GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **751 - 775** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
Regulation of cholesterol biosynthesis by SREBP (SREBF)	GTP-binding nuclear protein Ran Importin subunit beta-1 Membrane-bound transcription factor site-1 protease Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol regulatory element-binding protein cleavage-activating protein	A2RRU4 P52296 P56720 P62828 Q3T1I5 Q9WTZ3	Kpnb1 Mbtps1 Ran S1p Scap Ski1 Srebf1 Srebf2 Srebp1	Rattus norvegicus (Norway rat)
Electric Transmission Across Gap Junctions	Gap junction delta-2 protein Gap junction gamma-1 protein Gap junction protein Pannexin-1 Pannexin-2	A4GG66 F1LPI3 O70610 P60570 P60571	Gja10 Gja7 Gja9 Gjc1 Gjd2 Panx1 Panx2 Px1 Px2	Rattus norvegicus (Norway rat)
Ca activated K+ channels	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-activated potassium channel subunit beta-2 Calcium-activated potassium channel subunit beta-3 Calcium-activated potassium channel subunit beta-4 Intermediate conductance calcium-activated potassium channel protein 4 Small conductance calcium-activated potassium channel protein 1 Small conductance calcium-activated potassium channel protein 2 Small conductance calcium-activated potassium channel protein 3	A7VL23 P70604 P70605 P70606 P97678 Q62976 Q811Q0 Q9ESK8 Q9QYW1	Ik1 Kcnma Kcnma1 Kcnmb1 Kcnmb2 Kcnmb3 Kcnmb4 Kcnn1 Kcnn2 Kcnn3 Kcnn4 Sk1 Sk4 Smik	Rattus norvegicus (Norway rat)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor 7 PYD and CARD domain containing Pannexin-1 Proline-serine-threonine phosphatase-interacting protein 1 Protein SGT1 homolog Pyrin Thioredoxin-interacting protein Thioredoxin	B0BN85 B0BNK4 D4A523 G3V8L1 P11232 P34058 P60570 Q5M7W1 Q64663 Q9JJ25	Hsp84 Hsp90ab1 Hspc3 Hspcb Mefv Nlrp3 P2rx7 Panx1 Pstpip1 Px1 Pycard Sugt1 Txn Txn1 Txnip Vdup1	Rattus norvegicus (Norway rat)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin-like phospholipase domain containing 6	B0BND0 M0R715 Q9JL55	Enpp6 Gde1 Mir16 Pnpla6	Rattus norvegicus (Norway rat)
Acyl chain remodelling of PC	85/88 kDa calcium-independent phospholipase A2 Calcium-independent phospholipase A2-gamma Cytosolic phospholipase A2 Group 10 secretory phospholipase A2 Lysophosphatidylcholine acyltransferase 1 Lysophosphatidylcholine acyltransferase 2 Lysophosphatidylcholine acyltransferase 4 Lysophospholipid acyltransferase 2 Lysophospholipid acyltransferase 5 Lysoplasmalogenase TMEM86B Phospholipase A and acyltransferase 3 Phospholipase A2 group IVC Phospholipase A2 group V Phospholipase A2, group III Phospholipase A2, group XIIA Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Phospholipase B1, membrane-associated Secretory phospholipase A2 receptor	B0BNF0 B0K018 D3Z9B7 D3ZGN6 D3ZLB5 D3ZQH6 D3ZR52 D3ZRC4 D4A1I6 F1LMQ4 F1LPY6 F1M495 F7F420 O54728 P04055 P0C1Q3 P14423 P50393 P51433 P53817 P97570 Q1HAQ0 Q3T1J2 Q5FVN0 Q5U2V4 Q9QZT3	Aytl1 Aytl1a Aytl2 Cpla2 Grcc3f H-rev107 Hrasls3 Hrev107 Lpcat1 Lpcat2 Lpcat2a Lpcat3 Lpcat4 Mboat2 Mboat5 Oact2 Oact5 Phlpb Pla2g10 Pla2g12a Pla2g16 Pla2g1b Pla2g2a Pla2g2d Pla2g2f Pla2g3 Pla2g4 Pla2g4a Pla2g4b Pla2g4c Pla2g4d Pla2g4e Pla2g4f Pla2g5 Pla2g6 Pla2r1 Plaat3 Plb1 Plbd1 Pnpla8 Pnpla9 Rlp-3 Tmem86b	Rattus norvegicus (Norway rat)
