GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **801 - 825** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼
Arachidonic acid metabolism	Acyltransferase Cytosolic phospholipase A2 Fatty-acid amide hydrolase 1	D3ZVA9 P50393 P97612	Awat1 Cpla2 Faah Faah1 Pla2g4 Pla2g4a	Rattus norvegicus (Norway rat)
Activation of RAC1 downstream of NMDARs	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type 1 Calmodulin-3	O88831 P0DP31 P97756 Q63450	CaMIII Calm3 Cam3 Camc Camk1 Camkk1 Camkk2	Rattus norvegicus (Norway rat)
Cellular response to hypoxia	Endothelial PAS domain-containing protein 1 Hypoxia inducible factor 1 subunit alpha inhibitor Hypoxia-inducible factor 1-alpha	F7F9I0 O35800 Q9JHS1	Epas1 Hif1a Hif1an Hif2a	Rattus norvegicus (Norway rat)
FasL/ CD95L signaling	Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 6	P36940 Q63199 Q8R2E7 Q9JHX4	Apt1 Apt1Lg1 Casp8 Cd95l Fadd Fas Fasl Faslg Tnfrsf6 Tnfsf6	Rattus norvegicus (Norway rat)
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P25427 P35739	Ngf Ngfb Ntrk1 Trk Trka	Rattus norvegicus (Norway rat)
Transport of organic anions	Monocarboxylate transporter 8 Solute carrier organic anion transporter family member 1A4 Solute carrier organic anion transporter family member 1B2 Solute carrier organic anion transporter family member 1C1 Solute carrier organic anion transporter family member 2A1 Solute carrier organic anion transporter family member 2B1 Solute carrier organic anion transporter family member 3A1 Solute carrier organic anion transporter family member 4A1 Solute carrier organic anion transporter family member 4C1 Vasopressin-neurophysin 2-copeptin	O35913 P01186 Q00910 Q71MB6 Q8K1P8 Q99N01 Q99N02 Q9EPZ7 Q9JHI3 Q9QZX8	Avp Bsat1 Matr1 Mct8 Oatp1a4 Oatp1b2 Oatp1c1 Oatp2 Oatp2b1 Oatp3a1 Oatp4a1 Oatp4c1 Oatpd Oatpe Oatpf Pgt2 SLC16A2 Slc21a10 Slc21a11 Slc21a12 Slc21a14 Slc21a2 Slc21a20 Slc21a5 Slc21a9 Slco1a4 Slco1b2 Slco1c1 Slco2a1 Slco2b1 Slco3a1 Slco4a1 Slco4c1	Rattus norvegicus (Norway rat)
Lysosome Vesicle Biogenesis	ADP-ribosylation factor 1 AP complex subunit beta AP complex subunit sigma AP complex subunit sigma AP complex subunit sigma AP-1 complex subunit beta-1 AP-1 complex subunit gamma AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-4 complex subunit epsilon AP-4 complex subunit mu-1 Adaptor related protein complex 1 subunit sigma 1 Amyloid-beta precursor protein Beta-arrestin-1 Biogenesis of lysosome-related organelles complex 1 subunit 1 Cathepsin Z Cation-dependent mannose-6-phosphate receptor Charged multivesicular body protein 2a Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Clavesin-1 Clavesin-2 Deoxyribonuclease-2-alpha DnaJ heat shock protein family (Hsp40) member C6 Dynamin-2 Endophilin-A1 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate N-acetylglucosamine-6-sulfatase Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 protein disulfide-isomerase	A0A0G2K410 A0A8I5Y697 A0A8I5ZVG9 A0A8I5ZY10 A0A8I6A896 A0A8I6AAZ1 A0A8I6AMT9 A6JFQ6 A6JUQ6 D3ZGW2 D3ZKU7 D3ZRP6 D3ZX21 D3ZZC1 F7EZ57 O35179 P08081 P08082 P08592 P11442 P29066 P39052 