GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1651 - 1675** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Imatinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Sunitinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Signaling by kinase domain mutants of KIT	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Signaling by extracellular domain mutants of KIT	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Regorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Sorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Masitinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Signaling by juxtamembrane domain KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
KIT mutants bind TKIs	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Toxicity of botulinum toxin type B (botB)	Botulinum neurotoxin type B HA-17 HA-33 protein Ha70 protein NTNHA Synaptotagmin-1 Synaptotagmin-2 Vesicle-associated membrane protein 2	P10844 P21579 P63027 Q45877 Q45878 Q57230 Q8N9I0 Q9LBS8	HA HA-17 HA-33 SVP65 SYB2 SYT SYT1 SYT2 VAMP2 botB ha17 ha34 ha70 ntnha	Homo sapiens (human)
ATF6 (ATF6-alpha) activates chaperone genes	Calreticulin Cyclic AMP-dependent transcription factor ATF-4 Cyclic AMP-dependent transcription factor ATF-6 alpha DNA damage-inducible transcript 3 protein Endoplasmic reticulum chaperone BiP Endoplasmin Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma	P11021 P14625 P18848 P18850 P23511 P25208 P27797 P35638 Q13952	ATF4 ATF6 CALR CHOP CHOP10 CREB2 CRTC DDIT3 GADD153 GRP78 GRP94 HAP3 HSP90B1 HSPA5 HSPC4 NFYA NFYB NFYC TRA1 TXREB	Homo sapiens (human)
Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1)	Solute carrier family 2, facilitated glucose transporter member 1	P11166	GLUT1 SLC2A1	Homo sapiens (human)	G58161NS
Intestinal hexose absorption	Regulatory solute carrier protein family 1 member 1 Sodium/glucose cotransporter 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 5	P11168 P13866 P22732 Q92681	GLUT2 GLUT5 NAGT RSC1A1 SGLT1 SLC2A2 SLC2A5 SLC5A1	Homo sapiens (human)	G58161NS G93924TT
Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS)	Solute carrier family 2, facilitated glucose transporter member 2	P11168	GLUT2 SLC2A2	Homo sapiens (human)	G58161NS G93924TT
Pyrimidine biosynthesis	Dihydroorotate dehydrogenase (quinone), mitochondrial Multifunctional protein CAD Uridine 5'-monophosphate synthase	P11172 P27708 Q02127	CAD DHODH UMPS	Homo sapiens (human)
Acetylation	Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2	P11245 P18440	AAC1 AAC2 NAT1 NAT2	Homo sapiens (human)
STAT5 activation downstream of FLT3 ITD mutants	Bcl-2-like protein 1 Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 NADPH oxidase 4 Receptor-type tyrosine-protein kinase FLT3 Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P11309 P36888 P38936 P42229 P51692 P62993 Q06124 Q07817 Q9NPH5 Q9UQC2	ASH BCL2L BCL2L1 BCLX CAP20 CD135 CDKN1 CDKN1A CIP1 FLK2 FLT3 GAB2 GRB2 KIAA0571 MDA6 NOX4 PIC1 PIM1 PTP2C PTPN11 RENOX SDI1 SHPTP2 STAT5 STAT5A STAT5B STK1 WAF1	Homo sapiens (human)
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P28330 P40939 P42126 P55084 Q16698	ACADL ACADM DCI DECR DECR1 ECI1 HADH HADHA HADHB SDR18C1	Homo sapiens (human)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl-carrier-protein] reductase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P30084 P40939 P55084 Q16836 Q9BV79	ACADM ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC MECR NBRF1 SCHAD	Homo sapiens (human)
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P30084 P40939 P55084 Q16836	ACADM ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD	Homo sapiens (human)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Protein-tyrosine kinase 6	P11802 P24385 P24864 P24941 P46527 Q13882	BCL1 BRK CCND1 CCNE CCNE1 CDK2 CDK4 CDKN1B CDKN2 KIP1 PRAD1 PTK6 p27	Homo sapiens (human)
Drug-mediated inhibition of CDK4/CDK6 activity	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3	P11802 P24385 P30279 P30281 Q00534	BCL1 CCND1 CCND2 CCND3 CDK4 CDK6 CDKN6 PRAD1	Homo sapiens (human)
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A	P11802 P42771 Q00534	CDK4 CDK6 CDKN2 CDKN2A CDKN6 MTS1	Homo sapiens (human)
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4	Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 2A	P11802 P42771	CDK4 CDKN2 CDKN2A MTS1	Homo sapiens (human)

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