GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **499** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
PI-3K cascade:FGFR1	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein let-756 Sex muscle abnormal protein 5	G5EDP9 G5EEF1 P29355 Q10656 Q11184 Q18758 Q94125 Q9TZA0	aap-1 age-1 egl-15 egl-17 klo-1 klo-2 let-756 sem-5	Caenorhabditis elegans
PI-3K cascade:FGFR4	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein let-756 Sex muscle abnormal protein 5	G5EDP9 G5EEF1 P29355 Q10656 Q11184 Q18758 Q94125 Q9TZA0	aap-1 age-1 egl-15 egl-17 klo-1 klo-2 let-756 sem-5	Caenorhabditis elegans
PI3K events in ERBB2 signaling	EGF-like domain-containing protein EGF-like domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5	G5EDP9 G5EFK8 O44191 P24348 P29355 Q94125	CELE_F14B4.1 aap-1 age-1 kin-7 let-23 rme-2 sem-5	Caenorhabditis elegans
PI3K/AKT Signaling	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Kringle domain-containing protein Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Protein nipi-3 RICTOR_N domain-containing protein Ras-related protein Rab-18 Ras-related protein ced-10 Ras-related protein rac-2 Receptor tyrosine-protein kinase let-23 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Serine/threonine-protein kinase sgk-1 Sex muscle abnormal protein 5 Stress-activated map kinase-interacting protein 1 homolog Striatin N-terminal domain-containing protein Target of rapamycin complex subunit lst8 Target of rapamycin homolog Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2 non-specific serine/threonine protein kinase	A0A1I6CMA1 A0A486WY88 G5EDP9 G5EE56 G5EED4 G5EEF1 G5EFK8 G5EFN2 H2KZU7 O44191 P24348 P29355 P91040 P91823 Q03206 Q10656 Q11184 Q17941 Q18758 Q21046 Q2PJ68 Q94124 Q94125 Q95Q95 Q95ZV7 Q9BL44 Q9N413 Q9NA80 Q9TZA0 Q9UA62 Q9XTG7 Q9XVQ7	CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_T22A3.6 CELE_W04B5.5 CELE_Y71H2AM.12 CeTor aap-1 age-1 akt-1 akt-2 cash-1 ced-10 ddr-2 egl-15 egl-17 kin-36 kin-7 klo-1 klo-2 let-23 let-363 let-756 mlst-8 nipi-3 pvf-1 rac-1 rac-2 rict-1 rme-2 sem-5 sgk-1 sinh-1 src-1 svh-2 svh-4	Caenorhabditis elegans
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Discoidin domain-containing receptor tyrosine kinase B EGF-like domain-containing protein EGF-like domain-containing protein EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Kringle domain-containing protein Myoblast growth factor receptor egl-15 PIPK domain-containing protein PIPK domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Platelet-derived growth factor (PDGF) family profile domain-containing protein Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein Protein kinase domain-containing protein Protein kinase domain-containing protein Protein let-756 Ras-related protein Rab-18 Ras-related protein ced-10 Ras-related protein rac-2 Receptor tyrosine-protein kinase let-23 Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Sex muscle abnormal protein 5 Striatin N-terminal domain-containing protein Tyrosine protein-kinase src-1 Tyrosine-protein kinase receptor svh-2	A0A1I6CMA1 A0A486WY88 A9UJN4 G5EDP9 G5EE56 G5EEF1 G5EFK8 G5EGK8 H2KZU7 O01759 O18178 O44191 P24348 P29355 P91823 Q03206 Q09543 Q10656 Q11184 Q17941 Q18758 Q21046 Q94124 Q94125 Q95ZV7 Q9BL44 Q9BL73 Q9N413 Q9TZA0 Q9XTG7 Q9XVQ7	CELE_F11E6.8 CELE_F14B4.1 CELE_F59F5.3 CELE_T22A3.6 CELE_Y71H2AM.12 aap-1 age-1 akt-1 akt-2 cash-1 ced-10 ddr-2 egl-15 egl-17 kin-36 kin-7 klo-1 klo-2 let-23 let-756 let-92 paa-1 ppk-1 ppk-2 pptr-1 pptr-2 pvf-1 rac-1 rac-2 rme-2 sem-5 src-1 svh-2 svh-4	Caenorhabditis elegans
