GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **1070** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Dectin-1 mediated noncanonical NF-kB signaling	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit Nuclear factor kappa B subunit 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta RELB proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-conjugating enzyme E2M Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZYZ8 A0A8I6A5Y3 A0A8I6ANR6 A0A8I6G2R1 A0A8I6G6F3 A0A8I6GIW9 B0BN93 D3ZTD1 D4A8H1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q99MI7 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Chuk Cul1 Fbxw11 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Map3k14 Mecl1 Mss1 Nfkb2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Relb Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba3 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube1c Ube2m	Rattus norvegicus (Norway rat)
Dectin-2 family	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 C-type lectin domain family 4 member D C-type lectin domain family 4 member E High affinity immunoglobulin epsilon receptor subunit gamma Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK	P20411 P24135 Q07014 Q62844 Q64725 Q67EQ1 Q69FH1	Clec4d Clec4e Clecsf8 Clecsf9 Fce1g Fcer1g Fyn Lyn Mcl Mincle Plcg2 Syk	Rattus norvegicus (Norway rat)
Defensins	Alpha-defensin N-terminal domain-containing protein Beta-defensin 14 Beta-defensin 17 Beta-defensin 18 Beta-defensin 1 Beta-defensin 25 Beta-defensin 30 Beta-defensin 41 Beta-defensin 43 Beta-defensin 4 Beta-defensin Beta-defensin Beta-defensin Beta-defensin Defensin alpha 10 Defensin alpha 11 Defensin alpha 24 Defensin alpha 4 Defensin alpha 6 Defensin alpha 8 Defensin alpha 9 Defensin alpha-like protein 1 Neutrophil antibiotic peptide NP-2 Neutrophil antibiotic peptide NP-3B	A0A8I6GLV0 A0A8J8YAJ6 F1LSU5 F7EMF7 F7FD31 O88514 O89117 Q32ZF3 Q32ZF5 Q32ZG2 Q32ZG7 Q32ZH1 Q32ZH4 Q32ZH5 Q32ZH7 Q4JEI2 Q4JEI3 Q4JEI5 Q4JEI6 Q4JEI8 Q4JEI9 Q62714 Q62715 Q9Z1F1	Defa Defa-rs1 Defa10 Defa11 Defa24 Defa6 Defa8 Defa9 Defal1 Defb1 Defb14 Defb17 Defb18 Defb2 Defb21 Defb24 Defb25 Defb28 Defb3 Defb30 Defb36 Defb4 Defb41 Defb43 Defcr4 ENSRNOG00000064390 Np4 Rd5	Rattus norvegicus (Norway rat)
Degradation of AXIN	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Axin-1 Axin-2 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase Poly [ADP-ribose] polymerase Poly [ADP-ribose] polymerase Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JTB0 A0A0G2KAX0 A0A8I5Y0P5 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 B0BN93 D3Z8Q6 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O70239 O70240 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIK5 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q9JHW0 Q9WTV5 Q9Z2X3	Axin Axin1 Axin2 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ring12 Rnf146 Rps27a Smurf2 Sug1 Tbp1 Tbp7 Tnks Tnks2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Degradation of DVL	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 Dishevelled-binding antagonist of beta-catenin 1 HECT-type E3 ubiquitin transferase Kelch-like protein 12 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 Segment polarity protein dishevelled homolog DVL-1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6AG92 A0A8I6GKX7 B0BN93 B5DF89 D3ZB71 D4A3W8 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q8R2H4 Q9JHW0 Q9WTV5 Q9WVB9 Q9Z2X3	C3ip1 Cul3 Dact1 Dvl1 Dvl2 Dvl3 Hecw1 Klhl12 LOC100360645 LOC100360846 LOC100361515 