GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **651 - 675** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Molecules associated with elastic fibres	Aa1018 Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphogenetic protein 7 EGF containing fibulin extracellular matrix protein 2 Fibulin 2 Fibulin-5 Growth differentiation factor 5 Integrin beta-1 Integrin beta-3 Integrin beta-6 Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Microfibril associated protein 2 Microfibril associated protein 4 Microfibril associated protein 5 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein	A0A0G2JVU1 A0A0G2K9S8 A0A8I5ZYG7 A0A8I6AQL1 A0A8I6AVC5 D3Z952 D4A7W8 D4A917 F1LZX9 F7F1E3 G3V6W8 G3V6X1 M0RAY4 O35806 P17246 P49001 P49134 Q00918 Q06826 Q07257 Q07258 Q4AEG6 Q6AYF4 Q7TQ11 Q8R2H2 Q9WVH8	Bmp-2 Bmp-4 Bmp10 Bmp2 Bmp4 Bmp7 Dance Dvr-4 Efemp2 Fbln2 Fbln5 Gdf5 Itga8 Itgav Itgb1 Itgb3 Itgb5 Itgb6 Itgb8 Ltbp1 Ltbp2 Ltbp3 Ltbp4 Mfap2 Mfap4 Mfap5 Tgf-b3 Tgfb1 Tgfb2 Tgfb3 Vtn	Rattus norvegicus (Norway rat)
Crosslinking of collagen fibrils	Lysyl oxidase homolog 2 Lysyl oxidase homolog Metalloendopeptidase Metalloendopeptidase Metalloendopeptidase Peroxidasin Procollagen C-endopeptidase enhancer 1 Protein-lysine 6-oxidase protein-lysine 6-oxidase protein-lysine 6-oxidase	A0A0G2JWB6 B5DF27 D3Z8U5 D3ZP82 D4A9V5 F1M280 F1M798 O08628 P16636 Q5FWS5	Bmp1 Lox Loxl1 Loxl2 Loxl3 Loxl4 Pcolce Pcpe1 Pxdn Tll1 Tll2	Rattus norvegicus (Norway rat)
Nitric oxide stimulates guanylate cyclase	Nitric oxide synthase 1 Nitric oxide synthase 3 Nitric oxide synthase, inducible	P29476 Q06518 Q62600	Bnos Nos1 Nos2 Nos3	Rattus norvegicus (Norway rat)
Organic anion transporters	Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial dicarboxylate carrier Mitochondrial glutamate carrier 1 Mitochondrial glutamate carrier 2 Sodium-coupled monocarboxylate transporter 1 Sodium-dependent phosphate transport protein 1 Sodium/iodide cotransporter Tricarboxylate transport protein, mitochondrial Vesicular glutamate transporter 1 Vesicular glutamate transporter 2 Vesicular glutamate transporter 3	A0A0G2K5L2 A0A8I6A218 O89035 P32089 P97700 Q505J6 Q62634 Q62795 Q63008 Q7TSF2 Q9JI12	Bnpi Dnpi Gc1 Nis Npt1 Slc17a1 Slc17a6 Slc17a7 Slc17a8 Slc20a3 Slc20a4 Slc25a1 Slc25a10 Slc25a11 Slc25a18 Slc25a22 Slc5a5 Slc5a8 Vglut1 Vglut2 Vglut3	Rattus norvegicus (Norway rat)
Glutathione synthesis and recycling	5-oxoprolinase Cytosolic non-specific dipeptidase Gamma-glutamyl cyclotransferase Glutamate--cysteine ligase catalytic subunit Glutamate--cysteine ligase regulatory subunit Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Glutathione synthetase Glutathione-specific gamma-glutamylcyclotransferase 1 Putative glutathione-specific gamma-glutamylcyclotransferase 2	B3STU3 D3ZPV8 P07314 P19468 P46413 P48508 P97608 Q641Z5 Q6IE08 Q6Q0N1 Q99MZ4 Q9QWE9	Botch Chac1 Chac2 Cndp2 Gclc Gclm Ggct Ggt Ggt1 Ggt5 Ggt6 Ggt7 Ggtl3 Ggtla1 Glclc Glclr Gss Npg7 Oplah	Rattus norvegicus (Norway rat)
Antimicrobial peptides	Anionic trypsin-2-like Anionic trypsin-2 BPI fold containing family B, member 2 BPI fold containing family B, member 6 BPI fold-containing family A member 1 BPI fold-containing family A member 2 BPI fold-containing family B member 1 BPI fold-containing family B member 4 Bactericidal permeability-increasing protein Cathelicidin antimicrobial peptide Cathepsin G Chromogranin-A Clusterin Elastase, neutrophil expressed Eosinophil-associated, ribonuclease A family, member 1 Eppin Intelectin 1 Lactotransferrin Liver-expressed antimicrobial peptide 2 Lysozyme C-1 Peptidoglycan recognition protein 1 Peptidoglycan recognition protein 2 Peptidoglycan recognition protein 4 Phospholipase A2, membrane associated Pre-eosinophil-associated ribonuclease-2 Proteinase 3 Regenerating