P52303 P63018 P63045 P84079 Q2PWT8 Q32KJ5 Q32Q06 Q6AY20 Q9JHW5 Q9JJ50 Q9QZK8 Q9R1T3 Q9WUF4	A4 AD1 Adtb1 Ap1b1 Ap1g1 Ap1g2 Ap1m1 Ap1m2 Ap1s1 Ap1s2 Ap1s3 Ap4b1 Ap4e1 Ap4m1 Ap4s1 App Arf1 Arrb1 Bloc1s1 Chmp2a Clta Cltb Cltc Clvs1 Clvs2 Ctsy Ctsz Dnajc6 Dnase2 Dnase2a Dnl2 Dnm2 Dyn2 Gns Hgs Hrs Hrs2 Hsc70 Hsc73 Hspa8 M6pr Rlbp1l1 Rlbp1l2 Sh3d2a Sh3gl2 Sh3p4 Syb2 Sybl1 Txndc5 Vamp2 Vamp7 Vamp8	Rattus norvegicus (Norway rat)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	Cell division cycle protein 20 homolog Mitotic arrest deficient 2 like 1	D4ACM2 Q62623	Cdc20 Mad2l1	Rattus norvegicus (Norway rat)
Gap junction degradation	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein Unconventional myosin-VI	A0A8I6ACM8 O88797 P08050 P08081 P08082 P11442 P21575 P39052 P84092	Ap2m1 Clta Cltb Cltc Cxn-43 Dab2 Dnm Dnm1 Dnm2 Doc2 Dyn2 Gja1 Myo6	Rattus norvegicus (Norway rat)
Glutamate and glutamine metabolism	Aspartate aminotransferase, mitochondrial Delta-1-pyrroline-5-carboxylate synthase Glutamate dehydrogenase 1, mitochondrial Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Glutamine synthetase Kynurenine--oxoglutarate transaminase 1 N-acetylaspartylglutamate synthase N-acetylaspartylglutamate synthase Ornithine aminotransferase, mitochondrial Pyrroline-5-carboxylate reductase 2 Pyrroline-5-carboxylate reductase 3 Pyrroline-5-carboxylate reductase	A0A8I6A4B6 A0A8I6AAN3 D3ZXI0 D4A7C3 P00507 P04182 P09606 P10860 P13264 P28492 Q08415 Q5PQJ6 Q6AY23	Aldh18a1 Ccbl1 Ga Glns Gls Gls2 Glud Glud1 Glul Got2 Kat Kyat1 Maat Oat Pycr1 Pycr2 Pycr3 Pycrl Rimkla Rimklb	Rattus norvegicus (Norway rat)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Cystathionine gamma-lyase Cysteine dioxygenase type 1 Flavin-containing monooxygenase 1 Glutamate decarboxylase-like 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	A0A8I5ZWY4 A0A8I6AWC8 P18757 P21816 P24329 P36365 P97532 P97615	Ado Cdo1 Cth Fmo-1 Fmo1 Gadl1 Mpst Trx2 Tst Txn2	Rattus norvegicus (Norway rat)
NOTCH4 Activation and Transmission of Signal to the Nucleus	14-3-3 protein zeta/delta	P63102	Msfs1 Ywhaz	Rattus norvegicus (Norway rat)
Downregulation of ERBB2 signaling	Betacellulin Cullin-5 Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Megakaryocyte-associated tyrosine-protein kinase Neuregulin 3 Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein phosphatase non-receptor type 12 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A8I5Y1H8 A0A8I6A5Y3 A0A8I6AHV1 A0A8I6AQ55 G3V6K6 G3V7Q4 O35569 P06494 P07522 P0CG51 P41243 P43322 P62982 P82995 Q06175 Q62799 Q63429 Q63692 Q9JJ31 Q9Z0L5	Batk Btc Cdc37 Ctk Cul5 Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Hsp86 Hsp90aa1 Hspca LOC100360645 Matk Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Ptpn12 Ptpn18 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vacm1	Rattus norvegicus (Norway rat)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 M-phase inducer phosphatase 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Serine/threonine-protein kinase Chk1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 B0BN93 