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Degradation of GLI1 by the proteasome	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 E3 ubiquitin-protein ligase GLI family zinc finger 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein numb homolog Ring-box 1 S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZZU1 A0A8I6A5Y3 A0A8I6A606 A0A8I6G2R1 B0BN93 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V6X8 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q2LC84 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Cul1 Gli1 Itch LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Numb Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sufu Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Degradation of beta-catenin by the destruction complex	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Beta-transducin repeat containing E3 ubiquitin protein ligase Casein kinase I isoform alpha Catenin beta-1 Cullin 1 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein phosphatase 2 scaffold subunit A alpha Ring-box 1 S-phase kinase-associated protein 1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZMG6 A0A8I5ZNE7 A0A8I5ZRC2 A0A8I6A5Y3 A0A8I6A6K6 A0A8I6G2R1 B0BN93 D3ZCP6 D3ZDI7 D4A3I0 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O70239 O88761 P0CG51 P17220 P18266 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62716 P62982 P63331 P70478 P97633 Q4FZT9 Q4KM35 Q4QQT4 Q4V8E2 Q5XI34 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q80W83 Q9JHW0 Q9WTV5 Q9WU82 Q9Z2X3	Amer1 Apc Axin Axin1 Btrc Catnb Csnk1a1 Ctnnb1 Cul1 Gsk3b LOC100360606 LOC100360645 LOC100360846 LOC100365869 LOC100909468 Lmp10 Lmp2 Mecl1 Mss1 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Zranb1	Rattus norvegicus (Norway rat)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Cystathionine gamma-lyase Cysteine dioxygenase type 1 Flavin-containing monooxygenase 1 Glutamate decarboxylase-like 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	A0A8I5ZWY4 A0A8I6AWC8 P18757 P21816 P24329 P36365 P97532 P97615	Ado Cdo1 Cth Fmo-1 Fmo1 Gadl1 Mpst Trx2 Tst Txn2	Rattus norvegicus (Norway rat)
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 (Fragment) ADAM metallopeptidase domain 8 ADAM metallopeptidase with thrombospondin type 1 motif, 5 Aggrecan core protein Alpha-2-macroglobulin Basigin Brevican core protein CD44 antigen Cadherin-1 Calpain 11 Calpain 12 Calpain 15 Calpain 7 Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-10 Calpain-13 Calpain-2 catalytic subunit Calpain-3 Calpain-5 Calpain-6 Calpain-8 Calpain-9 Calpastatin Cathepsin G Cathepsin K Cathepsin S Collagenase 3 (Fragment) Decorin Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 15 Elastase, neutrophil expressed Macrophage metalloelastase Matrilysin Matrix metallopeptidase 20 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Neutrophil collagenase Opticin Osteopontin Procathepsin L Serine protease HTRA1 Signal peptide, CUB domain and EGF like domain containing 1 Signal peptide, CUB domain and EGF like domain containing 3 Stromelysin-1 Stromelysin-2 Stromelysin-3 Transmembrane serine protease 6 interstitial collagenase	A0A096MK02 A0A0G2KAS0 A0A8I6A3P6 A0A8I6G6J0 B5DFD5 D3ZB52 D3ZJZ8 D3ZXD9 D4A488 F1M987 G3V673 O35186 O35920 O88501 O88766 P03957 P06238 P07152 P07154 P07897 P08721 P16259 P17977 P23097 P26051 P26453 P27321 P33436 P50280 P50282 P55068 P97571 Q01129 Q02765 Q07009 Q10739 Q10743 Q499S5 Q499T5 Q4V8Q1 Q5BK10 Q63341 Q64537 Q78EJ9 Q8R4C0 Q9ES66 Q9ESP7 Q9QYV0 Q9QZK5 Q9R0T4	2b7 A2m A2m1 Acan Adam10 Adam15 Adam8 Adamts4 Adamts5 Agc Agc1 Bcan Behab Bsg Capa6 Capn1 Capn10 Capn11 Capn12 Capn13 Capn15 Capn2 Capn3 Capn4 Capn5 Capn6 Capn7 Capn8 Capn9 Capns1 Cast Cd44 Cdh1 Cls1 Cls4 Css1 Ctsg Ctsk Ctsl Ctsl1 Ctss Dcn Elane Htra Htra1 Madm Mdc15 Mmel Mmp-7 Mmp1 Mmp10 Mmp11 Mmp12 Mmp13 Mmp14 Mmp1a Mmp2 Mmp20 Mmp3 Mmp7 Mmp8 Mmp9 Mtmmp Ncl2 Ncl4 Optc Prss11 Scube1 Scube3 Spp-1 Spp1 Tmprss6	Rattus norvegicus (Norway rat)
