GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **476 - 500** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Chylomicron clearance	Apolipoprotein B-100 Apolipoprotein E Hepatic triacylglycerol lipase Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor	D3ZAR1 P02650 P07867 P35952 Q7TMA5	Apob Apoe Arh Ldlr Ldlrap1 Lipc	Rattus norvegicus (Norway rat)
Regulation of TLR by endogenous ligand	Apolipoprotein B-100 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Gasdermin D Gasdermin E High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 Lipopolysaccharide-binding protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 7 Toll-like receptor	A0A096MJ11 A0A0G2K6P4 A0A8I5Y7D7 A0A8I6AM21 A0A8I6GBU6 E9PTD9 E9PTL5 F1MAG0 G3V695 P02680 P06399 P14480 P35467 P50115 P50116 P63159 Q07969 Q56DL5 Q63313 Q63691 Q7TMA5 Q9QX05	Apob Cd14 Cd36 Fat Fga Fgb Fgg Gsdmd Gsdme Hmg-1 Hmg1 Hmgb1 Hmgb1-ps33 Hmgb1-ps4 Hmgb1l1 Hmgb1l2 Hmgb1l3 Hmgb1l5 LOC108349189 LOC108350839 Lbp Ly96 Mrp14 Mrp8 S100a1 S100a8 S100a9 Tlr1 Tlr2 Tlr4 Tlr6 Tlr7	Rattus norvegicus (Norway rat)
Platelet sensitization by LDL	Apolipoprotein B-100 Cytosolic phospholipase A2 LDL receptor related protein 8 Mitogen-activated protein kinase 14 Platelet endothelial cell adhesion molecule Protein phosphatase 2 scaffold subunit A alpha Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Tyrosine-protein kinase Fgr Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	A0A8I5ZMG6 A0A8I5ZRC2 A0A8I6A6K6 D3ZDI7 D3ZE75 P41499 P50393 P62716 P63331 P70618 P81718 Q3SWT0 Q4QQT4 Q5XI34 Q6P6U0 Q7TMA5 Q80W83	Apob Cpla2 Csbp1 Csbp2 Fgr LOC100909468 Lrp8 Mapk14 Pecam Pecam1 Pla2g4 Pla2g4a Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Ptph6 Ptpn11 Ptpn6	Rattus norvegicus (Norway rat)
Scavenging by Class H Receptors	Apolipoprotein B-100 SPARC Stabilin 1	A0A8I5Y895 P16975 Q7TMA5	Apob Sparc Stab1	Rattus norvegicus (Norway rat)
Transport of fatty acids	Apolipoprotein D Epididymal-specific lipocalin-12 Lipocalin 9 Long-chain fatty acid transport protein 1 long-chain-fatty-acid--CoA ligase long-chain-fatty-acid--CoA ligase von Ebner gland protein 1 von Ebner gland protein 2	A0A8I6ADK2 B3EY83 D4A2B8 G3V7V3 P20289 P23593 P41244 P97849	Apod Fatp Fatp1 Lcn12 Lcn9 Slc27a1 Slc27a4 Slc27a6 Vegp Vegp1 Vegp2	Rattus norvegicus (Norway rat)
Ligand-independent caspase activation via DCC	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Caspase-3 Caspase-9 Netrin receptor DCC	D3ZWA8 P55213 Q63155 Q9JHK1	Appl1 Casp3 Casp9 Cpp32 Dcc RNCASP9	Rattus norvegicus (Norway rat)
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src SH2B adapter protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 6	A0A8I6G3R2 D4A3T0 F1LM93 P05696 P21581 P62994 P81718 Q01621 Q07014 Q62844 Q63116 Q9WUD9 Q9Z200	Aps Ash Cbl Fyn Grb2 KIT Kit Kitl Kitlg Lck Lyn Mgf Pkca Prkca Ptph6 Ptpn6 Sh2b2 Sos1 Src Yes1	Rattus norvegicus (Norway rat)
FasL/ CD95L signaling	Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 6	P36940 Q63199 Q8R2E7 Q9JHX4	Apt1 Apt1Lg1 Casp8 Cd95l Fadd Fas Fasl Faslg Tnfrsf6 Tnfsf6	Rattus norvegicus (Norway rat)