Erythrocytes take up carbon dioxide and release oxygen	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Cytochrome b5 reductase 4 Hemoglobin subunit alpha-1/2 Hemoglobin subunit beta-1 NADH-cytochrome b5 reductase 1 NADH-cytochrome b5 reductase 2 cytochrome-b5 reductase	B0BNN3 D3ZZ05 P01946 P02091 P23562 P27139 P29975 P48284 Q5EB81 Q68EJ0 Q6AY12 Q7TNK7	Ae1 Aqp1 Ca1 Ca2 Ca4 Car1 Chip28 Cyb5r1 Cyb5r2 Cyb5r4 Cyb5rl Hba-a1 Hba1 Hbb Ncb5or Rh50 Rhag Slc4a1	Rattus norvegicus (Norway rat)
Erythrocytes take up oxygen and release carbon dioxide	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Hemoglobin subunit alpha-1/2 Hemoglobin subunit beta-1	B0BNN3 P01946 P02091 P23562 P27139 P29975 P48284 Q7TNK7	Ae1 Aqp1 Ca1 Ca2 Ca4 Car1 Chip28 Hba-a1 Hba1 Hbb Rh50 Rhag Slc4a1	Rattus norvegicus (Norway rat)
Acyl chain remodelling of PI	Cytosolic phospholipase A2 Group 10 secretory phospholipase A2 Phospholipase A and acyltransferase 3 Phospholipase A2 group IVC Phospholipase A2 group V Phospholipase A2, group XIIA Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor	B0K018 D3Z9B7 D3ZLB5 D3ZQH6 F1LMQ4 F1LPY6 F1M495 F7F420 P04055 P14423 P50393 P51433 P53817 Q5U2V4 Q9QZT3	Cpla2 H-rev107 Hrasls3 Hrev107 Pla2g10 Pla2g12a Pla2g16 Pla2g1b Pla2g2a Pla2g2d Pla2g2f Pla2g4 Pla2g4a Pla2g4c Pla2g4d Pla2g4e Pla2g4f Pla2g5 Pla2r1 Plaat3 Plbd1 Rlp-3	Rattus norvegicus (Norway rat)
Non-integrin membrane-ECM interactions	Epithelial discoidin domain-containing receptor 1 receptor protein-tyrosine kinase	B1WC09 Q63474	Ddr1 Ddr2 Eddr1 Ptk3	Rattus norvegicus (Norway rat)
Cytosolic sulfonation of small molecules	3'(2'),5'-bisphosphate nucleotidase 1 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase Podocalyxin-like 2 Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2 Putative protein-lysine deacylase ABHD14B Sulfotransferase 1A1 Sulfotransferase 1B1 Sulfotransferase 1C2 Sulfotransferase 2A1 Sulfotransferase 2A2 Sulfotransferase 2A6 Sulfotransferase 2B1 Sulfotransferase 4A1 Sulfotransferase	B1WC18 D4AD37 M0R952 P15709 P17988 P22789 P50235 P52847 P63047 Q29YR5 Q3KR92 Q5RJS8 Q6DGG1 Q9WUW8 Q9Z1N4	Abhd14b Bpnt1 Bpnt2 Impa3 Impad1 Podxl2 Sal3 Smp2a St1a1 St1b1 St2a1 St2a2 Sult1a1 Sult1b1 Sult1c2 Sult2a1 Sult2a2 Sult2a6 Sult2b1 Sult4a1 Sult6b1 Sultk1 Sultx3 Tpst1 Tpst2	Rattus norvegicus (Norway rat)
Synthesis of PS	Phosphatidylserine synthase 1 Phosphatidylserine synthase 2	B2GV22 Q5PQL5	Ptdss1 Ptdss2	Rattus norvegicus (Norway rat)
Free fatty acid receptors	Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3	B2GV46 Q76EI6 Q8K3T4	Ffar1 Ffar2 Ffar3 Gpr40 Gpr41 Gpr43	Rattus norvegicus (Norway rat)
Synthesis of UDP-N-acetyl-glucosamine	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 N-acetyl-D-glucosamine kinase N-acetylglucosamine-6-phosphate deacetylase N-acylglucosamine 2-epimerase Phosphoacetylglucosamine mutase UDP-N-acetylglucosamine pyrophosphorylase 1	B2RYN0 D3ZF39 P51607 P81799 P82808 Q4KMC4 Q5BJY6	Amdhd2 Gfpt1 Gfpt2 Nagk Pgm3 Renbp Uap1	Rattus norvegicus (Norway rat)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2 protein-ribulosamine 3-kinase protein-ribulosamine 3-kinase	B2RYN1 D3ZEB1 D3ZZU8 Q3KR92 Q5RJS8 Q9WVM4	F8 Fn3k Fn3krp Icmt Tpst1 Tpst2	Rattus norvegicus (Norway rat)
