 9 Putative transcription elongation factor S-II RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II transcription factor SIII p18 subunit RNA polymerase II-associated factor 1 homolog RNA polymerase Rpb4/RPC9 core domain-containing protein RNA polymerase-associated protein CTR9 RNA polymerase-associated protein LEO1 Suppressor of Ty 6 homolog Transcription elongation factor B polypeptide 3 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha WD_REPEATS_REGION domain-containing protein	A5Z2V7 G5ECR7 G5EFV5 K8F7X5 O02092 O17245 O17869 O44499 P16356 P34424 P34425 P34567 P34703 P41848 P52652 P90783 Q03560 Q09413 Q09645 Q10578 Q17431 Q17558 Q17684 Q19375 Q19826 Q21338 Q8MYM8 Q93338 Q95PZ4 Q95QG8 Q965S0 Q9BKS1 Q9GR61 Q9N390 Q9N3C9 Q9N3L2 Q9N554 Q9N5K2 Q9N5R9 Q9N5U5 Q9TVL3 Q9TXQ9 Q9TZ93 Q9U3I0 Q9XVH6	3L686 CELE_F02E9.10 F13B12.1 T24H10.1 ama-1 ccnk-1 cdc-73 cdk-7 cdk-9 cit-1.1 cit-1.2 ctr-9 eaf-1 elb-1 elc-1 ell-1 emb-5 fcp-1 gtf-2F1 gtf-2F2 gtf-2H1 gtf-2H2C gtf-2H3 gtf-2H4 gtf-2H5 gtf-2f1 gtf-2f2 gtf-2h1 gtf-2h3 hmg-4 leo-1 mnat-1 pafo-1 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 spt-16 spt-4 spt-5 tceb-3 tpr-3 xpb-1 xpd-1	Caenorhabditis elegans
Organic anion transporters	Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial dicarboxylate carrier Mitochondrial glutamate carrier 1 Potential vesicular glutamate transporter vglu-3 Probable vesicular glutamate transporter eat-4 Putative tricarboxylate transport protein, mitochondrial SLC (SoLute Carrier) homolog Sodium-coupled monocarboxylate transporter 2 Sodium-dependent multivitamin transporter Uncharacterized transporter slc-17.2 Uncharacterized transporter slc-17.3	G5EE96 G5EEK1 H2KYN8 H2KZQ1 O01537 O17394 O44130 P34272 P34519 P34644 P90992 Q03567 Q10046 Q10048 Q20847 Q23514 Q23576 Q23616 Q8I4F6 Q93540	C38C10.2 CELE_F52H2.4 K11H3.3 cima-1 eat-4 misc-1 slc-17.1 slc-17.3 slc-17.4 slc-17.5 slc-17.6 slc-17.7 slc-17.8 slc-17.9 slc-25A18.1 slc-25A18.2 slc-25a10 slc-25a18.1 slc-25a18.2 slc-5A12 vglu-2 vglu-3	Caenorhabditis elegans
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Alpha-1,2-mannosyltransferase algn-9 Alpha-1,3/1,6-mannosyltransferase ALG2 Chitobiosyldiphosphodolichol beta-mannosyltransferase Dol-P-Man Dol-P-Man Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase Mannose-P-dolichol utilization defect 1 protein homolog N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase UDP-N-acetylglucosamine transferase subunit ALG14 homolog UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	E5QCI3 P52887 P54002 P92012 Q09226 Q19265 Q20157 Q22797 Q23361 Q9U1Z2 U4PE03	algn-1 algn-12 algn-13 algn-14 algn-2 algn-3 algn-6 algn-7 algn-8 algn-9 hpo-16 hpo-17 mpdu-1	Caenorhabditis elegans
Prostanoid ligand receptors	G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Neuropeptide receptor 18 Probable G-protein coupled receptor C06G4.5	A0A0K3AXD3 A0A3B1DQQ4 P34311 Q09502 Q20841 Q23033 Q9N452	C06G4.5 npr-16 npr-18 npr-23 npr-24 npr-26 npr-28	Caenorhabditis elegans