PKA-mediated phosphorylation of key metabolic factors	Protein WBSCR14 homolog	P41846	mio mml-1	Caenorhabditis elegans
PKR-mediated signaling	ATP-dependent RNA helicase A Cyclin-dependent kinase 1 DRBM domain-containing protein DRBM domain-containing protein DZF domain-containing protein DZF domain-containing protein Dual specificity mitogen-activated protein kinase kinase jkk-1 Dual specificity mitogen-activated protein kinase kinase mek-1 Dual specificity mitogen-activated protein kinase kinase sek-1 E3 ubiquitin-protein ligase ari-1.1 Eukaryotic translation initiation factor 2-alpha kinase pek-1 HECT domain-containing protein J domain-containing protein NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Polyubiquitin-A Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein kinase domain-containing protein STE20-related kinase adapter protein strd-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription b Sphingosine kinase 1 Ubiquitin-conjugating enzyme E2 ubc-18 Ubiquitin-like domain-containing protein X-linked retinitis pigmentosa GTPase regulator homolog mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase	D3YT30 E9RKC7 G5EBF5 G5ECN5 G5EDF7 G5EDT6 G5EGK8 O01965 O18178 O44820 O62349 P0CG71 P34556 P91189 Q09543 Q18425 Q19192 Q20977 Q21307 Q21633 Q22307 Q58AU7 Q58AU8 Q5DX34 Q8MPS3 Q95PX0 Q9BL11 Q9NAD6 Q9TYV7 Q9XWJ9	CELE_F52C6.3 CELE_R11H6.5 CELE_T12G3.2 ari-1.1 cdk-1 dnj-7 dus-2 glo-4 herc-1 jkk-1 let-92 mek-1 mek-5 ncc-1 nck-1 paa-1 pek-1 pptr-1 rde-4 rha-1 sek-1 sek-3 sek-4 sek-5 sphk-1 sta-1 sta-2 stat-b strd-1 tag-274 ubc-18 ubia ubq-1 zfr-1	Caenorhabditis elegans
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8 Guanine nucleotide-binding protein subunit alpha	G5EBH0 G5EGU1	egl-30 egl-8	Caenorhabditis elegans
PTK6 Down-Regulation	Protein kinase domain-containing protein Protein nipi-4 Tyrosine-protein kinase	A0A4V0IL59 O16262 Q9N3S5	CELE_Y47G6A.5 nipi-4 trk-1	Caenorhabditis elegans
PTK6 Regulates Proteins Involved in RNA Processing	Protein kinase domain-containing protein Protein nipi-4 RRM domain-containing protein Tyrosine-protein kinase	A0A4V0IL59 B3GWA1 O16262 Q9N3S5	CELE_Y47G6A.5 nipi-4 nono-1 trk-1	Caenorhabditis elegans
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	CED-5 Cell death abnormality protein 12 Cell death abnormality protein 2 Protein kinase domain-containing protein Protein nipi-4 Ras-like GTP-binding protein rhoA Ras-related protein ced-10 Rho-GAP domain-containing protein Tyrosine-protein kinase	A0A4V0IL59 G5EEN3 O16262 O45611 Q03206 Q22038 Q8STE5 Q9N3S5 Q9NHC3	CELE_Y47G6A.5 ced-10 ced-12 ced-2 ced-5 nipi-4 rac-1 rga-5 rho-1 rhoa trk-1	Caenorhabditis elegans