Passive transport by Aquaporins	Aquaporin 10 Aquaporin-11 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin-7 Aquaporin-8 Aquaporin-9 Aquaporin Lens fiber major intrinsic protein (Fragment)	A0A8I6A7W7 D4A9T6 P09011 P29975 P34080 P47862 P47863 P47864 P56403 P56405 P56627 Q8CHM1	Aqp1 Aqp10 Aqp11 Aqp12a Aqp2 Aqp3 Aqp4 Aqp5 Aqp7 Aqp8 Aqp9 Chip28 LOC686596 Mip	Rattus norvegicus (Norway rat)
Vasopressin regulates renal water homeostasis via Aquaporins	Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma RAB11 family interacting protein 2 Ras-related protein Rab-11A Unconventional myosin-Vb Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A8I6A8W0 A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 P01186 P09456 P12368 P12369 P27791 P29975 P34080 P43425 P47862 P47863 P52287 P54311 P54313 P61954 P62494 P62882 P63077 P63219 P68182 P70569 P81377 Q00788 Q63803	Aqp1 Aqp2 Aqp3 Aqp4 Avp Avpr2 Chip28 Gnas Gnas1 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Myo5b Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b Rab11 Rab11a Rab11fip2	Rattus norvegicus (Norway rat)
SUMOylation of intracellular receptors	Androgen receptor Bile acid receptor E3 SUMO-protein ligase PIAS2 E3 SUMO-protein ligase PIAS3 Estrogen receptor Glucocorticoid receptor Histone deacetylase 4 Mineralocorticoid receptor Nuclear receptor subfamily 1 group I member 2 Nuclear receptor subfamily 5 group A member 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Peroxisome proliferator-activated receptor alpha Progesterone receptor Protein inhibitor of activated STAT, 1 Protein inhibitor of activated STAT, 4 RAR-related orphan receptor A Retinoic acid receptor RXR-alpha Retinoic acid receptor, alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A0G2JW78 A0A8I6A803 A0A8I6AJT7 B5DFF9 O70260 P06211 P06536 P13053 P15207 P18113 P22199 P37230 P50569 P61959 P63059 P63281 Q05343 Q5I0H3 Q5XIF4 Q62685 Q62735 Q62755 Q63449 Q6AZ28 Q99P99 Q9QWM1 Q9R1A7	Ar Bar C-erba-alpha Erba2 Esr Esr1 Estr Ftzf1 Fxr Grl Hdac4 Lxra Lxrb Miz1 Mlr Nr1a1 Nr1a2 Nr1c1 Nr1h2 Nr1h3 Nr1h4 Nr1i1 Nr1i2 Nr2b1 Nr3a1 Nr3c1 Nr3c2 Nr3c3 Nr3c4 Nr5a1 Nr5a2 Pgr Pias1 Pias2 Pias3 Pias4 Piasx Ppar Ppara Pxr Rara Rip14 Rora Rxra Smt3a Smt3h2 Sumo1 Sumo2 Sumo3 Thra Thrb Ubce9 Ube2i Vdr	Rattus norvegicus (Norway rat)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	Androgen receptor Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Lysine-specific histone demethylase Nuclear receptor coactivator 2 Serine/threonine-protein kinase N1 [histone H3]-trimethyl-L-lysine(9) demethylase	A0A0G2JXI9 A0A0G2K736 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A9UMV8 D3ZJ08 D3ZVK7 D3ZXP3 D4ACM0 F1LS62 G3V9C7 M0RBQ5 P0CC09 P15207 P62804 P84245 Q00729 Q63433 Q6LED0 Q9WUI9	Ar ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Kdm1a Kdm4c LOC100365043 LOC100910200 LOC120097726 LOC684797 Ncoa2 Nr3c4 Pkn Pkn1 Prk1 Prkcl1 Th2b Tif2	Rattus norvegicus (Norway rat)