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P48965 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q91ZN7 Q9JHW0 Q9WTV5 Q9Z2X3	Cdc25a Chek1 Chk1 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ring12 Rps27a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Lysine catabolism	2-oxoadipate dehydrogenase complex component E1 5-phosphohydroxy-L-lysine phospho-lyase Alpha-aminoadipic semialdehyde dehydrogenase Alpha-aminoadipic semialdehyde synthase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glutaryl-CoA dehydrogenase, mitochondrial Hydroxylysine kinase Ketimine reductase mu-crystallin Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Mitochondrial 2-oxodicarboxylate carrier sarcosine oxidasee (formaldehyde-forming)	A0A8I5Y5E0 A0A8I5ZN89 A0A8J8XD81 A2VCW9 Q01205 Q4KLP0 Q5I0K1 Q64057 Q64602 Q6P6R2 Q99JD3 Q9QYU4	Aadat Aass Ald7a1 Aldh7a1 Crym Dhtkd1 Dld Dlst Gcdh Hykk Kat2 LOC103690164 Odc Phykpl Pipox Slc25a21	Rattus norvegicus (Norway rat)
Neddylation	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Ankrd9 protein Ankyrin repeat and SOCS box containing 11 Ankyrin repeat and SOCS box containing 15 Ankyrin repeat and SOCS box protein 14 Ankyrin repeat and SOCS box protein 17 Ankyrin repeat and SOCS box protein 8 Ankyrin repeat and SOCS box-containing 12 Ankyrin repeat and SOCS box-containing 13 Ankyrin repeat and SOCS box-containing 16 Ankyrin repeat and SOCS box-containing 18 Ankyrin repeat and SOCS box-containing 1 Ankyrin repeat and SOCS box-containing 4 Ankyrin repeat and SOCS box-containing 5 Ankyrin repeat and SOCS box-containing 6 Ankyrin repeat and SOCS box-containing 7 Ankyrin repeat and SOCS box-containing 9 BTB (POZ) domain containing 1 BTB domain containing 6 BTB/POZ domain-containing protein KCTD7 Baculoviral IAP repeat-containing protein 5 Beta-transducin repeat containing E3 ubiquitin protein ligase COMM domain containing 10 COMM domain containing 2 COMM domain containing 4 COMM domain containing 7 COMM domain containing 8 COMM domain containing 9 COMM domain-containing protein 1 COMM domain-containing protein 3 COMM domain-containing protein 5 COMM domain-containing protein 6 COP1, E3 ubiquitin ligase COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 8 COP9 signalosome subunit 5 COP9 signalosome subunit 7A COP9 signalosome subunit 7B Coiled-coil domain-containing protein 22 Coiled-coil domain-containing protein 8 Cullin 1 Cullin 2 Cullin 4A Cullin 4B Cullin 9 Cullin-3 Cullin-5 Cullin-7 Cullin-associated NEDD8-dissociated protein 1 Cyclin-F Cytokine-inducible SH2-containing protein (Fragment) DCN1-like protein 3 DCN1-like protein 5 DCN1-like protein DCN1-like protein DDB1 and CUL4 associated factor 13 DDB1 and CUL4 associated factor 4 DDB1 and CUL4 associated factor 5 DDB1 and CUL4 associated factor 6 DDB1- and CUL4-associated factor 10 DDB1- and CUL4-associated factor 11 DDB1- and CUL4-associated factor 17 DDB1- and CUL4-associated factor 8 DET1- and DDB1-associated protein 1 DNA damage-binding protein 1 DNA damage-binding protein 2 Defective in cullin neddylation 1 domain containing 2 Denticleless