Depolymerization of the Nuclear Lamina	CTD nuclear envelope phosphatase 1 Cyclin-dependent kinase 1 Emerin G2/mitotic-specific cyclin-B1 Lamin-B1 Nuclear envelope phosphatase-regulatory subunit 1 Prelamin-A/C Protein kinase C alpha type Protein kinase C beta type RNA binding motif protein 39 phosphatidate phosphatase phosphatidate phosphatase phosphatidate phosphatase	A0A0G2JW03 A0A0G2JY62 A0A8I6AUU1 A0A8J8XIU8 D3ZJA8 P05696 P30277 P39951 P48679 P68403 P70615 Q3B7T6 Q63190	Ccnb1 Cdc2 Cdc2a Cdk1 Cdkn1 Cnep1r1 Ctdnep1 Dullard Emd Lmn1 Lmna Lmnb1 Lpin1 Lpin2 Lpin3 Pkca Pkcb Prkca Prkcb Prkcb1 Rbm39 Tmem188	Rattus norvegicus (Norway rat)
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein T Centromere protein U Centromere protein W Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 MIS18 binding protein 1 Nucleophosmin Opa interacting protein 5 Protein Mis18-alpha RB binding protein 4, chromatin remodeling factor Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	A0A0G2JXI9 A0A0G2K615 A0A1W2Q6F6 A0A8I5ZQQ5 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A3Y0 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AQI0 A0A8I6AWT3 A0A8I6G659 A1L1L1 A9UMV8 B2RZC4 D3Z896 D3ZGQ8 D3ZKM9 D3ZVK7 D3ZXP3 D4A1W1 D4A9X9 D4AC25 D4ACM0 E9PSW8 F1M389 G3V9C7 M0RBQ5 P0CC09 P13084 P60123 P62804 Q00729 Q3ZAU7 Q4V8G7 Q561R1 Q5U1Z7 Q5U2W4 Q63517 Q66H02 Q71UF4	Cenpc Cenpc1 Cenph Cenpi Cenpk Cenpl Cenpm Cenpn Cenpo Cenpp Cenpq Cenpr Cenpt Cenpu Cenpw Cug2 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Fshprh1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist4 Hist4h4 Hjurp Itgb3bp Knl1 LOC100365043 LOC100910200 LOC120097726 LOC679342 LOC681185 LOC684797 Lrpr1 Mis18a Mis18bp1 Mlf1ip Npm1 Nrif3 Oip5 Rbbp4 Rbbp7 Rsf1 Ruvbl1 Smarca5 Th2b Tip49 Tip49a	Rattus norvegicus (Norway rat)
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Dermatan sulfate epimerase-like Dermatan sulfate epimerase Neurocan core protein Uronyl-2-sulfotransferase Versican core protein (Fragments)	A0A0G2JU02 D3ZPB6 D3ZYE3 M0R8Y4 P47853 P55067 P55068 Q00657 Q01129 Q9ERB4 Q9ERQ6	Bcan Behab Bgn Caleb Chst14 Cspg2 Cspg3 Cspg4 Cspg5 Dcn Dse Dsel Ncan Ng2 Ngc Ust Vcan	Rattus norvegicus (Norway rat)
Detoxification of Reactive Oxygen Species	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Copper chaperone for superoxide dismutase Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c domain-containing protein Cytochrome c, somatic ERO1-like protein alpha Epididymal secretory glutathione peroxidase Extracellular superoxide dismutase [Cu-Zn] Glutathione S-transferase P Glutathione peroxidase 1 Glutathione peroxidase 2 Glutathione peroxidase 3 Glutathione peroxidase 6 Glutathione peroxidase Glutathione peroxidase Glutathione reductase (Fragment) NADPH oxidase 4 Neutrophil cytosol factor 2 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Peroxiredoxin-6 Protein disulfide-isomerase Similar to Cytochrome c, somatic Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	A0A8I5ZNF3 A0A8I6ARN0 A7E3N2 D3ZPW7 D3ZXV2 D4A5L9 F1M707 O35244 O89049 P04041 P04762 P04785 P04906 P07632 P07895 P11232 P23764 P30710 P35704 P62898 P70619 P83645 P97615 Q08420 Q62737 Q63716 Q64625 Q6PEC0 Q8R4A1 Q924V1 Q9ERL1 Q9JK72 Q9R063 Q9Z0J5 Q9Z0V6	AC128290.1 Aipla2 Aop2 Cas1 Cat Ccs Cyba Cybb Cycs Cycsl2 Cycsl3 Ero1a Ero1l Giig11 Gpx1 Gpx2 Gpx3 Gpx5 Gpx6 Gpx7 Gpx8 Gsr Gstp1 Kox LOC690675 Ncf1 Ncf2 Ncf4 Nox4 Nudt2 P4hb Pdia1 Prdx1 Prdx2 Prdx3 Prdx5 Prdx6 RGD1562558 Sod-3 Sod1 Sod2 Sod3 Tdpx1 Tdpx2 Trx2 Trxr1 Trxr2 Tsa Txn Txn1 Txn2 Txnrd1 Txnrd2	Rattus norvegicus (Norway rat)
