GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **1070** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor	A0A0G2K210 A0A8I6B5D5 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P48807 P61149 P63076 Q8VI82 Q9EST9	Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Plcg1	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho beta	A0A8I6B5D5 D3Z8T6 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P61149 P63076 Q498D6 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Klb Plcg1	Rattus norvegicus (Norway rat)
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Integrin beta-3 Integrin subunit alpha V Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Platelet endothelial cell adhesion molecule Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	F1LM93 F1LZX9 P10686 P41499 P81718 P97573 Q01621 Q07014 Q3SWT0 Q62844 Q8R2H2 Q9WUD9	Fyn Inpp5d Itgav Itgb3 Lck Lyn Pecam Pecam1 Plcg1 Ptph6 Ptpn11 Ptpn6 Ship Ship1 Src Yes1	Rattus norvegicus (Norway rat)
Activated NTRK3 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 NT-3 growth factor receptor Neurotrophin-3	P10686 P18280 Q03351	Ntf-3 Ntf3 Ntrk3 Plcg1 Trkc	Rattus norvegicus (Norway rat)
GPVI-mediated activation cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3-phosphoinositide-dependent protein kinase 1 C-type lectin domain family 1 member B Cell division control protein 42 homolog Glycoprotein VI High affinity immunoglobulin epsilon receptor subunit gamma Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase, regulatory subunit 6 Podoplanin Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene vav Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5ZPB5 A0A8I6A1P8 A0A8I6G942 A0A8J8YIH6 D3ZFJ0 D3ZJD8 D3ZYG0 D4A4I3 M0R8A3 O55173 O70601 P20411 P24135 P41499 P54100 P61589 P62747 P81718 Q01621 Q07014 Q32PX6 Q62844 Q63787 Q63788 Q63789 Q64294 Q64725 Q6MG59 Q6RUV5 Q8CFN2 Q9Z1L0	Arha Arha2 Arhb Cdc42 Clec1b Fce1g Fcer1g Fyn G6b Gp6 Lat Lck Lcp2 Lyn Mpig6b Pdk1 Pdpk1 Pdpn Pik3ca Pik3cb Pik3cg Pik3r1 Pik3r2 Pik3r3 Pik3r5 Pik3r6 Plcg2 Ptph6 Ptpn11 Ptpn6 Rac Rac1 Rac2 Rhoa Rhob Rhog Syk Vav Vav1 Vav2 Vav3	Rattus norvegicus (Norway rat)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 B-cell linker protein B-cell receptor CD22 CD19 molecule CD79a molecule CD79b molecule Cytoplasmic protein Dual adaptor of phosphotyrosine and 3-phosphoinositides 1 Growth factor receptor-bound protein 2 Ig kappa chain V-II region RPMI 6410-like Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin heavy variable V12-3 Immunoglobulin kappa variable like, pseudogene 6 Immunoglobulin lambda constant 1 Immunoglobulin lambda-like polypeptide 1 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 MCG142154-like Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Proto-oncogene vav SH3 domain-containing kinase-binding protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Short transient receptor potential channel 1 Similar to immunoglobulin light chain variable region Similar to immunoglobulin light chain Stromal interaction molecule 1 Tyrosine-protein kinase SYK Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 6 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2JW41 A0A0G2JY98 A0A0G2JZL1 A0A0G2K066 A0A0G2K180 A0A0G2K3L5 A0A0G2K6M9 A0A0G2K828 A0A0G2K8K8 A0A0G2K980 A0A0G2K9L1 A0A0G2K9Z5 A0A8I5Y130 A0A8I5Y662 A0A8I5Y735 A0A8I5Y7P7 A0A8I5Y806 A0A8I5Y949 A0A8I5Y9R1 A0A8I5Y9S1 A0A8I5YBU3 A0A8I5YC48 A0A8I5ZLU0 A0A8I5ZMM5 A0A8I5ZN60 A0A8I5ZNF0 A0A8I5ZNL8 A0A8I5ZNW4 A0A8I5ZPH3 A0A8I5ZRU2 A0A8I5ZTK7 A0A8I5ZVJ7 A0A8I5ZX10 A0A8I5ZX42 A0A8I5ZY02 A0A8I5ZYE2 A0A8I5ZYV4 A0A8I6A2E5 A0A8I6A3F2 A0A8I6A6C3 A0A8I6A7L1 A0A8I6A935 A0A8I6A938 A0A8I6A9W1 A0A8I6AA60 A0A8I6AAM9 A0A8I6ABH0 A0A8I6AC42 A0A8I6ACJ3 A0A8I6ACY1 A0A8I6AD89 A0A8I6AEB7 A0A8I6AEV5 A0A8I6AFL1 A0A8I6AFR0 A0A8I6AGR0 A0A8I6AH36 A0A8I6AHB9 A0A8I6AHQ4 A0A8I6AHX0 