HSP90 chaperone cycle for SHRs	DNaJ domain (Prokaryotic heat shock protein) DNaJ domain (Prokaryotic heat shock protein) DUF148 domain-containing protein Heat shock protein 90 Heat shock protein hsp-1 Stress-induced-phosphoprotein 1	G5EC99 O16259 O16303 O45502 P09446 Q18688	CELE_F11F1.1 daf-21 dnj-12 dnj-19 hsp-1 hsp70a sti-1	Caenorhabditis elegans
alpha-linolenic acid (ALA) metabolism	ABC transporter domain-containing protein Acyl-coenzyme A oxidase acox-1.3 Delta(5) fatty acid desaturase fat-4 Delta(6)-fatty-acid desaturase fat-3 Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Long chain fatty acid elongase 1 Long chain fatty acid elongase 2 Long chain fatty acid elongase 5 Long chain fatty acid elongase 6 MaoC-like domain-containing protein Putative fatty acid elongase 3 Putative fatty acid elongase 4 palmitoyl-CoA hydrolase	F3Y5R4 G5EEE5 G5EG11 O45730 O62138 P49191 Q03574 Q19058 Q20300 Q20303 Q20904 Q23221 Q9BIA9 Q9NAC6 Q9XVQ9	C17C3.1 acox-1.3 acox-3 des-5 elo-1 elo-2 elo-3 elo-4 elo-5 elo-6 elo-7 elo-8 elo-9 fat-3 fat-4 maoc-1 pmp-4	Caenorhabditis elegans
Retinoid metabolism and transport	Beta,beta-carotene 9',10'-oxygenase Beta,beta-carotene 9',10'-oxygenase Carotenoid oxygenase Fatty acid-binding protein homolog 5 Fatty acid-binding protein homolog 6 Fatty acid-binding protein homolog 7 Fatty acid-binding protein homolog 8 LiPocalin-Related protein Lipase_GDSL domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Probable 5-hydroxyisourate hydrolase R09H10.3 Probable 5-hydroxyisourate hydrolase ZK697.8	G5EEB8 H2L060 O01812 O01814 O02323 O02324 O44578 P91020 P91997 P91998 Q17568 Q18903 Q21274 Q21882 Q22352 Q23320 Q9N2Z4 Q9NAI5 Q9TXT9 Q9U2E4 Q9U2J5	C01G5.5 C07D8.6 C56G3.2 CELE_F49E10.2 CELE_F53F1.2 CELE_F53F1.3 CELE_K07C5.2 CELE_Y39G8B.1 CELE_Y39G8B.2 CELE_Y65B4BR.1 CELE_ZC443.1 R09H10.3 ZK697.8 bcmo-1 bcmo-2 exc-15 lbp-5 lbp-6 lbp-7 lbp-8 lpr-2	Caenorhabditis elegans
HS-GAG biosynthesis	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 GlyPicaN Heparan sulfate 2-O-sulfotransferase hst-2 Heparan-sulfate 6-O-sulfotransferase Ig-like domain-containing protein InTestinal NeureXin-like LONg Laminin G domain-containing protein Probable syndecan Sulfotransferase domain-containing protein Sulfotransferase domain-containing protein Thioredoxin domain-containing protein Titin homolog UDP-sugar transporter sqv-7	C6KRM7 G4SLH0 G5ECV3 G5EFN7 G5EGU4 O17645 O45000 P50605 Q18530 Q18779 Q22574 Q4TTA0 Q966W3 Q9TZK5	C03H12.1 CELE_T19D12.6 gpn-1 hst-1 hst-2 hst-3.1 hst-3.2 hst-6 itx-1 lon-2 rig-5 sdn-1 sqv-7 ttn-1	Caenorhabditis elegans
VEGFR2 mediated cell proliferation	Protein kinase C-like 1 Protein kinase C-like 2 Protein kinase C-like 3 Sphingosine kinase 1 non-specific serine/threonine protein kinase	P34722 P90980 Q18425 Q19266 Q9UA62	CELE_W04B5.5 aPKC kin-11 pkc-2 pkc-3 sphk-1 tag-274 tpa-1	Caenorhabditis elegans