islet-derived protein 3-alpha Regenerating islet-derived protein 3-beta Regenerating islet-derived protein 3-gamma Ribonuclease K6 Seminal vesicle secretory protein 3B Serine protease 1 Similar to Anionic trypsin II precursor (Pretrypsinogen II) Statherin Trypsin 10 trypsin trypsin	A0A8I5Y5M6 A0A8I5ZME9 A0A8I6AGK7 A0A8I6AKK4 A0A8I6APH4 A0A8I6ARE6 A0JPN3 D3ZAB1 D3ZAT0 D3ZQV0 D4A2Z2 D4A488 D4A5H4 D4AB30 D4AEA3 E9PT30 E9PU07 G3V8S9 M0R485 P00697 P00762 P00763 P05371 P10354 P14423 P17977 P25031 P35231 P42854 Q05704 Q5WN11 Q63471 Q6AXU0 Q6QDX6 Q8K4I4 Q9JLN4 W4VSR6	Bpi Bpifa1 Bpifa2 Bpifb1 Bpifb2 Bpifb4 Bpifb6 Camp Chga Clu Ctsg Ear1 Elane Eppin Itln1 LOC100361909 LOC100365995 LOC102554637 LOC299567 LOC474169 LOC683849 Leap2 Lplunc1 Lplunc4 Ltf Lyz Lyz1 Pap Pap1 Pap2 Pap3 Pglyrp Pglyrp1 Pglyrp2 Pglyrp4 Pgrp Pla2g2a Plunc Prss1 Prss2 Prss2l1 Prss3 Prtn3 Psp R15 Raf1 Raf4 Reg2 Reg3 Reg3a Reg3b Reg3g Rnase2 Rnase6 Ry2g5 Spinlw1 Stath Svs3b Trp1 Try1 Try10 Try2 Try4 Try5 Tryp1	Rattus norvegicus (Norway rat)	G49108TO
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Dynamin-2 Dynamin-3 Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain containing adaptor molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type	D3ZAS0 D3ZIP2 D3ZXR7 G3V6B9 P21575 P24135 P39052 Q08877 Q56DL5 Q63313 Q63691 Q6AXU0 Q9QX05	Bpi Cd14 Cd180 Dnm Dnm1 Dnm2 Dnm3 Dyn2 Dyn3 Lbp Ly86 Ly96 Plcg2 Ptpn4 Ticam2 Tlr4	Rattus norvegicus (Norway rat)
Frs2-mediated activation	14-3-3 protein beta/alpha Beta-nerve growth factor Crk-like protein Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibroblast growth factor receptor substrate 2 High affinity nerve growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Rap guanine nucleotide exchange factor 1 Ras-related protein Rap-1A non-specific serine/threonine protein kinase	A0A8I6ATH0 D4A244 F1M8L9 P21708 P25427 P35213 P35739 P36506 P62836 P63086 Q01986 Q5U2U2	Braf Crkl Erk1 Erk2 Frs2 Krev1 Map2k1 Map2k2 Mapk Mapk1 Mapk3 Mek1 Mek2 Mkk2 Ngf Ngfb Ntrk1 Prkm1 Prkm3 Prkmk1 Prkmk2 Rap1a Rapgef1 Trk Trka Ywhab	Rattus norvegicus (Norway rat)
Negative feedback regulation of MAPK pathway	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase non-specific serine/threonine protein kinase	A0A8I6ATH0 P11345 P21708 P36506 P63086 Q01986	Braf Erk1 Erk2 Map2k1 Map2k2 Mapk Mapk1 Mapk3 Mek1 Mek2 Mkk2 Prkm1 Prkm3 Prkmk1 Prkmk2 Raf Raf1	Rattus norvegicus (Norway rat)
Proton-coupled monocarboxylate transport	Basigin Embigin Monocarboxylate transporter 1 Monocarboxylate transporter 2 Monocarboxylate transporter 3 Monocarboxylate transporter 4	O35910 O70461 O88775 P26453 P53987 Q63344	Bsg Emb Gp70 Mct1 Mct2 Mct3 Mct4 Slc16a1 Slc16a3 Slc16a7 Slc16a8	Rattus norvegicus (Norway rat)
Nicotinate metabolism	5'-nucleotidase ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Glutamine-dependent NAD(+) synthetase NAD kinase 2, mitochondrial NAD(+) kinase Nicotinamide riboside kinase 1 Nicotinamide-nucleotide adenylyltransferase Nicotinamide-nucleotide adenylyltransferase Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Nicotinate-nucleotide pyrophosphorylase [carboxylating]	A0A8I5ZV91 A0A8I6AFT7 F7F588 P21588 Q0HA29 Q1HCL7 Q5I0M2 Q63072 Q64244 Q6AY91 Q812E8	Bst1 Cd38 Mnadk Nadk Nadk2 Nadkd1 Nadsyn1 Nmnat1 Nmnat2 Nmnat3 Nmrk1 Nrk1 Nt5 Nt5e Nte Qns1 Qprt	Rattus norvegicus (Norway rat)
Signaling by ERBB2	Betacellulin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Yes	A0A8I5Y1H8 A0A8I6AQ55 F1LM93 G3V6K6 O35569 P06494 P07522 P43322 P82995 Q06175 Q62799 Q62844 Q63692 Q9WUD9 Q9Z0L5	Btc Cdc37 Dtr Egf Egfr Erbb2 Erbb3 Ereg Fyn Hbegf Hegfl Hsp86 Hsp90aa1 Hspca Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Src Yes1	Rattus norvegicus (Norway rat)