A0A8I6AI41 A0A8I6AJ98 A0A8I6AJF8 A0A8I6AK51 A0A8I6AKK2 A0A8I6ALZ6 A0A8I6AM09 A0A8I6AMX1 A0A8I6ANN1 A0A8I6AP25 A0A8I6AQD7 A0A8I6ASD7 A0A8I6AVW1 A0A8I6G3M2 A0A8I6G7J3 A0A8I6G8Z3 A0A8I6GC23 A0A8I6GE36 A0A8I6GHG7 A0A8I6GL55 A0A8I6GLJ8 A0A8J8XPU7 B2RZ33 D3ZD88 D3ZE08 D3ZMS7 D3ZMY4 D3ZPL2 D4A3T0 D4ACC1 F1LNH2 F1LWD0 F1LYF1 F1LYU3 F1M784 F1M7B3 F1MAC3 F1MAM7 M0R5K1 M0R7F5 M0RBD5 M0RDZ5 P24135 P29994 P29995 P54100 P62994 P81718 P84903 Q4KM52 Q63269 Q63787 Q64725 Q925Q9 Q9QX01	AABR07034730.2 AABR07060971.1 AABR07061001.1 AABR07065782.1 AABR07065808.1 AABR07065812.2 AABR07065813.1 Ash Blnk Btk Cd19 Cd22 Cd79a Cd79b Dapp1 ENSRNOG00000062324 ENSRNOG00000062682 ENSRNOG00000062762 ENSRNOG00000062853 ENSRNOG00000062915 ENSRNOG00000062976 ENSRNOG00000063148 ENSRNOG00000063329 ENSRNOG00000063340 ENSRNOG00000063341 ENSRNOG00000063422 ENSRNOG00000063550 ENSRNOG00000063572 ENSRNOG00000063707 ENSRNOG00000063791 ENSRNOG00000064041 ENSRNOG00000064061 ENSRNOG00000064085 ENSRNOG00000064245 ENSRNOG00000064481 ENSRNOG00000064582 ENSRNOG00000065160 ENSRNOG00000065181 ENSRNOG00000065191 ENSRNOG00000065237 ENSRNOG00000065406 ENSRNOG00000065564 ENSRNOG00000065629 ENSRNOG00000065670 ENSRNOG00000065675 ENSRNOG00000065690 ENSRNOG00000065855 ENSRNOG00000066010 ENSRNOG00000066072 ENSRNOG00000066203 ENSRNOG00000066380 ENSRNOG00000066406 ENSRNOG00000066431 ENSRNOG00000066785 ENSRNOG00000066812 ENSRNOG00000066814 ENSRNOG00000066904 ENSRNOG00000066922 ENSRNOG00000066926 ENSRNOG00000066971 ENSRNOG00000067010 ENSRNOG00000067025 ENSRNOG00000067233 ENSRNOG00000067273 ENSRNOG00000067516 ENSRNOG00000067603 ENSRNOG00000067643 ENSRNOG00000067679 ENSRNOG00000067883 ENSRNOG00000068055 ENSRNOG00000068059 ENSRNOG00000068381 ENSRNOG00000068499 ENSRNOG00000068847 ENSRNOG00000069193 ENSRNOG00000069427 ENSRNOG00000069491 ENSRNOG00000069766 ENSRNOG00000069828 ENSRNOG00000069901 ENSRNOG00000069940 ENSRNOG00000070091 ENSRNOG00000070192 ENSRNOG00000070244 ENSRNOG00000070247 ENSRNOG00000070810 ENSRNOG00000070812 ENSRNOG00000070816 ENSRNOG00000070832 ENSRNOG00000070933 ENSRNOG00000071049 ENSRNOG00000071091 Grb2 Igkv2-112l1 Igkv8-30l1 Igkvl-ps6 Igkvl10 Igkvl12 Igkvl13 Igkvl2 Iglc1 Igll1 Insp3r Itpr1 Itpr2 Itpr3 LOC100361758 LOC100363522 LOC100365500 LOC100911032 LOC102551948 LOC690813 Nck1 Pik3ap1 Pik3cd Pik3r1 Plcg2 Ptph6 Ptpn6 RGD1561722 RGD1564696 Ruk Seta Sh3kbp1 Sim Sos1 Stim1 Syk Trp1 Trpc1 Vav Vav1	Rattus norvegicus (Norway rat)
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 B-cell lymphoma/leukemia 10 C-type lectin domain containing 7A Caspase recruitment domain-containing protein 9 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta MALT1 paracaspase Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B essential modulator Protein kinase C delta type Proto-oncogene tyrosine-protein kinase Src TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6	A0A0G2JW33 A0A0U1RRU5 A0A8I6ABN5 A0A8I6AH74 A0A8I6ANR6 B5DF45 D4A980 P09215 P0C8E4 P24135 Q5U303 Q6TMG5 Q9EPY0 Q9QY78 Q9QYN5 Q9WUD9	Bcl10 Card9 Chuk Clec7a Ikbkb Ikbkg Ikkb Malt1 Map3k7 Map3k7ip2 Nemo Pkcd Plcg2 Prkcd Src Tab1 Tab2 Tab3 Traf6	Rattus norvegicus (Norway rat)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Dynamin-2 Dynamin-3 Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain containing adaptor molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type	D3ZAS0 D3ZIP2 D3ZXR7 G3V6B9 P21575 P24135 P39052 Q08877 Q56DL5 Q63313 Q63691 Q6AXU0 Q9QX05	Bpi Cd14 Cd180 Dnm Dnm1 Dnm2 Dnm3 Dyn2 Dyn3 Lbp Ly86 Ly96 Plcg2 Ptpn4 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Dectin-2 family	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 C-type lectin domain family 4 member D C-type lectin domain family 4 member E High affinity immunoglobulin epsilon receptor subunit gamma Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK	P20411 P24135 Q07014 Q62844 Q64725 Q67EQ1 Q69FH1	Clec4d Clec4e Clecsf8 Clecsf9 Fce1g Fcer1g Fyn Lyn Mcl Mincle Plcg2 Syk	Rattus norvegicus (Norway rat)