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	E3 ubiquitin-protein ligase CBL IRS-type PTB domain-containing protein Polyubiquitin-A Protein kinase domain-containing protein Protein nipi-4 Rho-GAP domain-containing protein Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2 Tyrosine-protein kinase Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A4V0IL59 E6N0V1 H2KZV4 O16262 P0CG71 P37165 P49632 Q17941 Q19019 Q9N3S5 Q9XTG7	CELE_F23H11.4 CELE_Y47G6A.5 akt-1 akt-2 nipi-4 rog-1 sli-1 trk-1 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating Carbohydrate kinase FGGY N-terminal domain-containing protein Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase-2 Probable-ribose 5-phosphate isomerase Putative 6-phosphogluconolactonase Putative deoxyribose-phosphate aldolase Ribokinase Ribulose-phosphate 3-epimerase Transaldolase transketolase	O17759 O18229 O45814 O45934 P41994 Q17761 Q19133 Q19264 Q27464 Q95ZW2 Q966C7	CELE_F07A11.5 CELE_F08F8.7 CELE_Y43F4B.5 F09E5.3 T25B9.9 Y57G11C.3 gspd-1 rpia-1 shpk-1 tald-1 tkt-1	Caenorhabditis elegans	G31080DL
Peptide ligand-binding receptors	G-protein coupled receptors family 1 profile domain-containing protein SERPIN domain-containing protein SERPIN domain-containing protein Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein	A9Z1L1 G5ECY2 G5EE40 G5EFH4 O17365 O18014 O45520 Q18287 Q19651 Q9XVQ1	C28G1.2 CELE_F15D3.4 CELE_F44G3.7 npr-25 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8	Caenorhabditis elegans
Peroxisomal protein import	2-hydroxyacyl-CoA lyase Acyl-coenzyme A oxidase acox-1.1 Acyl-coenzyme A oxidase acox-1.2 Acyl-coenzyme A oxidase acox-1.3 Acyl-coenzyme A oxidase acox-1.4 Acyl-coenzyme A oxidase acox-3 Acyl-coenzyme A oxidase Acyl-coenzyme A thioesterase 1-like Alanine--glyoxylate aminotransferase Alpha-methylacyl-CoA racemase Amine oxidase domain-containing protein BAAT/acyl-CoA thioester hydrolase protein BAAT/acyl-CoA thioester hydrolase protein BAAT_C domain-containing protein Catalase Choline/carnitine acyltransferase domain-containing protein Choline/carnitine acyltransferase domain-containing protein D-amino-acid oxidase D-aspartate oxidase 1 D-aspartate oxidase 2 D-aspartate oxidase 3 Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Enoyl-CoA Hydratase FMN hydroxy acid dehydrogenase domain-containing protein Glutathione s-transferase kappa 2 Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] Lon protease homolog 2, peroxisomal Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Malonyl-CoA decarboxylase, mitochondrial MaoC-like domain-containing protein Mpv17-like protein Peroxisomal coenzyme A diphosphatase ndx-8 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisome assembly protein 12 Polyubiquitin-A Probable acyl-coenzyme A oxidase acox-1.5 Putative nudix hydrolase 7 Putative sarcosine oxidase RING-type E3 ubiquitin transferase TPR_REGION domain-containing protein UBA domain-containing protein Ubiquitin-conjugating enzyme E2 2 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized protein B0272.4 hydroxymethylglutaryl-CoA lyase palmitoyl-CoA hydrolase	A0A486WVT5 B1GRK5 B3WFZ3 G5EFP8 G5EG81 G5EGA6 H9G2T4 O01739 O01862 O16249 O17761 O45003 O45307 O62137 O62138 O62139 O62140 O76383 P0CG71 P34355 P35129 P37165 P41942 P49632 P91148 Q17474 Q17499 Q18006 Q18122 Q18355 Q18426 Q18916 Q18973 Q19058 Q19189 Q19564 Q19878 Q19951 Q20048 Q20959 Q20992 Q7YWV6 Q8MYL7 Q93839 Q93930 Q94055 Q95XG9 Q95XN1 Q9BIA9 Q9GYN3 Q9NA25 Q9XW87	B0272.4 B0395.3 C15B12.1 C17C3.1 C24A3.4 C31H5.6 C32D5.11 CELE_F41E6.5 CELE_F44E7.4 CELE_F58A6.1 CELE_K05B2.4 CELE_T05E7.1 CELE_T20B3.1 CELE_T24B8.7 CELE_W03D8.8 CELE_Y71G12B.10 T18D3.9 acl-7 acox-1 acox-1.1 acox-1.2 acox-1.3 acox-1.4 acox-1.5 acox-1.6 acox-2 acox-3 acox-4 acox-5 acox-6 acs-20 acs-22 agxt-1 ctl-3 daao-1 dapat ddo-1 ddo-2 ddo-3 dhrs-4 ech-8 gstk-2 hacl-1 hpo-15 