COPI-dependent Golgi-to-ER retrograde traffic	ADP-ribosylation factor 1 ADP-ribosylation factor 3 ADP-ribosylation factor 4 ADP-ribosylation factor 5 ADP-ribosylation factor GTPase-activating protein 1 ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 Alpha-soluble NSF attachment protein Beta-soluble NSF attachment protein Centromere protein E Centromere/kinetochore protein zw10 homolog Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma-1 Coatomer subunit gamma-2 Coatomer subunit zeta Coatomer subunit zeta ER lumen protein-retaining receptor 1 ER lumen protein-retaining receptor 2 ER lumen protein-retaining receptor Gamma-soluble NSF attachment protein Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Kinesin family member 11 Kinesin family member 13B Kinesin family member 16B Kinesin family member 20B Kinesin family member 21A Kinesin family member 26A Kinesin family member 26B Kinesin family member 4A Kinesin family member 4B Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 3 Kinesin light chain 4 Kinesin light chain Kinesin-1 heavy chain Kinesin-associated protein 3 Kinesin-like protein KIF15 Kinesin-like protein KIF18B Kinesin-like protein KIF1A Kinesin-like protein KIF1B Kinesin-like protein KIF1C Kinesin-like protein KIF21B Kinesin-like protein KIF22 Kinesin-like protein KIF27 Kinesin-like protein KIF28P Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinesin-like protein KIF3C Kinesin-like protein KIFC1 Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein NBAS subunit of NRZ tethering complex RAD50 interactor 1 Rac GTPase-activating protein 1 Ras-related protein Rab-1A Ras-related protein Rab-1B Syntaxin-18 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Transmembrane emp24 domain-containing protein 3 Transmembrane emp24 domain-containing protein 7 Transmembrane emp24 domain-containing protein 9 Vesicle transport protein SEC20 Vesicle transport protein USE1 Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b	A0A0G2JW74 A0A0G2JWJ1 A0A0G2K0P1 A0A0G2K350 A0A0G2K857 A0A0G2K8Z9 A0A0U1RRT4 A0A8I5Y868 A0A8I5ZNF1 A0A8I5ZRP3 A0A8I5ZS98 A0A8I5ZVW2 A0A8I5ZVY6 A0A8I5ZY18 A0A8I6A1D9 A0A8I6A1N2 A0A8I6A7F9 A0A8I6AFD4 A0A8I6AM92 A0A8I6GLI2 D3ZCG2 D3ZI07 D3ZTX0 D3ZV60 D4A976 D4ABY2 D4ADC4 D4ADP9 E9PSJ3 E9PSL8 F1LPB5 F1LQZ3 F1M4A4 F1M5N7 F1M8X9 F8WLE0 G3V6Y3 O35142 O35787 O55165 O88658 P10536 P23514 P37285 P54921 P61206 P61751 P84079 P84083 P85969 Q2PQA9 Q3MID3 Q4AEF8 Q4KLL9 Q4KLN7 Q4KM74 Q4V8C2 Q569A6 Q5I0E7 Q5I0E8 Q5PQM2 Q5U305 Q5XI51 Q5XI63 Q62848 Q62909 Q63524 Q63584 Q66H80 Q68FW4 Q68G30 Q6AY25 Q6NYB7 Q6QLM7 Q7M6Z5 Q7TSP2 Q8VHI8 Q9QUL6 Q9WV63	Arcn1 Arf1 Arf1gap Arf3 Arf4 Arf5 Arfgap1 Arfgap2 Arfgap3 Bnip1 Cenpe Copa Copb Copb1 Copb2 Copd Cope Copg Copg1 Copg2 Copz1 Copz2 Erg1 Gbf1 Kdelr1 Kdelr2 Kdelr3 Khc Kif11 Kif12 Kif13b Kif15 Kif16b Kif18a Kif18b Kif19 Kif19a Kif1a Kif1b Kif1c Kif1d Kif2 Kif20b Kif21a Kif21b Kif22 Kif23 Kif26a Kif26b Kif27 Kif28p Kif2a Kif2b Kif2c Kif3a Kif3b Kif3c Kif4a Kif4b Kif5a Kif5b Kif6 Kif9 Kifap3 Kifc1 Kifc2 Klc Klc1 Klc2 Klc3 Klc4 Klp2 Klp6 Kns2 Knsl8 Krp1 Krp2 Napa Napb Napg Nbas Nsf Rab1 Rab1A Rab1b Racgap1 Rint1 Rnp24 Sec20l Sec22b Sec22l1 Snap Snapa Snapb Stx18 Tmed10 Tmed2 Tmed3 Tmed7 Tmed9 Tmp21 Use1 Zfp289 Znf289 Zw10	Rattus norvegicus (Norway rat)