Synthesis of bile acids and bile salts	Cholesterol 25-hydroxylase-like protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein	A7DTF2 O01686 Q20027 Q93485	F35C8.5 obr-1 obr-2 obr-4	Caenorhabditis elegans
Downregulation of ERBB2 signaling	Cullin-5 E3 ubiquitin-protein ligase CHIP EGF-like domain-containing protein EGF-like domain-containing protein Heat shock protein 90 Polyubiquitin-A Probable Hsp90 co-chaperone cdc37 Protein kinase domain-containing protein Protein roller-3 Receptor tyrosine-protein kinase let-23 Tyrosine-protein kinase csk-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	G5ECJ6 G5ECY6 G5EFK8 O02108 O44191 P0CG71 P24348 P37165 P49632 Q18688 Q23639 Q8I7I5 Q9XX42	1G758 CELE_F14B4.1 CELE_Y38H6C.20 cdc-37 chn-1 csk-1 cul-5 daf-21 kin-7 let-23 rme-2 rol-3 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Glycerophospholipid catabolism	GP-PDE domain-containing protein Patatin-like phospholipase domain-containing protein ZK370.4 Putative patatin-like phospholipase domain-containing protein M110.7 glycerophosphocholine cholinephosphodiesterase	Q02331 Q21534 Q22129 Q9UAW8	CELE_T03G6.3 CELE_T12B3.3 M110.7 ZK370.4	Caenorhabditis elegans
Transport of RCbl within the body	Multidrug resistance-associated protein 1	Q3S1M2	mrp-1	Caenorhabditis elegans
Calmodulin induced events	EF-hand domain-containing protein G protein-coupled receptor kinase 2 Protein kinase C-like 1 Protein kinase C-like 2	P34722 P90980 Q09639 Q18136	cal-5 grk-2 kin-11 pkc-2 tpa-1	Caenorhabditis elegans
Ubiquitin-dependent degradation of Cyclin D	26S protease regulatory subunit 6A 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 G1/S-specific cyclin-D MPN domain-containing protein PCI domain-containing protein Polyubiquitin-A Probable 26S proteasome non-ATPase regulatory subunit 9 Probable 26S proteasome regulatory subunit 10B Probable 26S proteasome regulatory subunit 4 Probable 26S proteasome regulatory subunit 6B Probable 26S proteasome regulatory subunit rpn-6.1 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit pbs-5 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	O16368 O17071 O17586 O44156 O61742 O61792 O62102 O76371 O76577 P0CG71 P37165 P46502 P49632 P90868 P91477 Q04908 Q10920 Q17971 Q18115 Q18787 Q19324 Q20058 Q20585 Q20938 Q22253 Q23237 Q23449 Q27488 Q95005 Q95008 Q95PZ7 Q966I8 Q9GZH5 Q9N599 Q9U2M5 Q9XTT9 Q9XUV0	C14C10.5 CELE_F35G12.12 cyd-1 pas-1 pas-2 pas-3 pas-4 pas-5 pas-6 pbs-1 pbs-2 pbs-3 pbs-4 pbs-5 pbs-7 psmd-9 psme-3 rpn-1 rpn-10 rpn-11 rpn-12 rpn-2 rpn-3 rpn-5 rpn-6.1 rpn-7 rpn-8 rpn-9 rpt-1 rpt-2 rpt-3 rpt-4 rpt-5 rpt-6 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
TGF-beta receptor signaling activates SMADs	BMP-like protein unc-129 Cell surface receptor daf-1 Cell surface receptor daf-4 Dauer larva development regulatory growth factor daf-7 Dwarfin sma-4 E3 ubiquitin-protein ligase CBL FYVE-type domain-containing protein Furin-like protease kpc-1 Integrin alpha pat-2 Integrin beta pat-3 Nidogen Protein dbl-1 Smad protein daf-8 Uncharacterized integrin beta-like protein C05D9.3 peptidylprolyl isomerase peptidylprolyl isomerase	G5EBY8 G5EEL5 H2KZI9 O17798 P20792 P34446 P45897 P50488 P92172 Q19019 Q21733 Q27874 Q8I4E5 Q93791 Q9GYK2 Q9U2Q8	C05D9.3 aka-1 cem-3 cet-1 daf-1 daf-4 daf-7 daf-8 dbl-1 fkb-2 fkb-8 kpc-1 nid-1 pat-2 pat-3 sli-1 sma-4 unc-129	Caenorhabditis elegans