idh-1 let-70 lonp-2 maoc-1 mlcd-1 ndx-7 ndx-8 prx-12 prx-13 prx-14 prx-5 ubc-2 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Phase 0 - rapid depolarisation	Guanylate kinase/L-type calcium channel beta subunit domain-containing protein SH3 domain-containing protein STarGazin (Mammalian calcium channel) homolog STarGazin (Mammalian calcium channel) homolog Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent calcium channel unc-36	A0A078BQJ0 G5EBI8 G5EDT2 O01661 P34374 Q8MQA1	STG-1 ccb-1 ccb-2 egl-19 stg-1 stg-2 unc-36 unc-72	Caenorhabditis elegans
Phase 2 - plateau phase	Guanylate kinase/L-type calcium channel beta subunit domain-containing protein SH3 domain-containing protein STarGazin (Mammalian calcium channel) homolog STarGazin (Mammalian calcium channel) homolog Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent calcium channel unc-36	A0A078BQJ0 G5EBI8 G5EDT2 O01661 P34374 Q8MQA1	STG-1 ccb-1 ccb-2 egl-19 stg-1 stg-2 unc-36 unc-72	Caenorhabditis elegans
Phase 4 - resting membrane potential	IRK_C domain-containing protein Inward rectifier potassium channel irk-1 Inward rectifier potassium channel irk-1 Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein TWiK family of potassium channels protein 18 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Uncharacterized protein B0310.1	A0A1C3NSK2 A0A1C3NSN6 A1EHR5 F5GUD1 G5EBQ2 G5ECW6 G5EG92 G5EGD4 H2KZ66 O17185 O45422 O45891 O45894 P52192 Q10937 Q18120 Q21467 Q22042 Q22043 Q23297 Q65XY3 Q6BES3 Q6EUT8 Q9BL31 Q9NEV3 Q9XTV6 U4PFA8	B0310.1 irk-1 irk-2 irk-3 irk-4 sup-9 twk-1 twk-11 twk-14 twk-18 twk-20 twk-21 twk-22 twk-24 twk-25 twk-26 twk-31 twk-33 twk-34 twk-35 twk-36 twk-39 twk-42 twk-44 twk-45 twk-46 twk-49 twk-8	Caenorhabditis elegans
Phase I - Functionalization of compounds	3-ketosteroid oxygenase AB hydrolase-1 domain-containing protein Aldehyde dehydrogenase Aldehyde dehydrogenase Alpha/beta hydrolase fold-3 domain-containing protein CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family CYtochrome P450 family Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Cytochrome b5 heme-binding domain-containing protein Cytochrome b5 heme-binding domain-containing protein Epoxide hydrolase Epoxide hydrolase Gut esterase 1 MOSC domain-containing protein MOSC domain-containing protein MOSC domain-containing protein Probable cytochrome P450 CYP36A1 Probable cytochrome P450 cyp-35D1	A0A0M7RF98 A0A1C3NSL8 A0A486WWU7 A4UVK7 G5ECD0 G5EDJ7 G5EE22 H2KY69 H2KYS3 H2L0K7 H9G2Y9 O01302 O02627 O02628 O02641 O16220 O16362 O16482 O16670 O16671 O16673 O44555 O44649 O44650 O44651 O44652 O44655 O44656 O44657 O44658 O44704 O44706 O45364 O45394 O45659 O61204 O61935 O62377 O62378 P90771 P91321 P92016 Q04457 Q19839 Q20315 Q20976 Q21266 Q22008 Q23068 Q23268 Q27465 Q27470 Q27471 Q27482 Q27499 Q4LDP0 Q8MQ23 Q93315 Q965T7 Q9N4Q4 Q9N5I1 Q9TZ58 Q9XW75 U4PC34	C45B11.6 CELE_F22B8.7 CELE_F53E10.1 CELE_F56A11.5 CELE_F58B4.2 CELE_K01A2.5 CELE_W01A11.1 alh-4 alh-5 cest-1 cest-1.1 cest-1.2 cest-12 cest-13 cest-16 cest-17 cest-19 cest-2.1 cest-2.2 cest-2.3 cest-24 cest-26 cyp-23A1 cyp-23a1 cyp-33A1 cyp-33B1 cyp-33C1 cyp-33C11 cyp-33C12 cyp-33C2 cyp-33C3 cyp-33C4 cyp-33C5 cyp-33C6 cyp-33C7 cyp-33C8 cyp-33C9 cyp-33D1 cyp-33D3 cyp-33E1 cyp-33E2 cyp-33E3 cyp-33a1 cyp-33b1 cyp-33c1 cyp-33c11 cyp-33c12 cyp-33c2 cyp-33c3 cyp-33c4 cyp-33c5 cyp-33c6 cyp-33c7 cyp-33c8 cyp-33c9 cyp-33d1 cyp-33d3 cyp-33e1 cyp-33e2 cyp-33e3 cyp-34A1 cyp-34A10 cyp-34A2 cyp-34A5 cyp-34A6 cyp-34A7 cyp-34A8 cyp-34A9 cyp-34a1 cyp-34a10 cyp-34a2 cyp-34a4 cyp-34a5 cyp-34a6 cyp-34a7 cyp-34a8 cyp-34a9 cyp-35A1 cyp-35A2 cyp-35A3 cyp-35A4 cyp-35A5 cyp-35B1 cyp-35B2 cyp-35B3 cyp-35C1 cyp-35a1 cyp-35a2 cyp-35a3 cyp-35a4 cyp-35a5 cyp-35b1 cyp-35b2 cyp-35b3 cyp-35c1 cyp-35d1 cyp-36A1 cyp36a1 cytb-5.1 dach-1 daf-9 ges-1 trcs-1	Caenorhabditis elegans