Retrograde transport at the Trans-Golgi-Network	ADP-ribosylation factor-like protein 1 ADP-ribosylation factor-related protein 1 Alpha-soluble NSF attachment protein Arfaptin-2 Beta-soluble NSF attachment protein Cation-dependent mannose-6-phosphate receptor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 GRIP and coiled-coil domain containing 1 GRIP and coiled-coil domain-containing protein 2 Gamma-soluble NSF attachment protein Golgin A1 Golgin subfamily A member 4 Insulin-like growth factor 2 receptor Protein RIC1 homolog RAB6B, member RAS oncogene family RAB9B, member RAS oncogene family RGP1 homolog, RAB6A GEF complex partner 1 Rab9 effector protein with kelch motifs Ras-related protein Rab-43 Ras-related protein Rab-6A Ras-related protein Rab-9A Rho-related BTB domain containing 3 Short coiled-coil protein Syntaxin 16 Syntaxin-6 Sys1 golgi trafficking protein TATA element modulatory factor 1 Trans-Golgi network integral membrane protein TGN38 USP6 N-terminal like Vacuolar protein sorting-associated protein 51 homolog Vacuolar protein sorting-associated protein 52 homolog Vacuolar protein sorting-associated protein 53 homolog Vacuolar protein sorting-associated protein 54 Vesicle transport through interaction with t-SNAREs homolog 1A Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-fusing ATPase	A0A096MJ99 A0A0G2JT78 A0A0G2JZ48 A0A0G2K350 A0A0G2K528 A0A0G2K9P5 A0A8I5ZYV2 A0A8I6AFV4 A0A8I6AQS5 A0A8I6AU01 A0A8I6AXD4 A0A8I6GJ60 D3ZP15 D3ZPA1 D3ZT01 D3ZW90 D3ZZL9 D3ZZM3 D4A224 D4A6K4 F1M4I4 G3V824 O55166 P19814 P54921 P61212 P63025 P85969 Q3T1G7 Q4V8F4 Q53B90 Q5RJZ6 Q5U4E6 Q63055 Q63635 Q68FP9 Q6AY20 Q6AY65 Q99P75 Q9JI51 Q9JMK8 Q9QUL6 Q9WVB1	Are1 Arf7 Arfip2 Arfrp1 Arl1 Arp1 Cog1 Cog2 Cog3 Cog4 Cog5 Cog6 Cog7 Dbndd2 Erg1 Gcc1 Gcc185 Gcc2 Golga1 Golga4 Igf2r M6pr Napa Napb Napg Nsf RGD1310016 Rab43 Rab6 Rab6a Rab6b Rab9 Rab9a Rab9b Rabepk Rgp1 Rhobtb3 Ric1 Sacm2l Scoc Scoco Snap Snapa Snapb Stx16 Stx6 Syb3 Sys1 Tmf1 Ttgn1 Usp6nl Vamp3 Vamp4 Vps51 Vps52 Vps53 Vps54 Vps54l Vti1a Vti1l2	Rattus norvegicus (Norway rat)
EGFR downregulation	Amphiregulin Betacellulin Cell division control protein 42 homolog E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor pathway substrate 15-like 1 Epidermal growth factor receptor pathway substrate 15 Epsin-1 Growth factor receptor-bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Protein sprouty homolog 2 Protransforming growth factor alpha Receptor protein-tyrosine kinase Rho guanine nucleotide exchange factor 7 SH3 domain-containing kinase-binding protein 1 Signal transducing adapter molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I5YC99 A0A8I6A5Y3 A0A8I6A726 A0A8I6AQ55 A0A8I6G3R2 B5DF55 B5DFH3 F1LQQ5 G3V6K6 G3V7Q4 O35179 O35180 O35964 O55043 O88339 P01134 P07522 P0CG51 P24338 P62982 P62994 Q06175 Q5HZA2 Q5XHY7 Q63429 Q8CFN2 Q925Q9 Q9JJ50 Q9Z0L5	Areg Arhgef7 Ash Btc Cbl Cdc42 Dtr Egf Egfr Epn1 Eps15 Eps15l1 Ereg Grb2 Hbegf Hegfl Hgs Hrs Hrs2 LOC100360645 Pak3bp Pixb Ptpn12 Ptpn3 Rps27a Ruk Sdgf Seta Sh3d2a Sh3d2c1 Sh3gl1 Sh3gl2 Sh3gl3 Sh3kbp1 Sh3p13 Sh3p4 Sh3p8 Spry1 Spry2 Stam Stam2 Tgfa Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
GAB1 signalosome	Amphiregulin Betacellulin GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Receptor protein-tyrosine kinase Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6AQ55 D3ZAL7 G3V6K6 P01134 P07522 P24338 P32577 P41499 P62994 Q06175 Q63787 Q66H76 Q9JM80 Q9WUD9 Q9Z0L5	Areg Ash Btc Cbp Csk Dtr Egf Egfr Ereg Gab1 Grb2 Hbegf Hegfl Pag Pag1 Pik3ca Pik3r1 Ptpn11 Pxn Sdgf Src Tgfa	Rattus norvegicus (Norway rat)