Synthesis of PIPs at the Golgi membrane	1-phosphatidylinositol-3-phosphate 5-kinase ADP-ribosylation factor 1 ADP-ribosylation factor 3 Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase beta Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol polyphosphate 5-phosphatase type IV Phosphatidylinositol-3-phosphatase SAC1 Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphoinositide 3-kinase regulatory subunit 4 Protein VAC14 homolog Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2	A0A8I5YBG1 D3ZGS3 D3ZTF6 D4ADC8 O08561 O08662 O70173 O88763 P0C0R5 P61206 P84079 Q5XIL2 Q80W92 Q99M64 Q9ES21 Q9WVR1	Arf1 Arf3 Inpp5e Ocrl Pi4k2a Pi4k2b Pi4ka Pi4kb Pi4kii Pik3c2a Pik3c2g Pik3c3 Pik3r4 Pik4ca Pik4cb Pikfyve Sac1 Sacm1l Tpte Tpte2 Vac14 Vps34	Rattus norvegicus (Norway rat)
Synthesis of PIPs at the early endosome membrane	1-phosphatidylinositol-3-phosphate 5-kinase Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase F Myotubularin-related protein 12 Myotubularin-related protein 2 Myotubularin Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphoinositide 3-kinase regulatory subunit 4 Protein VAC14 homolog Type II inositol 3,4-bisphosphate 4-phosphatase protein-tyrosine-phosphatase	A0A8I5YBG1 A0A8I5ZTB8 A0A8I6AFY1 D3ZKG7 D3ZTF6 O88763 P0C0R5 Q5FVM6 Q5XIL2 Q62784 Q6AXQ4 Q80W92 Q99M64 Q9QWG5	Inpp4a Inpp4b Inpp5f Mtm1 Mtmr12 Mtmr2 Mtmr4 Pi4k2a Pi4k2b Pi4kii Pik3c2a Pik3c3 Pik3r4 Pikfyve Pip3ap Vac14 Vps34	Rattus norvegicus (Norway rat)
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial ADP-ribosylation factor GTPase-activating protein 3 Ankyrin repeat and LEM domain-containing protein 2 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cyto-kinesis 3 Dedicator of cytokinesis 2 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Delta(14)-sterol reductase LBR Desmoglein 2 Emerin Engulfment and cell motility 2 Extended synaptotagmin-1 Granule associated Rac and RHOG effector 1 Guanine nucleotide exchange factor DBS IQ motif containing GTPase activating protein 2 Integrin beta-1 Intersectin-1 Kalirin Kinectin 1 LOC687105 protein MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Membrane-associated progesterone receptor component 2 Mitochondrial proton/calcium exchanger protein Mitogen-activated protein kinase kinase kinase 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Phospholipase D1 Pleckstrin homology and RhoGEF domain containing G3 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene vav RNA binding motif protein 39 Ragulator complex protein LAMTOR1 Ras homolog family member G Ras-related protein Rab-7a Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Serine hydroxymethyltransferase Serine/threonine-protein kinase PAK 2 Starch-binding domain-containing protein 1 Synaptobrevin homolog YKT6 Syntaxin-5 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase	A0A0G2JVP1 A0A0G2JYR5 A0A0G2K7N9 A0A8I5ZK89 A0A8I5ZNR8 A0A8I5ZPB5 A0A8I5ZRJ5 A0A8I5ZRT6 A0A8I5ZXI2 A0A8I6A4W2 A0A8I6A9Q4 A0A8I6AEP6 A0A8I6AG90 A0A8I6AM38 A0A8I6GDA1 A0A8I6GLR6 A0A8J8XFB5 A0A8J8XIU8 A1A5P0 B2GUW2 B5DF62 D3ZA21 D3ZBN3 D3ZG43 D3ZKC8 D3ZYG0 D4A1D2 D4A8H8 D4AA32 E9PT59 F1LVW7 F1M0Z1 F1M4N6 F1MAK3 G3V982 P09527 P0CAX5 P26772 P41350 P49134 P54100 P63025 P70496 P81128 P97924 Q08851 Q32PX6 Q4KLN7 Q5EGY4 Q5FVN1 Q5U2Y3 Q5U3Z7 Q5XI73 Q5XIN6 Q5XIU9 Q62902 Q63190 Q63362 Q63406 Q63787 Q64303 Q66HA1 Q6P791 Q7TP65 Q8CFN2 Q99376 Q9EPF2 Q9WVE9 Q9Z1X1 Q9Z269	AABR07021955.1 Ankle2 Arfgap3 Arhgap1 Arhgap21 Arhgap32 Arhgap35 Arhgap5 Arhgdia Arhgdib Arhgdig Arhgef16 Arhgef26 Arhgef5 Borg5 Cav Cav1 Cdc42 Cdc42ep1 Cyfip1 Depdc1b Diaph3 Dock2 Dock3 Dock4 Dock5 Dsg2 Duo Ehsh1 Elmo2 Emd Epha2 Ergic53 Esyt1 Fam62a Garre1 Grlf1 Hapip Hspe1 Iqgap2 Itgb1 Itsn Itsn1 Kalrn Ktn1 LOC687105 Lamtor1 Lbr Lem4 Letm1 Lman1 Map3k11 Mbc2 Mcam Mcf2 Mcf2l Mlk3 Mpp7 Muc18 Ndufa5 Ndufs3 Ophn1 Ost P190A Pak2 Pak4 Pgrmc2 Pik3r1 Pld1 Plekhg3 Prex1 Rab7 Rab7a Rbm39 Rhog Shmt2 Stbd1 Stx5 Stx5a Syb3 Tfrc Trfr Trio Vamp3 Vangl1 Vapb Vav Vav1 Vav2 Vav3 Vrk2 Ykt6 p190ARHOGAP	Rattus norvegicus (Norway rat)