E3 ubiquitin protein ligase homolog Elongin-B Elongin-C Endothelial PAS domain-containing protein 1 F-box and WD repeat domain containing 10 F-box and WD repeat domain containing 11 F-box and WD repeat domain containing 4 F-box and WD repeat domain containing 9 F-box and WD-40 domain protein 17 F-box and leucine-rich repeat protein 18 F-box and leucine-rich repeat protein 19 F-box and leucine-rich repeat protein 21 F-box and leucine-rich repeat protein 3 F-box and leucine-rich repeat protein 4 F-box and leucine-rich repeat protein 7 F-box only protein 11 F-box only protein 17 F-box only protein 30 F-box only protein 31 F-box only protein 32 F-box only protein 6 F-box only protein 7 F-box only protein 9 F-box protein 10 F-box protein 15 F-box protein 21 F-box protein 22 F-box protein 27 F-box protein 2 F-box protein 40 F-box protein 41 F-box protein 44 F-box protein 4 F-box/LRR-repeat protein 15 F-box/LRR-repeat protein 16 F-box/LRR-repeat protein 5 F-box/WD repeat-containing protein 2 F-box/WD repeat-containing protein 5 F-box/WD repeat-containing protein 7 F-box/WD repeat-containing protein 8 Fem-1 homolog C Gigaxonin Histone-binding protein RBBP7 Hypoxia-inducible factor 1-alpha Hypoxia-inducible factor 3-alpha Kelch repeat and BTB domain containing 7 Kelch repeat and BTB domain-containing protein 8 Kelch-like ECH-associated protein 1 Kelch-like family member 11 Kelch-like family member 13 Kelch-like family member 5 Kelch-like protein 20 Kelch-like protein 21 Kelch-like protein 22 Kelch-like protein 25 Kelch-like protein 2 Kelch-like protein 3 Kelch-like protein 41 LIM domain 7 Leucine rich repeat protein 1 Leucine-rich repeat-containing protein 41 NEDD8-activating enzyme E1 catalytic subunit NEDD8-activating enzyme E1 regulatory subunit NEDD8-conjugating enzyme UBE2F NEDD8 Negative regulator of ubiquitin-like proteins 1 Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Obscurin-like protein 1 Polyubiquitin-B Polyubiquitin-C Potassium channel tetramerization domain containing 6 Promyelocytic leukemia zinc finger protein Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein fem-1 homolog A Protein fem-1 homolog B RB binding protein 5, histone lysine methyltransferase complex subunit RING-type E3 ubiquitin transferase Ring finger protein 7 Ring-box 1 S-phase kinase associated protein 2 S-phase kinase-associated protein 1 SPRY domain-containing SOCS box protein 2 SPRY domain-containing SOCS box protein 3 Sentrin-specific protease 8 SplA/ryanodine receptor domain and SOCS box containing 4 Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 5 Suppressor of cytokine signaling 6 TUB like protein 4 Transitional endoplasmic reticulum ATPase UBX domain protein 7 Ubiquitin B-like Ubiquitin D Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2M Ubiquitin-ribosomal protein eS31 fusion protein WD and tetratricopeptide repeats 1 WD repeat and SOCS box-containing 2 WD repeat-containing protein 5 von Hippel-Lindau disease tumor suppressor	A0A096UWG1 A0A0G2JSL0 A0A0G2JTC9 A0A0G2JUC8 A0A0G2JWD3 A0A0G2JY40 A0A0G2K652 A0A0G2K8R3 A0A0G2K9A9 