Digestion	Guanylate cyclase activator 2B Guanylin Guanylyl cyclase C Intestinal-type alkaline phosphatase 1 Pirin	P15693 P23897 P28902 P70668 Q5M827	Alpi Guc2c Guca2 Guca2a Guca2b Gucy2c Pir	Rattus norvegicus (Norway rat)
Digestion of dietary carbohydrate	Acidic mammalian chitinase Alpha-amylase Lactase/phlorizin hydrolase Sucrase-isomaltase, intestinal chitinase	A0A8I5YBI0 A0S5V8 P23739 Q02401 Q6RY07	Chia Chit1 LOC120100609 Lct Lph Si	Rattus norvegicus (Norway rat)	G58161NS G74621DY G80384UV G93924TT G96370VA
Digestion of dietary lipid	Bile salt-activated lipase Colipase Gastric triacylglycerol lipase Inactive pancreatic lipase-related protein 1 Pancreatic lipase-related protein 2 Pancreatic triacylglycerol lipase	P04634 P07882 P17084 P27657 P54316 P54318	Cel Clps Lipf Plrp1 Plrp2 Pnlip Pnliprp1 Pnliprp2	Rattus norvegicus (Norway rat)
Dimerization of procaspase-8	CASP8 and FADD-like apoptosis regulator Caspase-8 FAS-associated death domain protein Receptor interacting serine/threonine kinase 1 TNF receptor superfamily member 10b TNF receptor-associated factor Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	A0A0G2JZE1 A0A0U5J7B5 B5DFH7 C0H5Y5 D3ZYL0 D3ZZC5 P36940 Q63199 Q8R2E7 Q9JHX4	AABR07018323.1 Apt1 Apt1Lg1 Casp8 Cd95l Cflar Fadd Fas Fasl Faslg Ripk1 Tnfrsf10b Tnfrsf6 Tnfsf10 Tnfsf6 Tnlg6a Tradd Traf2	Rattus norvegicus (Norway rat)
Disassembly of the destruction complex and recruitment of AXIN to the membrane	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Catenin beta-1 Caveolin-1 Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 FRAT regulator of WNT signaling pathway 1 FRAT regulator of WNT signaling pathway 2 Frizzled-1 Frizzled-2 Frizzled-5 Glycogen synthase kinase-3 beta Low-density lipoprotein receptor-related protein Low-density lipoprotein receptor-related protein Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein phosphatase 2 scaffold subunit A alpha Segment polarity protein dishevelled homolog DVL-1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	A0A0G2K0H3 A0A8I5ZMG6 A0A8I5ZRC2 A0A8I6A4C8 A0A8I6A6K6 A0A8I6G721 A0A8I6GKX7 D3ZB71 D3ZCP6 D3ZDI7 D3ZND6 D4A9D7 D4A9J2 F1M077 M0R5Z2 O70239 P18266 P41350 P62716 P63331 P70478 P97633 Q08463 Q08464 Q4QQT4 Q5XI34 Q80W83 Q8CHL0 Q9WU82 Q9WVB9	Amer1 Apc Axin Axin1 Catnb Cav Cav1 Csnk1a1 Ctnnb1 Dvl1 Dvl2 Dvl3 Frat1 Frat2 Fzd1 Fzd2 Fzd5 Gsk3b LOC100361515 LOC100909468 LOC679110 Lrp5 Lrp6 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Wnt1 Wnt3a Wnt8a Wnt8b	Rattus norvegicus (Norway rat)
Disinhibition of SNARE formation	Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Syntaxin binding protein 3 Syntaxin-4	P05696 P63319 P68403 Q08850 Q99PV2	Pkca Pkcb Pkcc Pkcg Prkca Prkcb Prkcb1 Prkcc Prkcg Stx4 Stx4a Stxbp3 munc-18c	Rattus norvegicus (Norway rat)
Dissolution of Fibrin Clot	Annexin A2 Glia-derived nexin Histidine-rich glycoprotein Plasminogen activator inhibitor 1 Plasminogen activator inhibitor 2 type A Plasminogen Protein S100-A10 Serpin B6 Serpin family B member 8 Serpin family F member 2 Tissue-type plasminogen activator Urokinase plasminogen activator surface receptor Urokinase-type plasminogen activator	A0A8I6A6H8 A0A8I6AQI7 D3ZHB5 P05943 P07092 P19637 P20961 P29524 P29598 P49616 Q01177 Q07936 Q99PS8	Anx2 Anxa2 Hrg Hrg1 Pai1 Pai2 Pi7 Planh1 Planh2 Plat Plau Plaur Plg Pn1 S100a10 Serpinb2 Serpinb6a Serpinb8 Serpine1 Serpine2 Serpinf2	Rattus norvegicus (Norway rat)