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase 5-formyltetrahydrofolate cyclo-ligase Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial C-1-tetrahydrofolate synthase, cytoplasmic Cytosolic 10-formyltetrahydrofolate dehydrogenase Dihydrofolate reductase Folate receptor beta Folylpolyglutamate synthase Methylenetetrahydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase Serine hydroxymethyltransferase Solute carrier family 25 member 32 formate--tetrahydrofolate ligase methenyltetrahydrofolate cyclohydrolase	A0A8I5Y115 A0A8I5ZRH3 A0A8I6A4C5 A0A8I6AG23 A0A8I6GID3 B2GUZ3 D3ZUA0 D4A4S5 M0R401 P27653 P28037 Q5EBA8 Q5U3Z7 Q62866 Q6TXG7 Q920D2	Aldh1l1 Aldh1l2 Dhfr Folr2 Fpgs Fthfd Hcp1 Mthfd Mthfd1 Mthfd1l Mthfd2 Mthfd2l Mthfr Mthfs Pcft Shmt1 Shmt2 Slc19a1 Slc25a32 Slc46a1	Rattus norvegicus (Norway rat)
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4 Corticosteroid-binding globulin Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Cytochrome P450 11B3, mitochondrial Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5, pseudogene 1 NADPH-dependent 3-keto-steroid reductase Hsd3b5 Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase	A0A140TAJ4 P01194 P11715 P15393 P16232 P22071 P22072 P27364 P30099 P30100 P31211 P50233 Q62878 Q64562	Cbg Cyp11b-1 Cyp11b-2 Cyp11b-3 Cyp11b1 Cyp11b2 Cyp11b3 Cyp17 Cyp17a1 Cyp21 Cyp21a1 Hsd11 Hsd11b1 Hsd11b2 Hsd11k Hsd3b Hsd3b1 Hsd3b5 Hsd3b5-ps1 Hsd3b6 Pomc Pomc2 Serpina6	Rattus norvegicus (Norway rat)
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase type 2 ATP-dependent translocase ABCB1 Albumin Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 Corticosteroid-binding globulin Cytochrome P450 3A18 Cytochrome P450 3A1 Cytochrome P450 3A2 Cytochrome P450 3A9 Cytochrome P450 3A UDP-glucuronosyltransferase 1-2 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B1 UDP-glucuronosyltransferase 2B2 UDP-glucuronosyltransferase 2B37 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase	A0A0G2K5K4 F1LTB8 P02770 P04800 P05183 P08541 P08542 P09875 P16232 P19488 P20720 P31211 P36511 P43245 P50233 P51538 Q3MHS3 Q62789 Q64581 Q64637 Q64638 Q6AYQ2	Abcb1 Akr1c1 Akr1c21 Alb Cbg Cyp3a-1 Cyp3a-2 Cyp3a1 Cyp3a11 Cyp3a13 Cyp3a18 Cyp3a2 Cyp3a62 Cyp3a9 Hsd11 Hsd11b1 Hsd11b2 Hsd11k Hsd17b5 Mdr1 Mdr1b Pgy1 RGD1559459 Serpina6 Udpgtr2 Ugt1 Ugt1a2 Ugt1a3 Ugt1a5 Ugt2b Ugt2b1 Ugt2b12 Ugt2b15 Ugt2b17 Ugt2b2 Ugt2b3 Ugt2b34l1 Ugt2b36 Ugt2b37 Ugt2b4 Ugt2b5 Ugt2b6 Ugt2b7 Ugt2b8	Rattus norvegicus (Norway rat)
pre-mRNA splicing	116 kDa U5 small nuclear ribonucleoprotein component Aly/REF export factor Apoptotic chromatin condensation inducer 1 Arsenite-resistance protein 2 BUD13 homolog Beta-catenin-like protein 1 CWC25 spliceosome-associated protein homolog Calcium homeostasis endoplasmic reticulum protein Cdc40 protein Cell division cycle 5-like protein Coiled-coil domain containing 12 Crooked neck-like protein 1 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Eukaryotic initiation factor 4A-III Family with sequence similarity 50, member A Fus RNA binding protein G patch domain containing 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 HIV-1 Tat specific factor 1 Heat shock cognate 71 kDa protein Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein A3-like Heterogeneous nuclear ribonucleoprotein C Heterogeneous nuclear ribonucleoprotein D0 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H2 Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoprotein L Heterogeneous nuclear