A0A0G2KAX0 A0A0G2KB30 A0A1B0GWU1 A0A8I5XVT7 A0A8I5Y0H0 A0A8I5Y4X4 A0A8I5Y8A6 A0A8I5YBR2 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZQH9 A0A8I5ZQV9 A0A8I5ZSR2 A0A8I5ZSV2 A0A8I5ZYZ4 A0A8I5ZYZ8 A0A8I6A381 A0A8I6A5I4 A0A8I6A5Y3 A0A8I6A9Y7 A0A8I6AAB1 A0A8I6AAL1 A0A8I6AMP0 A0A8I6ANG1 A0A8I6AT07 A0A8I6G2R1 A0A8I6G6G2 A0A8I6G8I6 A0A8I6GIW9 A0A8I6GJZ3 A0A8J8XZ77 B0BN93 B0K015 B1H285 B1H299 B1WBR8 B1WC97 B2RYN2 B2RZ17 B5DF38 B5DF89 D3Z8N4 D3Z8N7 D3Z902 D3Z9G1 D3ZC01 D3ZDK2 D3ZE86 D3ZEF4 D3ZEJ6 D3ZER4 D3ZFM2 D3ZIH4 D3ZK73 D3ZLN7 D3ZPJ1 D3ZR08 D3ZRI9 D3ZS84 D3ZU52 D3ZU92 D3ZUE4 D3ZVU8 D3ZZ80 D3ZZC3 D3ZZR4 D4A1H7 D4A2K4 D4A2V7 D4A6R1 D4A7F7 D4A7Z0 D4A8E5 D4A8E7 D4A8G6 D4A8I5 D4ABB4 D4AD48 D4AED2 F1LM44 F1LMQ3 F1LMZ8 F1LXQ1 F1LZ52 F1LZF0 F1M5Q6 F1M6I7 F1M6U5 F1M6W6 F1M7P1 F1M7U0 F1M9V9 F1MAA2 F1MAM1 F7EM85 F7EUU4 F7F1S8 F7FBG3 F7FGV7 F7FNG5 G3V6K4 G3V6W6 G3V6Z2 G3V8G2 G3V9P4 M0R9B9 M0RA85 O35800 O54968 O70512 O88582 O88583 O88761 P0C6P7 P0C927 P0CG51 P0DL28 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P46462 P48004 P57790 P60901 P61078 P61203 P62193 P62198 P62521 P62839 P62870 P62982 P83941 P86182 P97536 P97834 Q32Q00 Q498M4 Q4FZT9 Q4KLI9 Q4KLM4 Q4KM35 Q4V890 Q4V8B2 Q4V8E2 Q5FVJ8 Q5M877 Q5M9G8 Q5M9H1 Q5MJ12 Q5PPL2 Q5RKI2 Q5S3S9 Q5U203 Q5U2M6 Q5U2X1 Q5XI67 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q64259 Q68FS2 Q68FS3 Q68FW9 Q6AY27 Q6J757 Q6P4Z9 Q6P755 Q6P9U3 Q6PEC4 Q71UE8 Q71UF4 Q7TSL3 Q8CHM6 Q8K4F8 Q91Y78 Q91Z62 Q921A3 Q923V4 Q99MI7 Q9ER30 Q9ERR2 Q9ES53 Q9ES54 Q9ESW0 Q9JHS1 Q9JHS2 Q9JHW0 Q9JHY7 Q9JJ31 Q9WTV5 Q9Z1A5 Q9Z2X3	AABR07002848.1 AABR07034438.1 Ankrd9 Appbp1 Asb-4 Asb1 Asb11 Asb12 Asb13 Asb14 Asb15 Asb16 Asb17 Asb18 Asb4 Asb5 Asb6 Asb7 Asb8 Asb9 Birc5 Btbd1 Btbd6 Btrc Cand1 Ccdc22 Ccdc8 Ccnf Cish Cish2 Cish3 Commd1 Commd10 Commd2 Commd3 Commd4 Commd5 Commd6 Commd7 Commd8 Commd9 Cop1 Cops1 Cops2 Cops3 Cops4 Cops5 Cops6 Cops7a Cops7b Cops8 Csn1 Csn2 Csn3 Csn4 Csn8 Cul1 Cul2 Cul3 Cul4a Cul4b Cul5 Cul7 Cul9 Dcaf10 Dcaf11 Dcaf13 Dcaf17 Dcaf4 Dcaf5 Dcaf6 Dcaf8 Dcun1d1 Dcun1d2 Dcun1d3 Dcun1d4 Dcun1d5 Dda1 Ddb1 Ddb2 Dtl Elob Eloc Epas1 Fat10 Fbg2 Fbs2 Fbxl15 Fbxl16 Fbxl18 Fbxl18l1 Fbxl19 Fbxl21 Fbxl3 Fbxl4 Fbxl5 Fbxl7 Fbxo10 Fbxo11 Fbxo15 Fbxo17 Fbxo2 Fbxo21 Fbxo22 Fbxo27 Fbxo30 Fbxo31 Fbxo32 Fbxo4 Fbxo40 Fbxo41 Fbxo44 Fbxo6 Fbxo6b Fbxo7 Fbxo9 Fbxw10 Fbxw11 Fbxw17 Fbxw2 Fbxw4 Fbxw5 Fbxw7 Fbxw8 Fbxw9 Fem1a Fem1b Fem1c Gan Gps1 Hif1a Hif2a Hif3a Inrf2 Kbtbd10 Kbtbd7 Kbtbd8 Kctd6 Kctd7 Keap1 Klhl11 Klhl13 Klhl2 Klhl20 Klhl21 Klhl22 Klhl25 Klhl3 Klhl41 Klhl5 Krp1 LOC100360645 LOC100360846 LOC100365869 Lmo7 Lmp10 Lmp2 Lrr1 Lrrc41 Mecl1 Mss1 Mul1 Nae1 Nedd8 Nfe2l2 Npl4 Nploc4 Nrf2 Nub1 Obsl1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbbp5 Rbbp7 Rbx1 Rfwd2 Ring12 Rnf7 Rps27a Scirr1 Senp8 Skp1 Skp1a Skp2 Socs2 Socs3 Socs5 Socs6 Spsb2 Spsb3 Spsb4 Ssb2 Sug1 Tbp1 Tbp7 Tceb1 Tceb2 Tip120 Tip120a Trip15 Tulp4 Uba3 Uba80 Ubb Ubbl1 Ubc Ubc4 Ubcep1 Ubch4 Ubch5b Ubcl1 Ubd Ube1c Ube2d1 Ube2d2 Ube2d3 Ube2f Ube2m Uchl3 Ufd1 Ufd1l Vacm1 Vcp Vhl Wdr23 Wdr42a Wdr5 Wdtc1 Wsb2 Zbtb16 Zfp145	Rattus norvegicus (Norway rat)