SHC1 events in EGFR signaling	Amphiregulin Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6AQ55 D4A3T0 G3V6K6 P01134 P07522 P08644 P20171 P24338 P62994 Q04970 Q06175 Q5M824 Q9Z0L5	Areg Ash Btc Dtr Egf Egfr Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Nras Sdgf Shc1 Sos1 Tgfa	Rattus norvegicus (Norway rat)
GRB2 events in EGFR signaling	Amphiregulin Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6AQ55 D4A3T0 G3V6K6 P01134 P07522 P08644 P20171 P24338 P62994 Q04970 Q06175 Q9Z0L5	Areg Ash Btc Dtr Egf Egfr Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Nras Sdgf Sos1 Tgfa	Rattus norvegicus (Norway rat)
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Amphiregulin Betacellulin Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Receptor protein-tyrosine kinase	A0A8I6AQ55 G3V6K6 P01134 P07522 P10686 P24338 Q06175 Q9Z0L5	Areg Btc Dtr Egf Egfr Ereg Hbegf Hegfl Plcg1 Sdgf Tgfa	Rattus norvegicus (Norway rat)
Cargo concentration in the ER	Alpha-1-antiproteinase Amphiregulin CD59 glycoprotein Cathepsin Z Coagulation factor VIII Collagen type VII alpha 1 chain Cornichon family AMPA receptor auxiliary protein 1 Dipeptidyl peptidase 1 Folate receptor alpha Glutamate receptor 1 Golgi SNAP receptor complex member 2 Guanine nucleotide-exchange factor SEC12 Lectin, mannose-binding 2 MIA SH3 domain ER export factor 2 MIA SH3 domain ER export factor 3 Multiple coagulation factor deficiency protein 2 homolog Protein ERGIC-53-like Protein ERGIC-53 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein SEC23 Protransforming growth factor alpha SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Small COPII coat GTPase SAR1B Syntaxin-5 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Vesicle-trafficking protein SEC22b	A0A0G2JVM2 A0A0G2K112 A0A0G2K626 A0A8I5ZSK4 B5DFC3 D0Q0Y7 D3ZE04 D3ZEB1 D3ZW15 D3ZZA8 F7FPK8 G3V8M6 G3V9S9 O35165 P01134 P17475 P19490 P24338 P27274 P80067 Q08851 Q4KM74 Q5BJU5 Q5FB95 Q5HZY2 Q62902 Q63524 Q63584 Q8K5B3 Q9R1T3 Q9WTV0	Areg Cd59 Cnih1 Cnih2 Cnih3 Col7a1 Ctsc Ctsy Ctsz Ergic53 Ergl F8 Folr1 GluA1 Glur1 Gosr2 Gria1 Gs27 Lman1 Lman1l Lman2 Mcfd2 Mia2 Mia3 Preb Rnp24 Sar1b Sdgf Sdnsf Sec12 Sec22b Sec22l1 Sec23a Sec24a Sec24b Sec24c Sec24d Serpina1 Stx5 Stx5a Tgfa Tmed10 Tmed2 Tmp21	Rattus norvegicus (Norway rat)
Synthesis of PIPs at the Golgi membrane	1-phosphatidylinositol-3-phosphate 5-kinase ADP-ribosylation factor 1 ADP-ribosylation factor 3 Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase beta Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol polyphosphate 5-phosphatase type IV Phosphatidylinositol-3-phosphatase SAC1 Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphoinositide 3-kinase regulatory subunit 4 Protein VAC14 homolog Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2	A0A8I5YBG1 D3ZGS3 D3ZTF6 D4ADC8 O08561 O08662 O70173 O88763 P0C0R5 P61206 P84079 Q5XIL2 Q80W92 Q99M64 Q9ES21 Q9WVR1	Arf1 Arf3 Inpp5e Ocrl Pi4k2a Pi4k2b Pi4ka Pi4kb Pi4kii Pik3c2a Pik3c2g Pik3c3 Pik3r4 Pik4ca Pik4cb Pikfyve Sac1 Sacm1l Tpte Tpte2 Vac14 Vps34	Rattus norvegicus (Norway rat)