Phosphate bond hydrolysis by NTPDase proteins	Nucleoside-diphosphatase mig-23 Nucleoside-diphosphatase uda-1 Nucleoside-triphosphatase ntp-1	Q18411 Q21815 Q9XU84	mig-23 ntp-1 uda-1	Caenorhabditis elegans
Phospholipase C-mediated cascade: FGFR1	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Protein let-756	G5EEF1 Q10656 Q11184 Q18758 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-756	Caenorhabditis elegans
Phospholipase C-mediated cascade; FGFR4	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Protein let-756	G5EEF1 Q10656 Q11184 Q18758 Q9TZA0	egl-15 egl-17 klo-1 klo-2 let-756	Caenorhabditis elegans
Physiological factors	Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylesterase type B domain-containing protein Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Gut esterase 1 NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family NEPrilysin metallopeptidase family Neprilysin-11 Neprilysin-1 Neprilysin-21 Neprilysin-2 Neprilysin Neprilysin Neprilysin Neprilysin Neprilysin Peptidase M13 C-terminal domain-containing protein Peptidase M13 C-terminal domain-containing protein Peptidase M13 N-terminal domain-containing protein Peptidase_M13 domain-containing protein Peptidase_M13 domain-containing protein Peptidase_M13_N domain-containing protein	A0A131MCS3 A0A1C3NSL8 A0A5S9MNU9 G5ED52 G5EDJ7 H2KYL1 H2KZE5 H2L0K7 H9G2Y9 O01302 O16607 O16636 O16652 O16789 O16790 O16795 O16796 O44857 O45311 O45569 P92016 Q04457 Q18673 Q21266 Q22008 Q22523 Q22763 Q23268 Q23427 Q400M1 Q4LDP0 Q8MQ23 Q9U2T0 Q9U2T1 Q9XW75	CELE_F41C6.4 cest-1 cest-1.1 cest-1.2 cest-12 cest-13 cest-16 cest-17 cest-19 cest-2.1 cest-2.2 cest-2.3 cest-24 cest-26 ges-1 nep-1 nep-10 nep-11 nep-12 nep-13 nep-16 nep-17 nep-18 nep-2 nep-20 nep-21 nep-22 nep-23 nep-24 nep-25 nep-26 nep-3 nep-4 nep-6 nep-8 nep-9	Caenorhabditis elegans
Platelet degranulation	Acetylcholine regulator unc-18 Actin-1 Actin-2 Actin-3 Actin-4 Alpha-actinin, sarcomeric Amyloid-beta-like protein Anaphase-promoting complex subunit 4-like WD40 domain-containing protein BMP-like protein unc-129 CYRIA/CYRIB Rac1 binding domain-containing protein Cadherin domain-containing protein Calponin-homology (CH) domain-containing protein Cathepsin F Cdc37 Hsp90 binding domain-containing protein Chitinase domain-containing protein 1 Cysteine proteinase Cysteine proteinase Dauer larva development regulatory growth factor daf-7 EF-hand domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein ELRR (Extracellular Leucine-Rich Repeat) ONly FERM domain-containing protein Fibronectin type-III domain-containing protein Fructose-bisphosphate aldolase 1 Fructose-bisphosphate aldolase 2 Hyaluronan/mRNA-binding protein domain-containing protein ILEI/PANDER domain-containing protein Ig-like and fibronectin type-III domain-containing protein 1 Ig-like and fibronectin type-III domain-containing protein 2 Ig-like and fibronectin type-III