SHC1 events in ERBB2 signaling	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 SHC-transforming protein 1 Tyrosine-protein phosphatase non-receptor type 12	A0A8I5Y1H8 A0A8I6AQ55 G3V6K6 G3V7Q4 O35569 P05696 P06494 P07522 P09215 P09216 P43322 Q06175 Q5M824 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Pkca Pkcd Pkce Prkca Prkcd Prkce Ptpn12 Shc1	Rattus norvegicus (Norway rat)
ERBB2 Activates PTK6 Signaling	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein kinase	A0A8I5Y1H8 A0A8I6AQ55 D3ZDS3 G3V6K6 O35569 P06494 P07522 P43322 Q06175 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Ptk6	Rattus norvegicus (Norway rat)
Signaling by ERBB4	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-3	A0A8I5Y1H8 A0A8I6AQ55 G3V6K6 O35569 P07522 P43322 Q06175 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb3 Ereg Hbegf Hegfl Ndf Nrg1 Nrg2 Nrg3 Ntak	Rattus norvegicus (Norway rat)
PI3K events in ERBB4 signaling	Betacellulin Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor	A0A0G2K344 A0A8I5Y1H8 A0A8I6AQ55 O35569 P43322 Q06175 Q63787 Q9Z0L5	Btc Dtr Ereg Hbegf Hegfl Ndf Nrg1 Nrg2 Nrg3 Ntak Pik3ca Pik3r1	Rattus norvegicus (Norway rat)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	CCR4-NOT transcription complex subunit 10 CCR4-NOT transcription complex subunit 11 CCR4-NOT transcription complex subunit 6 CCR4-NOT transcription complex subunit 9 CCR4-NOT transcription complex, subunit 1 CCR4-NOT transcription complex, subunit 2 CCR4-NOT transcription complex, subunit 3 CCR4-NOT transcription complex, subunit 4 Centromere protein J M-phase inducer phosphatase Nucleophosmin Protein BTG2 Serine/threonine-protein kinase PLK2 Serine/threonine-protein kinase PLK3 Tankyrase 1 binding protein 1 poly(A)-specific ribonuclease	A0A8I6AJD1 A0A8I6AL98 B0BNA9 D3ZF26 D3ZUV9 D4A194 D4ADT2 G3V7M0 P13084 P27049 Q498M7 Q5PQL2 Q5XIA4 Q6AXU9 Q9R011 Q9R012	Btg2 Ccr4 Cdc25c Cenpj Cnk Cnot1 Cnot10 Cnot11 Cnot2 Cnot3 Cnot4 Cnot6 Cnot6l Cnot9 Fnk Npm1 Pc3 Plk2 Plk3 Rcd1 Rqcd1 Snk Tnks1bp1	Rattus norvegicus (Norway rat)
Butyrophilin (BTN) family interactions	Butyrophilin, subfamily 1, member A1 Butyrophilin, subfamily 2, member A2 Butyrophilin-like 9 Butyrophilin-like protein 2 CD209a molecule Periplakin Xanthine dehydrogenase/oxidase	D3ZP17 D4A076 D4A5T8 F1LRV5 M0R7E0 P22985 Q6MG97	Btn1a1 Btn2a2 Btnl2 Btnl9 Cd209a LOC684480 Ppl Xdh	Rattus norvegicus (Norway rat)
SCF-beta-TrCP mediated degradation of Emi1	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cell division cycle protein 20 homolog Cullin 1 Fizzy and cell division cycle 20 related 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6G2R1 B0BN93 B1WCA1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q62623 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Cdc20 Cul1 Fzr1 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Interleukin-1 signaling	Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 E3 ubiquitin-protein ligase pellino homolog Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor accessory protein Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-1 receptor-associated kinase 3 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Polyubiquitin-B Polyubiquitin-C RELA proto-oncogene, NF-kB subunit Ring-box 1 S-phase kinase-associated protein 1 Sequestosome-1 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Toll-interacting protein Ubiquitin B-like Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eS31 fusion protein mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase	A0A0G2JUC8 A0A0G2JYX9 A0A0U1RRU5 A0A8I5Y0H0 A0A8I5ZMV7 A0A8I6A3Q1 A0A8I6A5Y3 A0A8I6ABN5 A0A8I6AH74 A0A8I6ANR6 A0A8I6G1H3 A0A8I6G2R1 A2RUW1 B2RYC8 B5DF45 D3ZSK3 O08623 P0C8E4 P0CG51 P16598 P25086 P43303 P62982 Q02955 Q4QQS0 Q5U303 Q63264 Q63429 Q63621 Q63746 Q6PEC4 Q6TMG5 Q6Y1S1 Q925D6 Q9QY78	Btrc Chuk Cul1 ENSRNOG00000067007 Ikba Ikbkb Ikbkg Ikkb Il-1r2 Il-1ra Il1a Il1b Il1r1 Il1r2 Il1ra Il1rap Il1rb Il1rn Irak1 Irak2 Irak3 Irak4 LOC100360645 Map2k6 Map3k7 Map3k7ip2 Mkk6 Myd88 Nemo Nfkbia Peli2 Rbx1 Rela Rps27a Skp1 Skp1a Sqstm1 Tab1 Tab2 Tab3 Tollip Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Zip	Rattus norvegicus (Norway rat)