Synthesis of PIPs at the plasma membrane	ADP-ribosylation factor 1 Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase K Myotubularin related protein 14 Myotubularin-related protein 3 Myotubularin-related protein 6 Myotubularin Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase, regulatory subunit 6 Pleckstrin homology domain containing A1 Pleckstrin homology domain containing A2 Pleckstrin homology domain containing A5 Pleckstrin homology domain containing A6 Pleckstrin homology domain-containing family A member 4 Pleckstrin homology domain-containing family A member 8 RUN and FYVE domain containing 1 Ras-related protein Rab-14 Ras-related protein Rab-4A Ras-related protein Rab-5A Sesquipedalian Synaptojanin-1 Synaptojanin-2 Type II inositol 3,4-bisphosphate 4-phosphatase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 13 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2JXT6 A0A0G2K1A8 A0A0G2K1Q0 A0A0G2K2Z2 A0A0G2K344 A0A8I5Y1D5 A0A8I5Y949 A0A8I5ZTX1 A0A8I6AKY1 A0A8I6AU71 A0A8I6G5K9 A0A8I6G942 D3ZFJ0 D3ZGS3 D3ZMA2 D3ZSI8 D3ZTF6 D3ZY60 D4A4I3 E9PTG5 F1LR42 F1LVI0 G3V9S3 M0RC99 O55207 O70173 O88370 O88377 P05714 P60669 P61107 P84079 P97573 Q5CZZ9 Q5I6B8 Q5PQT2 Q5XIL2 Q62784 Q62910 Q63787 Q63788 Q63789 Q6AXQ4 Q99M64 Q9JMC1 Q9QWG5 Q9R0I8 Q9WVR3 Q9Z1L0	Arf1 Bmx Fapp2 Inpp4a Inpp4b Inpp5d Inpp5j Inpp5k Inppl1 Mtm1 Mtmr1 Mtmr14 Mtmr3 Mtmr6 Ocrl Pepp1 Pi4k2a Pi4k2b Pi4kii Pib5pa Pik3c2a Pik3c2b Pik3c2g Pik3ca Pik3cb Pik3cd Pik3cg Pik3r1 Pik3r2 Pik3r3 Pik3r5 Pik3r6 Pip4k2a Pip4k2b Pip4k2c Pip4ka Pip5k1a Pip5k1b Pip5k1c Pip5k2a Pip5k2b Pip5k2c Pipp Plekha1 Plekha2 Plekha3 Plekha4 Plekha5 Plekha6 Plekha8 Pten Ptpn13 Rab14 Rab4 Rab4a Rab5a Rufy1 Ship Ship1 Ship2 Synj1 Synj2	Rattus norvegicus (Norway rat)
trans-Golgi Network Vesicle Budding	ADP-ribosylation factor 1 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Synaptosomal-associated protein 23 Syntaxin-4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	F1M8X9 O70377 P63045 P84079 Q08850 Q9JHW5 Q9WUF4	Arf1 Gbf1 Snap23 Stx4 Stx4a Syb2 Sybl1 Vamp2 Vamp7 Vamp8	Rattus norvegicus (Norway rat)
VxPx cargo-targeting to cilium	ADP-ribosylation factor 4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Cyclic nucleotide-gated channel alpha-2 Cyclic nucleotide-gated channel alpha-4 Cyclic nucleotide-gated channel beta-1 Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Polycystin 1, transient receptor potential channel interacting Polycystin-2 Rab-3A-interacting protein Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	A0A0G2K2V5 A0A8I5ZN27 D4A5F1 F1M8X9 F1MAD3 O54921 O54922 O54923 O54924 P35280 P51489 P61751 P62494 P97878 Q00195 Q1AAU6 Q62739 Q62824 Q62825 Q64359	Arf4 Asap1 CNCG2 CNCG3L CNCG4 Cgn2 Cncg2 Cnga2 Cnga4 Cngb1 Ddef1 Exo70 Exo84 Exoc1 Exoc2 Exoc3 Exoc4 Exoc5 Exoc6 Exoc7 Exoc8 Gbf1 Pkd1 Pkd2 RCNC2 Rab11 Rab11a Rab3ip Rab8 Rab8a Rabin3 Rabin8 Rho Sec10l1 Sec15 Sec15a Sec15l1 Sec5 Sec5l1 Sec6 Sec6l1 Sec8 Sec8l1	Rattus norvegicus (Norway rat)
MET receptor recycling	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA3 Adapter molecule crk Crk-like protein GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Ras-related protein Rab-4A Ras-related protein Rab-4B	A0A0G2JV04 D3ZAL7 P05714 P17945 P51146 P62332 P62994 P97523 Q5U2U2 Q63768	Arf6 Ash Crk Crkl Crko Gab1 Gga3 Grb2 Hgf Met Rab4 Rab4a Rab4b	Rattus norvegicus (Norway rat)

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