domain-containing protein C27B7.7 Ig-like domain-containing protein Ig-like domain-containing protein Integrin alpha pat-2 Integrin beta pat-3 Kringle domain-containing protein LAMP family protein lmp-1 Lipid droplet localized protein Lysosome-associated membrane glycoprotein 5 MICOS complex subunit MIC27 Mesencephalic astrocyte-derived neurotrophic factor homolog Multidrug resistance-associated protein lethal(2)03659 NTR domain-containing protein Obg-like ATPase 1 Papain family cysteine protease Pept_C1 domain-containing protein Pept_C1 domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Peptidase C1A papain C-terminal domain-containing protein Phosphatase and actin regulator 2 Platelet-derived growth factor (PDGF) family profile domain-containing protein Probable Hsp90 co-chaperone cdc37 Protein dbl-1 Protein lin-49 Protein unc-112 Putative metalloproteinase inhibitor tag-225 Rab27 SCAVenger receptor (CD36 family) related SCAVenger receptor (CD36 family) related SCAVenger receptor (CD36 family) related SERPIN domain-containing protein SERPIN domain-containing protein SPARC Saposin B-type domain-containing protein Saposin B-type domain-containing protein Sensory neuron membrane protein 2 Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Sulfhydryl oxidase Superoxide dismutase [Cu-Zn] Sushi domain-containing protein Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Syntaxin-binding protein 1 Tetraspanin Tetraspanin Thioredoxin domain-containing protein Torsin-like protein Torsin Torsin Tr-type G domain-containing protein Uncharacterized integrin beta-like protein C05D9.3 Uncharacterized protein C03F11.3 Uncharacterized protein R07B1.3 Vinculin	A0A1N7SYP5 A9Z1L1 G5EBM7 G5EBS5 G5EBY8 G5ECY2 G5EE40 G5EEL5 G5EFH4 G5EFK8 G5EGK1 H2KYR1 H2KZY5 H2L0F2 O01764 O02108 O16454 O17255 O17365 O17939 O18016 O18023 O44191 O44412 O45271 O45520 P0DM41 P0DM42 P10984 P10986 P19826 P34446 P34697 P34714 P34815 P46563 P54216 P91110 P91823 P91855 P91917 P92172 Q09387 Q09606 Q10651 Q11117 Q11124 Q17526 Q18096 Q18136 Q18245 Q18276 Q18279 Q18287 Q18607 Q18685 Q18740 Q18849 Q19140 Q19344 Q19625 Q19651 Q19663 Q20318 Q21154 Q21265 Q21267 Q21810 Q22174 Q23030 Q23158 Q27874 Q2AAB9 Q5F4U0 Q688B0 Q93539 Q95NU5 Q9BL26 Q9GYK0 Q9GYK2 Q9GZE9 Q9N3B0 Q9N413 Q9N4L6 Q9U2X1 Q9XTT3 Q9XVI4 Q9XVQ1 Q9XXG5 Q9XXQ7 U4PBJ9 U4PME4	C03F11.3 C05D9.3 C18E9.7 C27B7.7 C28G1.2 C32B5.13 C32B5.7 C54G4.4 CELE_F14B4.1 CELE_F15D3.4 CELE_F21C10.7 CELE_F26H9.2 CELE_F44G3.7 CELE_F47B7.2 CELE_K02E7.10 CELE_K07E8.6 CELE_R07E3.1 CELE_R07G3.8 CELE_R09F10.1 CELE_T22A3.6 CELE_Y113G7B.15 CELE_Y51A2D.8 CELE_Y71H2AM.25 CELE_Y71H2AR.2 CELE_ZK973.11 R07B1.3 act-1 act-2 act-3 act-4 aex-6 aipl-1 aldo-1 aldo-2 apl-1 atn-1 cal-5 cdc-37 cdh-10 cet-1 cfh-1 chil-10 daf-7 dbl-1 deb-1 famp-1 fln-1 igdb-1 igdb-2 iglr-1 lan-2 ldp-1 lin-49 lmp-1 lmp-2 lron-6 manf-1 moma-1 mrp-6 ola-1 ooc-5 ost-1 pat-2 pat-3 pvf-1 rab27 rme-2 scav-2 scav-3 scav-4 scav-6 slfl-5 sod-1 sparc spp-10 spp-8 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 tag-196 tag-210 tag-225 tag-329 timp-1 tln-1 tor-1 tor-2 tsp-11 tsp-7 unc-112 unc-129 unc-18 uncp-18 vig-1	Caenorhabditis elegans
Platelet homeostasis	1-alkyl-2-acetylglycerophosphocholine esterase Platelet-activating factor acetylhydrolase homolog 2	G5EGT1 Q22943	paf-1 paf-2	Caenorhabditis elegans

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