ribonucleoprotein R, pseudogene 2 Heterogeneous nuclear ribonucleoprotein R Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoproteins A2/B1 Histone deacetylase complex subunit SAP18 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated Leukocyte receptor cluster member 1 Luc7-like protein Mago homolog B, exon junction complex subunit Mtr4 exosome RNA helicase NF-kappa-B-activating protein NFKB activating protein NHP2-like protein 1 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear speckle splicing regulatory protein 1 PHD finger-like domain-containing protein 5A PRKR interacting protein 1 Peptidyl-prolyl cis-trans isomerase-like 3 Peptidyl-prolyl cis-trans isomerase Peptidyl-prolyl cis-trans isomerase Peptidyl-prolyl cis-trans isomerase Peptidylprolyl isomerase domain and WD repeat containing 1 Pinin Pleiotropic regulator 1 Poly(U)-binding-splicing factor PUF60 Poly(rC) binding protein 1 Poly(rC) binding protein 2 Polyglutamine-binding protein 1 Polypyrimidine tract-binding protein 1 Pre-mRNA processing factor 40 homolog A Pre-mRNA processing factor 4 Pre-mRNA processing factor 8 Pre-mRNA-processing factor 19 Pre-mRNA-processing factor 6 Pre-mRNA-splicing factor 18 Pre-mRNA-splicing factor 38A Pre-mRNA-splicing factor CWC22 homolog Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor RBM22 Pre-mRNA-splicing factor SLU7 Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor SYF1 Pre-mRNA-splicing factor SYF2 Probable ATP-dependent RNA helicase DDX46 Probable ATP-dependent RNA helicase DDX5 Proline rich mitotic checkpoint control factor Protein BUD31 homolog Protein CASC3 Protein FAM32A Protein Red Protein mago nashi homolog RING-type E3 ubiquitin transferase RNA binding motif protein 25-like 1 RNA binding motif protein 25 RNA binding motif protein 39 RNA binding motif protein 7 RNA helicase RNA helicase RNA helicase RNA helicase RNA helicase RNA helicase RNA helicase RNA polymerase II subunit C RNA polymerase II subunit D RNA polymerase II subunit I RNA polymerase II subunit J RNA-binding motif protein, X chromosome RNA-binding motif protein, X-linked 2 RNA-binding protein 10 RNA-binding protein 42 RNA-binding protein 5 RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 RRM domain-containing protein SNW domain-containing protein 1 STING ER exit protein SURP and G-patch domain-containing protein 1 Serine and arginine repetitive matrix 1 Serine and arginine rich splicing factor 10 Serine and arginine rich splicing factor 11 Serine and arginine rich splicing factor 12 Serine and arginine rich splicing factor 3 Serine and arginine rich splicing factor 7 Serine and arginine rich splicing factor 8 Serine/arginine repetitive matrix 2 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 9 Serine/threonine-protein kinase PRP4 homolog Similar to human chromosome 9 open reading frame 78 Similar to microfibrillar-associated protein 1 Sm protein F Smad nuclear interacting protein 1 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein U5 subunit 40 Small nuclear ribonucleoprotein polypeptide A' Small nuclear ribonucleoprotein-associated protein B Small nuclear ribonucleoprotein-associated protein N Spliceosome RNA helicase Ddx39b Spliceosome-associated protein CWC15 homolog Splicing factor 1 Splicing factor 3A subunit 1 Splicing factor 3A subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3a, subunit 3 Splicing factor 3b, subunit 1 Splicing factor 3b, subunit 2 Splicing factor 45 Splicing factor Cactin Splicing factor U2AF 26 kDa subunit Splicing factor U2AF subunit Splicing factor YJU2 Survival of motor neuron-related-splicing factor 30 Transcription elongation regulator 1 Transformer-2 protein homolog beta U1 small nuclear ribonucleoprotein 70 kDa U1 small nuclear ribonucleoprotein A U1 small nuclear ribonucleoprotein C U2 small nuclear RNA