ERBB2 Activates PTK6 Signaling	EGF-like domain-containing protein EGF-like domain-containing protein Protein kinase domain-containing protein Protein nipi-4 Receptor tyrosine-protein kinase let-23 Tyrosine-protein kinase	A0A4V0IL59 G5EFK8 O16262 O44191 P24348 Q9N3S5	CELE_F14B4.1 CELE_Y47G6A.5 kin-7 let-23 nipi-4 rme-2 trk-1	Caenorhabditis elegans
Nephrin family interactions	Calponin-homology (CH) domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family SH2 domain-containing protein Synaptogenesis protein syg-1 Synaptogenesis protein syg-2 Tyrosine protein-kinase src-1	B1Q236 G5EE56 O17772 Q95PX0 Q95XA9 Q9U3P2	gap-3 nck-1 pes-7 src-1 syg-1 syg-2	Caenorhabditis elegans
Ca2+ pathway	Abnormal cell lineage protein 44 Beta-catenin-like protein hmp-2 Calcium/calmodulin-dependent protein kinase type II EF-hand domain-containing protein Frizzled-2 Frizzled-4 G protein gamma domain-containing protein Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma Protein Wnt-2 Protein mom-2 Protein mom-5 Protein phosphatase 2B regulatory subunit cnb-1 Protein pop-1 Ras protein let-60 Serine/threonine kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit	A0A0K3AWM6 G5ECQ2 G5ECT6 G5EDN6 G5EDV1 O44326 O62305 P17343 P22981 P34889 P51875 P54406 Q0G819 Q10459 Q10666 Q18136 Q20636 Q27886 Q9U9Y8	cal-5 cfz-2 cna-1 cnb-1 cwn-2 eat-11 gbp-2 goa-1 gpb-1 gpb-2 gpc-1 gpc-2 hmp-2 let-60 lin-17 lin-34 lin-44 lit-1 mom-2 mom-5 nlk pop-1 tax-6 unc-43 wnt-2	Caenorhabditis elegans
Scavenging of heme from plasma	MMP-like protein Matrix metalloproteinase-A Matrix metalloproteinase-B Matrix metalloproteinase-C Peptidase metallopeptidase domain-containing protein Uncharacterized protein	G5EBU3 G5ECC4 G5EGM1 O17913 O44836 Q21182	CELE_K03B8.6 zmp-1 zmp-2 zmp-3 zmp-5 zmp-6	Caenorhabditis elegans
Glyoxylate metabolism and glycine degradation	Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase D-amino-acid oxidase D-aspartate oxidase 1 D-aspartate oxidase 2 D-aspartate oxidase 3 FMN hydroxy acid dehydrogenase domain-containing protein Proline dehydrogenase 1, mitochondrial	B1GRK5 O01739 O02158 O45228 O45307 Q17994 Q19564 Q94055 Q95XG9	CELE_F41E6.5 CELE_T09B4.8 agxt-1 daao-1 ddo-1 ddo-2 ddo-3 got-2.2 prdh-1 prodh	Caenorhabditis elegans
Thyroxine biosynthesis	Dual oxidase 1 Iodotyrosine dehalogenase 1 homolog NAD(P)H oxidase (H2O2-forming) Peroxidasin homolog pxn-1 Peroxidasin homolog pxn-2 Sodium-coupled monocarboxylate transporter 2 Sodium-dependent multivitamin transporter	G5EG78 O01795 O17394 O61213 P34273 Q1ENI8 Q23616	CELE_F52H2.4 bli-3 duox-2 pxn-1 pxn-2 slc-5A12 sup-18	Caenorhabditis elegans

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