DCC mediated attractive signaling	Cell division control protein 42 homolog Cytoplasmic protein Focal adhesion kinase 1 Netrin receptor DCC Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 Triple functional domain protein Tyrosine-protein kinase Fyn	B2RZ33 F1M0Z1 O35346 Q62844 Q63155 Q6RUV5 Q8CFN2 Q9WUD9	Cdc42 Dcc Fak Fak1 Fyn Nck1 Ptk2 Rac Rac1 Src Trio	Rattus norvegicus (Norway rat)
Glutathione synthesis and recycling	5-oxoprolinase Cytosolic non-specific dipeptidase Gamma-glutamyl cyclotransferase Glutamate--cysteine ligase catalytic subunit Glutamate--cysteine ligase regulatory subunit Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Glutathione synthetase Glutathione-specific gamma-glutamylcyclotransferase 1 Putative glutathione-specific gamma-glutamylcyclotransferase 2	B3STU3 D3ZPV8 P07314 P19468 P46413 P48508 P97608 Q641Z5 Q6IE08 Q6Q0N1 Q99MZ4 Q9QWE9	Botch Chac1 Chac2 Cndp2 Gclc Gclm Ggct Ggt Ggt1 Ggt5 Ggt6 Ggt7 Ggtl3 Ggtla1 Glclc Glclr Gss Npg7 Oplah	Rattus norvegicus (Norway rat)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6 Toll/interleukin-1 receptor domain-containing adapter protein	B5DF45 D3ZXA5 Q5XIC2 Q62925	Ecsit Map3k1 Mekk Mekk1 Tirap Traf6	Rattus norvegicus (Norway rat)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	B5DF45 Q5XIC2 Q62925	Ecsit Map3k1 Mekk Mekk1 Traf6	Rattus norvegicus (Norway rat)
MyD88 cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	B5DF45 Q5XIC2 Q62925	Ecsit Map3k1 Mekk Mekk1 Traf6	Rattus norvegicus (Norway rat)
RHOBTB3 ATPase cycle	5-hydroxytryptamine receptor 7 Cullin-3 G1/S-specific cyclin-E1 Hepatocyte growth factor-regulated tyrosine kinase substrate Leucine-rich repeat-containing protein 41 RAB9B, member RAS oncogene family Ras-related protein Rab-9A Rho-related BTB domain containing 3 von Hippel-Lindau disease tumor suppressor	B5DF89 D3ZP15 D3ZW90 P32305 P39949 Q5M9H1 Q64259 Q99P75 Q9JJ50	Ccne Ccne1 Cul3 Hgs Hrs Hrs2 Htr7 Lrrc41 Rab9 Rab9a Rab9b Rhobtb3 Vhl	Rattus norvegicus (Norway rat)
Peptide ligand-binding receptors	Adrenocorticotropic hormone receptor Angiotensinogen Apelin receptor Apelin B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 C5a anaphylatoxin chemotactic receptor 2 Cholecystokinin receptor type A Cholecystokinin Complement C3 Complement C5 Delta-type opioid receptor Endoplasmic reticulum membrane adapter protein XK Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 G-protein coupled estrogen receptor 1 G-protein coupled receptor 37-like 1 Galanin peptides Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3 Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Kappa-type opioid receptor Kell metallo-endopeptidase (Kell blood group) KiSS-1 receptor Kininogen-1 Melanin-concentrating hormone receptor 1 Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Metastasis-suppressor KiSS-1 Mu-type opioid receptor Neurolysin, mitochondrial Neuromedin B Neuromedin-B receptor Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide B Neuropeptide S receptor Neuropeptide S Neuropeptide W Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 4 Neuropeptide Y receptor type 5 