auxiliary factor 1 U2 snRNP-associated SURP domain containing U4/U6 small nuclear ribonucleoprotein Prp31 U4/U6 small nuclear ribonucleoprotein Prp3 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein U4/U6.U5 tri-snRNP-associated protein 1 U5 small nuclear ribonucleoprotein 200 kDa helicase U6 snRNA-associated Sm-like protein LSm3 U6 snRNA-associated Sm-like protein LSm4 U6 snRNA-associated Sm-like protein LSm5 UBL fusion protein SDE2 UPF3B, regulator of nonsense mediated mRNA decay Ubiquitin-like protein 5 WD repeat-containing protein 70 WD40 repeat-containing protein SMU1 WW domain-binding protein 11 WW domain-binding protein 4 Y-box-binding protein 1 Zinc finger protein 830 histidine--tRNA ligase ubiquitinyl hydrolase 1	A0A0G2JTI7 A0A0G2JTM6 A0A0G2K283 A0A0G2K4P5 A0A0G2QC38 A0A0U1RRP3 A0A0U1RS26 A0A8I5Y5S4 A0A8I5ZK98 A0A8I5ZKV9 A0A8I5ZLP6 A0A8I5ZMN0 A0A8I5ZMR4 A0A8I5ZP60 A0A8I5ZQ92 A0A8I5ZR44 A0A8I5ZSN8 A0A8I5ZV21 A0A8I5ZV38 A0A8I5ZVI3 A0A8I5ZWC8 A0A8I5ZXP5 A0A8I5ZXU0 A0A8I6A2P1 A0A8I6A2X2 A0A8I6A2Y2 A0A8I6A5P0 A0A8I6A854 A0A8I6A8Y6 A0A8I6A9Y1 A0A8I6AB48 A0A8I6AB60 A0A8I6ABZ7 A0A8I6ACC7 A0A8I6AFZ5 A0A8I6AH91 A0A8I6AI37 A0A8I6AM26 A0A8I6AMZ5 A0A8I6APJ0 A0A8I6AUP1 A0A8I6AXL7 A0A8I6GJW5 A0A8I6GLQ3 A0A8I6GMR5 A0A8I6GMR8 A0A8J8XB26 A0A8J8XIU8 A1A5S1 A7VJC2 B0BMS9 B0BN49 B0BNE2 B1WC40 B2GUU0 B2GV05 B2GV41 B2RYA6 B2RYC1 B2RYG1 B2RZ74 B5DEP7 B5DFM8 D3ZAX5 D3ZAY8 D3ZCL3 D3ZD76 D3ZD97 D3ZER8 D3ZFB2 D3ZG07 D3ZGL5 D3ZKZ0 D3ZQI0 D3ZQM0 D3ZR17 D3ZSP1 D3ZTL0 D3ZVP6 D4A321 D4A5A6 D4A5T1 D4A6A2 D4A7J8 D4A7U6 D4A944 D4A997 D4AAT4 D4AEG3 E9PST5 E9PT66 F1LM66 F1LNJ2 F1LQ48 F1LSC3 F1LU70 F1M0X6 F7FHL6 G3V6H2 G3V7F6 G3V7T6 G3V8Y5 G3V9M1 G3V9M8 G3V9R8 M0RBB1 M0RBH0 M0RCG9 M0RCY0 O08837 O70454 O88828 P04256 P17136 P55770 P61980 P62489 P62961 P62997 P63018 P63155 P63164 P70501 P83871 Q00438 Q01750 Q09167 Q27W01 Q27W02 Q3B8Q2 Q3MHS2 Q4FZU3 Q4KLI4 Q4KLI7 Q4QQU1 Q4QQU6 Q4QRB2 Q4V7C9 Q4V7D7 Q4V898 Q4V8K2 Q566E4 Q56A27 Q5BJN8 Q5BJP2 Q5EB90 Q5EB92 Q5HZF2 Q5M9G6 Q5PPI1 Q5PQK2 Q5PQQ2 Q5RKH1 Q5U214 Q5XIW8 Q62780 Q63413 Q66HG8 Q68FU8 Q6AXT7 Q6AXT8 Q6AY02 Q6AY09 Q6AY96 Q6AYB3 Q6AYK1 Q6AYL5 Q6AYU2 Q6IMY8 Q6PCT5 Q6PDU1 Q794E4 Q7TP17 Q80ZG5 Q812D3 Q8K3X0 Q8VHV7 Q99M63 Q99PK0 Q9JJ54 Q9JKB8 Q9JMJ4 Q9WUC8 Q9WV25	AABR07026797.1 AABR07029847.1 AABR07065078.1 AC109542.1 Acin1 Alyref Ath55 Auf1 Bat1 Bat1a Bcas2 Bud13 Bud31 Bwd C3h9orf78 Cactin Casc3 Cbp20 Cbp80 Ccdc12 Ccdc16 Ccdc55 Cdc40 Cdc5l Cherp Cl-4 Crn Crnkl1 Ctnnbl1 Cwc15 Cwc22 Cwc25 Cyp10l Ddx23 Ddx39b Ddx42 Ddx46 Ddx48 Ddx5 Dhx15 Dhx35 Dhx38 Dhx8 Dhx9 Edg2 Eftud2 Eif4a3 Fam32a Fam50a Fblim1 Fus G10 Gpatch1 Gtf2f1 Gtf2f2 Hars2 Hel117 Hnrnp Hnrnpa1 Hnrnpa2b1 Hnrnpa3 Hnrnpc Hnrnpd Hnrnpf Hnrnph1 Hnrnph2 Hnrnpk Hnrnpl Hnrnpr Hnrnpr-ps2 Hnrnpu Hnrpa1 Hnrpa2b1 Hnrpc Hnrpd Hnrpf Hnrph Hnrph1 Hnrph2 Hnrpk Hnrpr Hnrpu Hrs Hsc70 Hsc73 Hspa8 Htatsf1 Ik Ini Isy1 Kcrf LOC100360750 LOC100910750 LOC100911361 LOC120096281 LOC120098305 LOC687679 LSM3 LSM4 LSM5 Leng1 Lsm3 Lsm4 Lsm5 Lsm5l1 Lsm6 Lsm6l1 Lsm7 Luc7l3 Magoh Magohb Mfap1al1 Mln51 Mtrex Ncbp1 Ncbp2 Nhp2l1 Nkap Nsrp1 Nsrp70 Otag12 Pcbp1 Pcbp2 Pcdc5rp Phf5a Plrg1 Pnn Polr2a Polr2b Polr2c Polr2d Polr2e Polr2f Polr2g Polr2i Polr2j Ppih Ppil1 Ppil2 Ppil3 Ppil4 Ppwd1 Pqbp1 Prcc Prkrip1 Prp18 Prp19 Prp4k Prpf18 Prpf19 Prpf3 Prpf31 Prpf38a Prpf4 Prpf40a Prpf4b Prpf6 Prpf8 Ptb Ptbp1 Puf60 Pybp RGD1305178 RGD1561590 RGD1563634 RGD1564148 Rap30 Rbm10 Rbm17 Rbm22 Rbm25 Rbm25l1 Rbm39 Rbm42 Rbm5 Rbm7 Rbm8 Rbm8a Rbmx Rbmx2 Rbmxrt Rnps1 SNRPD2 SNRPD3 Sap18 Sap18-ps1 Sart1 Sde2 Sf1 Sf3a1 Sf3a2 Sf3a3 Sf3b1 Sf3b2 Sf3b3 Sf3b4 Sf3b5 Sf4 Sfrs10 Sfrs2 Sfrs5 Sfrs9 Siahbp1 Sipp1 Slu7 Smn Smndc1 Smu1 Snip1 Snrnp200 Snrnp27 Snrnp40 Snrnp70 Snrpa Snrpa1 Snrpb Snrpc Snrpd2 Snrpd3 Snrpe Snrpepl2 Snrpf Snrpg Snrpgl1 Snrpn Snu13 Snw1 Spf30 Srrm1 Srrm2 Srrt Srsf1 Srsf10 Srsf11 Srsf12 Srsf2 Srsf3 Srsf5 Srsf7 Srsf8 Srsf9 Steep1 Sugp1 Syf1 Syf2 Tbfii Tcerg1 Tra2b U2af1 U2af1l4 U2af2 U2surp Uap56 Ubl5 Upf3b Usp39 Wbp11 Wbp4 Wdr70 Xab2 YJU2 Yb1 Ybx1 Yju2 Zfp830 Zmat2 Znf830	Rattus norvegicus (Norway rat)