Activated NTRK3 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 NT-3 growth factor receptor Neurotrophin-3	P10686 P18280 Q03351	Ntf-3 Ntf3 Ntrk3 Plcg1 Trkc	Rattus norvegicus (Norway rat)
Retrograde transport at the Trans-Golgi-Network	ADP-ribosylation factor-like protein 1 ADP-ribosylation factor-related protein 1 Alpha-soluble NSF attachment protein Arfaptin-2 Beta-soluble NSF attachment protein Cation-dependent mannose-6-phosphate receptor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 GRIP and coiled-coil domain containing 1 GRIP and coiled-coil domain-containing protein 2 Gamma-soluble NSF attachment protein Golgin A1 Golgin subfamily A member 4 Insulin-like growth factor 2 receptor Protein RIC1 homolog RAB6B, member RAS oncogene family RAB9B, member RAS oncogene family RGP1 homolog, RAB6A GEF complex partner 1 Rab9 effector protein with kelch motifs Ras-related protein Rab-43 Ras-related protein Rab-6A Ras-related protein Rab-9A Rho-related BTB domain containing 3 Short coiled-coil protein Syntaxin 16 Syntaxin-6 Sys1 golgi trafficking protein TATA element modulatory factor 1 Trans-Golgi network integral membrane protein TGN38 USP6 N-terminal like Vacuolar protein sorting-associated protein 51 homolog Vacuolar protein sorting-associated protein 52 homolog Vacuolar protein sorting-associated protein 53 homolog Vacuolar protein sorting-associated protein 54 Vesicle transport through interaction with t-SNAREs homolog 1A Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-fusing ATPase	A0A096MJ99 A0A0G2JT78 A0A0G2JZ48 A0A0G2K350 A0A0G2K528 A0A0G2K9P5 A0A8I5ZYV2 A0A8I6AFV4 A0A8I6AQS5 A0A8I6AU01 A0A8I6AXD4 A0A8I6GJ60 D3ZP15 D3ZPA1 D3ZT01 D3ZW90 D3ZZL9 D3ZZM3 D4A224 D4A6K4 F1M4I4 G3V824 O55166 P19814 P54921 P61212 P63025 P85969 Q3T1G7 Q4V8F4 Q53B90 Q5RJZ6 Q5U4E6 Q63055 Q63635 Q68FP9 Q6AY20 Q6AY65 Q99P75 Q9JI51 Q9JMK8 Q9QUL6 Q9WVB1	Are1 Arf7 Arfip2 Arfrp1 Arl1 Arp1 Cog1 Cog2 Cog3 Cog4 Cog5 Cog6 Cog7 Dbndd2 Erg1 Gcc1 Gcc185 Gcc2 Golga1 Golga4 Igf2r M6pr Napa Napb Napg Nsf RGD1310016 Rab43 Rab6 Rab6a Rab6b Rab9 Rab9a Rab9b Rabepk Rgp1 Rhobtb3 Ric1 Sacm2l Scoc Scoco Snap Snapa Snapb Stx16 Stx6 Syb3 Sys1 Tmf1 Ttgn1 Usp6nl Vamp3 Vamp4 Vps51 Vps52 Vps53 Vps54 Vps54l Vti1a Vti1l2	Rattus norvegicus (Norway rat)
Rap1 signalling	14-3-3 protein beta/alpha 14-3-3 protein zeta/delta RAF proto-oncogene serine/threonine-protein kinase RAP1 GTPase activating protein 2 RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 (Fragment) Rap1 GTPase-activating protein Ras-related protein Rap-1A Ras-related protein Rap-1b Signal-induced proliferation-associated 1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cGMP-dependent protein kinase	A0A8I6A9E8 A0A8I6AQM4 E9PSX8 F1LV89 P0C643 P11345 P27791 P35213 P62836 P63102 P68182 Q62636 Q9R1K8 Q9Z1C7 Q9Z1C8	AABR07006724.1 Cgef2 Epac Epac1 Epac2 Krev1 Msfs1 Pkacb Prkaca Prkacb Prkg1 Raf Raf1 Rap1a Rap1b Rap1gap Rap1gap2 Rapgef3 Rapgef4 Rasgrp Rasgrp1 Rasgrp2 Sipa1 Ywhab Ywhaz	Rattus norvegicus (Norway rat)