Dopamine Neurotransmitter Release Cycle	Amyloid-beta A4 precursor protein-binding family A member 1 Complexin-1 Liprin-alpha-3 Liprin-alpha-4 (Fragment) PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral plasma membrane protein CASK Peripheral-type benzodiazepine receptor-associated protein 1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2	A0A1B0GWS0 A0A8I6AK94 O35430 O70441 P09951 P21707 P32851 P60881 P61765 P63012 P63041 P63045 Q01827 Q62769 Q62915 Q63537 Q792I0 Q91Z79 Q91Z80 Q9JIR0 Q9JIR4 Q9Z250 Q9Z252	Apba1 Bzrap1 Cask Cplx1 Lin7a Lin7b Lin7c Mals1 Mals2 Mals3 Mint1 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Rab3a Rbp1 Rim1 Rims1 Sap Slc18a2 Snap Snap25 Stx1a Stxbp1 Svat Syb2 Syn1 Syn2 Syn3 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Veli1 Veli1a Veli2 Veli3 Vmat2 X11	Rattus norvegicus (Norway rat)
Dopamine receptors	D(1B) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor D(4) dopamine receptor	P19020 P25115 P30729 P61169	Drd2 Drd3 Drd4 Drd5	Rattus norvegicus (Norway rat)
Downregulation of ERBB2 signaling	Betacellulin Cullin-5 Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Megakaryocyte-associated tyrosine-protein kinase Neuregulin 3 Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein phosphatase non-receptor type 12 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A8I5Y1H8 A0A8I6A5Y3 A0A8I6AHV1 A0A8I6AQ55 G3V6K6 G3V7Q4 O35569 P06494 P07522 P0CG51 P41243 P43322 P62982 P82995 Q06175 Q62799 Q63429 Q63692 Q9JJ31 Q9Z0L5	Batk Btc Cdc37 Ctk Cul5 Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Hsp86 Hsp90aa1 Hspca LOC100360645 Matk Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Ptpn12 Ptpn18 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vacm1	Rattus norvegicus (Norway rat)
Downregulation of ERBB2:ERBB3 signaling	E3 ubiquitin-protein ligase NRDP1 Polyubiquitin-B Polyubiquitin-C Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A8I6A5Y3 D3ZN39 G3V930 O35569 P06494 P0CG51 P43322 P47196 P47197 P62982 Q62799 Q63429 Q63484	Akt1 Akt2 Akt3 Erbb2 Erbb3 LOC100360645 Ndf Neu Nrg1 Nrg2 Ntak Rnf41 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Usp8	Rattus norvegicus (Norway rat)
Downregulation of SMAD2/3:SMAD4 transcriptional activity	E3 ubiquitin-protein ligase HECT-type E3 ubiquitin transferase Histone deacetylase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Nuclear receptor co-repressor 2 Poly [ADP-ribose] polymerase 1 Polyubiquitin-B Polyubiquitin-C Protein ATP1B4 Protein phosphatase 1A SKI-like proto-oncogene SNW domain-containing protein 1 Ski oncogene TGFB-induced factor homeobox 1 Tripartite motif-containing 33 Ubiquitin B-like Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JU91 A0A0G2K628 A0A8I5Y0P5 A0A8I5ZP60 A0A8I5ZTL5 A0A8I6A5Y3 A0A8I6AEH7 D3ZDK2 D3ZUK4 D3ZWL1 O70436 O70437 P0CG51 P20650 P21708 P27008 P61078 P62982 P63086 P84025 Q4QQW4 Q63429 Q9R193	Adprt Atp1b4 Erk1 Erk2 Hdac1 LOC100360645 Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Ncor2 Nedd4l Parp1 Pp2c1 Ppm1a Pppm1a Prkm1 Prkm3 Rps27a Ski Skil Smad2 Smad3 Smad4 Smurf2 Snw1 Tgif1 Trim33 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2d1 Ube2d3	Rattus norvegicus (Norway rat)

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