RHO GTPases activate PKNs	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta 3-phosphoinositide-dependent protein kinase 1 M-phase inducer phosphatase Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 14A Protein phosphatase 1 regulatory subunit Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Stratifin Transforming protein RhoA	D3ZIC4 D4ADT2 G3V9A3 O08874 O55173 P35213 P61589 P61983 P62142 P62260 P62747 P63102 P68255 P68511 Q10728 Q63433 Q6RUV5 Q99MC0	Arha Arha2 Arhb Cdc25c Cpi Cpi17 Mbs Msfs1 Mypt1 Pak2 Pdk1 Pdpk1 Pkn Pkn1 Pkn2 Ppp1cb Ppp1r12a Ppp1r12b Ppp1r14a Prk1 Prk2 Prkcl1 Prkcl2 Rac Rac1 Rhoa Rhob Sfn Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 Cytochrome c domain-containing protein Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase copper chaperone COX11 Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6C-2 Cytochrome c oxidase subunit 7A2 like Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit Cytochrome c, somatic DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR GTP-binding protein Rheb Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Glutathione peroxidase 2 Glutathione reductase (Fragment) Hamartin Leucine-rich PPR motif-containing protein, mitochondrial Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Protein kinase AMP-activated non-catalytic subunit gamma 2 Protein kinase AMP-activated non-catalytic subunit gamma 3 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR, complex 1 Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase mTOR Sestrin 1 Sestrin 2 Sestrin 3 Similar to Cytochrome c, somatic Stratifin Surfeit locus protein 1 Synthesis of cytochrome C oxidase 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidine phosphorylase Translational activator of cytochrome c oxidase 1 Tuberin	A0A0G2K4P1 A0A0G2K8S8 A0A140UHX4 A0A8I5ZSY5 A0A8I5ZWG1 A0A8I6A0N4 A0A8I6A8X0 A0A8I6AAY1 A0A8I6ADH7 B2GUV6 B2RYT9 B2RZ38 D3Z8B0 D3ZDU2 D3ZF11 D3ZNJ0 D3ZXV2 D4A568 D4A5L9 D4A7E4 D4AD29 G3V985 G3V9A3 O89049 P00406 P05370 P05503 P05505 P10818 P10888 P11232 P11240 P11951 P12075 P13264 P28492 P35213 P35704 P42346 P47196 P47197 P49816 P54645 P61983 P62260 P62898 P63102 P68255 P68511 P70619 P80385 P80386 P80431 P80432 P80433 P83645 Q0D2L6 Q3B8Q3 Q5SGE0 Q5U204 Q5XFV8 Q62639 Q63484 Q63486 Q63487 Q63716 Q6P6V0 Q6P791 Q8VHZ9 Q9QXU2 Q9QZH4 Q9R063 Q9Z136 Q9Z2K5	AC128290.1 Akt1 Akt2 Akt3 Ampk1 COX2 Ccdc44 Coi Coii Coiii Cox11 Cox14 Cox16 Cox18 Cox4 Cox4a Cox4i1 Cox5a Cox5b Cox6a1 Cox6al Cox6b1 Cox6c Cox6c2 Cox7a2l Cox7b Cox7c Cox7c1 Cox8 Cox8a Cox8l Cycs Cycsl2 Cycsl3 Ddit4 ENSRNOG00000066475 Frap1 G6pd G6pdx Ga Gbl Gls Gls2 Gpi Gpx2 Gsr LOC120096563 LOC690675 Lamtor1 Lamtor3 Lamtor4 Lamtor5 Lrp157 Lrpprc Lst8 Map2k1ip1 Mlst8 Msfs1 Mt-co1 Mt-co2 Mt-co3 Mtco1 Mtco2 Mtco3 Mtor Prdx1 Prdx2 Prdx5 Prkaa1 Prkab1 Prkab2 Prkag1 Prkag2 Prkag3 RGD1562558 Raft1 Redd1 Rheb Rptor RragB Rraga Rragc Rragc_predicted Rragd Rtp801 Sco1 Sesn1 Sesn2 Sesn3 Sfn Slc38a9 Surf-1 Surf1 Taco1 Tdpx1 Tdpx2 Tigar Trxr1 Tsc1 Tsc2 Txn Txn1 Txnrd1 Tymp Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
Activation of BAD and translocation to mitochondria	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta Bcl2-associated agonist of cell death Calcineurin subunit B type 1 Serine/threonine-protein phosphatase Stratifin	E2CWF0 G3V9A3 O35147 P35213 P61983 P62260 P63100 P63102 P68255 P68511	Bad Cna2 Cnb Msfs1 Ppp3cc Ppp3r1 Sfn Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 M-phase inducer phosphatase Stratifin Wee1-like protein kinase	D4ADT2 G3V9A3 P30277 P35213 P39951 P61983 P62260 P63102 P68255 P68511 Q63802	Ccnb1 Cdc2 Cdc25c Cdc2a Cdk1 Cdkn1 Msfs1 Sfn Wee1 Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