Neuropeptides B/W receptor type 1 Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Nociceptin receptor Pancreatic polypeptide prohormone Peptide YY Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Pro-thyrotropin-releasing hormone Proenkephalin-A Proenkephalin-B Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Prolactin-releasing peptide receptor Prolactin-releasing peptide Prosaposin receptor GPR37 Prosaposin Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor A Type-2 angiotensin II receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B endothelin-converting enzyme 1	B6ZGR5 D4A1W6 D4A4U1 F1M761 G3V848 O08726 O08878 O55197 O88626 P01015 P01026 P01150 P01194 P01355 P04094 P06300 P06303 P07808 P08650 P08934 P0C0L6 P0C0P7 P10631 P10683 P10960 P12760 P13207 P14200 P18292 P20068 P20789 P21451 P21555 P22388 P23943 P24053 P24393 P25023 P25095 P26684 P26824 P28646 P30551 P30553 P30680 P30936 P30937 P30938 P32244 P33533 P33535 P34975 P35345 P35351 P35370 P42676 P42893 P49684 P52500 P60042 P70596 P81278 P97520 P97583 P97639 Q01717 Q56UD9 Q5GH61 Q5H8A2 Q62805 Q62923 Q63384 Q63447 Q63634 Q63645 Q64121 Q695P6 Q765I2 Q7TSB7 Q8K1M5 Q8K418 Q8K4P2 Q8R413 Q8R414 Q8R415 Q8R416 Q920E0 Q920E1 Q924U1 Q9ESQ4 Q9JHG3 Q9JJI5 Q9QYC5 Q9QYC6 Q9QZQ4 Q9R0R3	Agt Agtr1 Agtr1a Agtr2 Agtrl1 Apel Apj Apln Aplnr At1a B1bkr Bdkrb1 Bdkrb2 Bkr Brs3 Bv8 C3 C3ar1 C5 C5ar1 C5ar2 C5l2 C5r1 Cck Cckar Cckbr Cmkrl2 Ece1 Ece2 Edn1 Edn2 Edn3 Ednra Ednrb Etbrlp2 F2 F2r F2rl1 F2rl2 F2rl3 Gal Galn Galnr Galnr1 Galnr2 Galnr3 Galr1 Galr2 Galr3 Gper Gper1 Gpr10 Gpr14 Gpr154 Gpr24 Gpr30 Gpr37 Gpr37l1 Gpr41 Gpr54 Gpr66 Gpr7 Gpr73 Gpr73l1 Gpr77 Grp Grpr Kel Kiss1 Kiss1r Kng Kng1 Mc1r Mc2r Mc3r Mc4r Mc5r Mch Mchr1 Nln Nmb Nmbr Nms Nmu Nmur1 Nmur2 Npb Npbwr1 Nps Npsr1 Npw Npy Npy1r Npy4r Npy5r Npyr5 Ntr2 Nts Ntsr Ntsr1 Ntsr2 Oor Oprd1 Oprk1 Oprl Oprl1 Oprm1 Par1 Par2 Par3 Par4 Pdyn Penk Penk-rs Penk1 Pkr1 Pkr2 Pmch Pnoc Pomc Pomc2 Ppl8 Ppy Ppyr1 Prh Prlh Prlhr Prok1 Prok2 Prokr1 Prokr2 Psap Pyy Ror-a Ror-b Ror-d Senr Serpina8 Sgp1 Slc1 Smst Sst Sstr1 Sstr2 Sstr3 Sstr4 Sstr5 Tgr1 Trh Trhr Urp Uts2 Uts2b Uts2d Uts2r Xk Xkh Xkr1 Xrg1	Rattus norvegicus (Norway rat)
Triglyceride catabolism	Fatty acid-binding protein 12 Fatty acid-binding protein 5 Fatty acid-binding protein 9 Fatty acid-binding protein, adipocyte Fatty acid-binding protein, brain Fatty acid-binding protein, heart Fatty acid-binding protein, intestinal Fatty acid-binding protein, liver Gastrotropin Glycerol-3-phosphate dehydrogenase, mitochondrial Patatin like phospholipase domain containing 4 Patatin-like phospholipase domain containing 5	B7SUM8 D3ZXU1 D4A227 P02692 P02693 P07483 P35571 P55051 P55053 P55054 P70623 P80020	Blbp FABP12 Fabp1 Fabp2 Fabp3 Fabp4 Fabp5 Fabp6 Fabp7 Fabp9 Fabpi Gpd2 Ilbp Illbp Perf15 Pnpla4 Pnpla5 RGD1562200	Rattus norvegicus (Norway rat)
Nucleotide catabolism	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	D3Z898	Samhd1	Rattus norvegicus (Norway rat)
betaKlotho-mediated ligand binding	Fibroblast growth factor receptor 4 Fibroblast growth factor Klotho beta	D3Z8T6 Q498D6 Q8VI81	FGF15 Fgf19 Fgf8a Fgfr4 Klb	Rattus norvegicus (Norway rat)

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