Purine catabolism	5', 3'-nucleotidase, cytosolic 5'-nucleotidase, cytosolic IA 5'-nucleotidase, cytosolic IB 5'-nucleotidase 5-hydroxymethyl-dUMP N-hydrolase Cytosolic purine 5'-nucleotidase Guanine deaminase Inosine triphosphate pyrophosphatase Purine nucleoside phosphorylase Xanthine dehydrogenase/oxidase	A0A0G2JX78 A0A8I5ZYY7 D3ZMY7 D3ZW55 D3ZWR1 O35820 P21588 P22985 P85973 Q9WTT6	Dnph1 Gda Itpa Np Nt5 Nt5c Nt5c1a Nt5c1b Nt5c2 Nt5e Nte Pnp Rcl Xdh	Rattus norvegicus (Norway rat)
Cristae formation	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial	D3ZAF6 P05504 P10719 P11608 P15999 P19511 P21571 P29418 P29419 P31399 P35434 P35435 Q06645 Q06646 Q06647 Q5XIM4 Q6PDU7 Q71S46	Atp5a1 Atp5b Atp5c Atp5c1 Atp5d Atp5e Atp5f Atp5f1 Atp5f1a Atp5f1b Atp5f1c Atp5f1d Atp5f1e Atp5g1 Atp5g2 Atp5g3 Atp5h Atp5i Atp5j Atp5j2 Atp5jd Atp5l Atp5mc1 Atp5mc2 Atp5mc3 Atp5me Atp5mf Atp5mg Atp5o Atp5pb Atp5pd Atp5pf Atp5po Atp5s Atp6 Atp8 Atpase6 Atpase8 Dmac2l Mt-atp6 Mt-atp8 Mtatp6 Mtatp8	Rattus norvegicus (Norway rat)
The retinoid cycle in cones (daylight vision)	Acyltransferase Medium-wave-sensitive opsin 1 Retinaldehyde binding protein 1 Retinol binding protein 3 Short-wave-sensitive opsin 1	D3Z956 D4A598 G3V8Q4 O35476 Q63652	Awat2 Bcp Gcp Opn1mw Opn1sw Rbp3 Rlbp1	Rattus norvegicus (Norway rat)
Downregulation of ERBB2:ERBB3 signaling	E3 ubiquitin-protein ligase NRDP1 Polyubiquitin-B Polyubiquitin-C Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A8I6A5Y3 D3ZN39 G3V930 O35569 P06494 P0CG51 P43322 P47196 P47197 P62982 Q62799 Q63429 Q63484	Akt1 Akt2 Akt3 Erbb2 Erbb3 LOC100360645 Ndf Neu Nrg1 Nrg2 Ntak Rnf41 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Usp8	Rattus norvegicus (Norway rat)
FGFR4 ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSQ8 O54769 O88182 P13109 P36364 P61149 P63076 Q498D6 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4	Rattus norvegicus (Norway rat)
KEAP1-NFE2L2 pathway	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 Kelch-like ECH-associated protein 1 Microtubule-associated proteins 1A/1B light chain 3B Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein kinase C iota type RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase Ring-box 1 Sequestosome-1 Sestrin 1 Sestrin 2 Transitional endoplasmic reticulum ATPase UBX domain protein 7 Ubiquitin B-like Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2K4P1 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 B0BN93 B2GUV6 B5DF89 D4A1H7 D4ACF2 F1LMQ3 F1LMZ8 F1M6I7 F1M7Y5 F7FGV7 G3V6W6 G3V8G2 M0R9B9 O08623 O54968 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P46462 P47196 P47197 P48004 P57790 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q62625 Q63347 Q63429 Q63484 Q63569 Q63570 Q63797 Q63798 Q9ES53 Q9ES54 Q9JHW0 Q9WTV5 Q9Z2X3	AABR07034438.1 Akt1 Akt2 Akt3 Cul3 Inrf2 Keap1 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Map1alc3 Map1lc3 Map1lc3b Mecl1 Mss1 Mul1 Nfe2l2 Npl4 Nploc4 Nrf2 Pkcl Prkci Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Sesn1 Sesn2 Sqstm1 Sug1 Tbp1 Tbp7 Trim21 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ufd1 Ufd1l Vcp Zip	Rattus norvegicus (Norway rat)

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