Signaling by Hippo	14-3-3 protein beta/alpha 14-3-3 protein epsilon Angiomotin-like 1 Angiomotin-like protein 2 Angiomotin Caspase-3 Dishevelled segment polarity protein 2 MOB kinase activator 1A MOB kinase activator 1B Nephrocystin 4 Protein salvador homolog 1 Serine/threonine-protein kinase 3 Serine/threonine-protein kinase 4 Tight junction protein 2 Tight junction protein ZO-1 Transcriptional coactivator YAP1 WW and C2 domain containing 1 WW domain containing transcription regulator 1 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0G2JX94 A0A0G2K2P5 A0A0G2K4A8 A0A8I5Y7F3 A0A8I5YCB8 A0A8I5ZJB8 A0A8I6ALD4 A4V8B4 D3ZB71 F1M2K4 F1M6U0 G3V735 G3V9Y6 O54748 P35213 P55213 P62260 Q2EJA0 Q3T1J9 Q4V7E6	Amot Amotl1 Amotl2 Casp3 Cpp32 Dvl2 LOC100361515 Lats1 Lats2 Mob1a Mob1b Mobk1b Mobkl1b Mst2 Nphp4 Sav1 Stk3 Stk4 Tjp1 Tjp2 Ww45 Wwc1 Wwtr1 Yap Yap1 Yap65 Ywhab Ywhae	Rattus norvegicus (Norway rat)
Regulation of localization of FOXO transcription factors	14-3-3 protein beta/alpha 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta Forkhead box O3 Forkhead box O4 Forkhead box O6 Forkhead box protein O1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Stratifin	A0A8I6A2S2 D3ZBQ1 D4A433 G3V7R4 G3V9A3 P35213 P47196 P47197 P61983 P63102 P68255 Q63484	Akt1 Akt2 Akt3 Foxo1 Foxo1a Foxo3 Foxo4 Foxo6 Msfs1 Sfn Ywhab Ywhag Ywhaq Ywhaz	Rattus norvegicus (Norway rat)
Rap1 signalling	14-3-3 protein beta/alpha 14-3-3 protein zeta/delta RAF proto-oncogene serine/threonine-protein kinase RAP1 GTPase activating protein 2 RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 (Fragment) Rap1 GTPase-activating protein Ras-related protein Rap-1A Ras-related protein Rap-1b Signal-induced proliferation-associated 1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cGMP-dependent protein kinase	A0A8I6A9E8 A0A8I6AQM4 E9PSX8 F1LV89 P0C643 P11345 P27791 P35213 P62836 P63102 P68182 Q62636 Q9R1K8 Q9Z1C7 Q9Z1C8	AABR07006724.1 Cgef2 Epac Epac1 Epac2 Krev1 Msfs1 Pkacb Prkaca Prkacb Prkg1 Raf Raf1 Rap1a Rap1b Rap1gap Rap1gap2 Rapgef3 Rapgef4 Rasgrp Rasgrp1 Rasgrp2 Sipa1 Ywhab Ywhaz	Rattus norvegicus (Norway rat)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase 5'-3' exoribonuclease 1 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Exosome complex component RRP45 Exosome component 1 Exosome component 2 Exosome component 4 Exosome component 5 Exosome component 6 M7GpppN-mRNA hydrolase-like MAPK activated protein kinase 2 RAC-alpha serine/threonine-protein kinase Ribosomal RNA-processing protein 40 Ribosomal RNA-processing protein 42 Ribosomal RNA-processing protein 43 mRNA decay activator protein ZFP36L1	A0A0G2QC37 A0A8I5ZNY7 A0A8I6GHQ8 D3ZBP3 D3ZT51 D3ZW38 D4A4Y0 D4ABN8 D4AE80 D4AE98 F7EPZ4 M0RDC9 P17431 P35213 P47196 Q4QR75 Q80ZF4	Akt1 Brf1 Cmg1 Dcp1a Dcp2 Dis3 Exosc1 Exosc2 Exosc3 Exosc4 Exosc5 Exosc6 Exosc7 Exosc8 Exosc9 LOC103690064 LOC679140 Mapkapk2 Tis11b Xrn1 Ywhab Zfp36l1	Rattus norvegicus (Norway rat)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase 5'-3' exoribonuclease 1 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Exosome complex component RRP45 Exosome component 1 Exosome component 2 Exosome component 4 Exosome component 5 Exosome component 6 M7GpppN-mRNA hydrolase-like MAPK activated protein kinase 2 Ribosomal RNA-processing protein 40 Ribosomal RNA-processing protein 42 Ribosomal RNA-processing protein 43 Transportin 1 mRNA decay activator protein ZFP36	A0A0G2QC37 A0A8I5ZNY7 A0A8I6GHQ8 D3ZBP3 D3ZT51 D3ZW38 D4A4Y0 D4ABN8 D4AE80 D4AE98 F1LQP9 F7EPZ4 M0RDC9 P35213 P47973 Q4QR75 Q80ZF4	Dcp1a Dcp2 Dis3 Exosc1 Exosc2 Exosc3 Exosc4 Exosc5 Exosc6 Exosc7 Exosc8 Exosc9 LOC103690064 LOC679140 Mapkapk2 Tis11 Tnpo1 Ttp Xrn1 Ywhab Zfp36	Rattus norvegicus (Norway rat)

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