Dectin-1 mediated noncanonical NF-kB signaling	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit Nuclear factor kappa B subunit 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta RELB proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-conjugating enzyme E2M Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZYZ8 A0A8I6A5Y3 A0A8I6ANR6 A0A8I6G2R1 A0A8I6G6F3 A0A8I6GIW9 B0BN93 D3ZTD1 D4A8H1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q99MI7 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Chuk Cul1 Fbxw11 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Map3k14 Mecl1 Mss1 Nfkb2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Relb Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba3 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube1c Ube2m	Rattus norvegicus (Norway rat)
NIK-->noncanonical NF-kB signaling	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit Nuclear factor kappa B subunit 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta RELB proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-conjugating enzyme E2M Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZYZ8 A0A8I6A5Y3 A0A8I6ANR6 A0A8I6G2R1 A0A8I6G6F3 A0A8I6GIW9 B0BN93 D3ZTD1 D4A8H1 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q99MI7 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Chuk Cul1 Fbxw11 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Map3k14 Mecl1 Mss1 Nfkb2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Relb Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba3 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube1c Ube2m	Rattus norvegicus (Norway rat)
GLI3 is processed to GLI3R by the proteasome	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Casein kinase I isoform alpha Cullin 1 GLI family zinc finger 3 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6A606 A0A8I6G2R1 B0BN93 F1LMQ3 F1LMZ8 F1M6I7 F1M9H1 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18266 P18420 P18421 P18422 P21670 P27791 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 P68182 P97633 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Csnk1a1 Cul1 Gli3 Gsk3b LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Pkacb Prkaca Prkacb Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sufu Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Prolactin receptor signaling	Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 Growth hormone receptor Prolactin receptor Prolactin Ring-box 1 S-phase kinase-associated protein 1 SH2B adapter protein 1 Somatotropin Tyrosine-protein kinase JAK2	A0A0G2JUC8 A0A8I5Y0H0 A0A8I6G2R1 P01237 P01244 P05710 P16310 Q62689 Q62985 Q6PEC4	Btrc Cul1 Gh Gh1 Ghr Jak2 Prl Prlr Rbx1 Sh2-b Sh2b1 Sh2bpsm1 Skp1 Skp1a	Rattus norvegicus (Norway rat)
Degradation of GLI1 by the proteasome	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 E3 ubiquitin-protein ligase GLI family zinc finger 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein numb homolog Ring-box 1 S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZZU1 A0A8I6A5Y3 A0A8I6A606 A0A8I6G2R1 B0BN93 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V6X8 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q2LC84 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Btrc Cul1 Gli1 Itch LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Numb Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Sufu Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)

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