GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **876 - 900** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
trans-Golgi Network Vesicle Budding	ADP-ribosylation factor 1 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Synaptosomal-associated protein 23 Syntaxin-4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	F1M8X9 O70377 P63045 P84079 Q08850 Q9JHW5 Q9WUF4	Arf1 Gbf1 Snap23 Stx4 Stx4a Syb2 Sybl1 Vamp2 Vamp7 Vamp8	Rattus norvegicus (Norway rat)
TNFR1-mediated ceramide production	Neutral sphingomyelinase activation associated factor Small ribosomal subunit protein RACK1 Sphingomyelin phosphodiesterase 2 Sphingomyelin phosphodiesterase 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor	F1M974 O35049 P16599 P22934 P63245 Q9ET64	Cca1 Gnb2l1 Nsmaf Rack1 Smpd2 Smpd3 Tnf Tnfa Tnfr-1 Tnfr1 Tnfrsf1a Tnfsf2	Rattus norvegicus (Norway rat)
HSF1 activation	14-3-3 protein epsilon Elongation factor 1-alpha 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock transcription factor 1 Prostaglandin E synthase 3 Transitional endoplasmic reticulum ATPase	F1MAF1 P34058 P46462 P62260 P62630 P82995 P83868	Eef1a Eef1a1 Hsf1 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Ptges3 Tebp Vcp Ywhae	Rattus norvegicus (Norway rat)
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin-1	F1MAL5 P01322 P0CE43 P15127 P35570	Grb10 Ins-1 Ins1 Insr Irs-1 Irs1 Irs2	Rattus norvegicus (Norway rat)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	F1MAL5 P01346 P08025 P24062 P35570	Igf-1 Igf-2 Igf1 Igf1r Igf2 Irs-1 Irs1 Irs2	Rattus norvegicus (Norway rat)
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	F1MAL5 Q07014 Q07303 Q62689	Epor Irs2 Jak2 Lyn	Rattus norvegicus (Norway rat)
MET Receptor Activation	HGF activator Hepatocyte growth factor receptor Hepatocyte growth factor Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type, 2 Serine protease hepsin	F7ELL4 G3V8S0 P17945 P97523 Q05511 Q4V8Q2	Hgf Hgfac Hpn Met Spint1 Spint2	Rattus norvegicus (Norway rat)
ATF6B (ATF6-beta) activates chaperones	Activating transcription factor 6 beta Membrane-bound transcription factor site-1 protease	F7ERH6 Q9WTZ3	Atf6b Mbtps1 S1p Ski1	Rattus norvegicus (Norway rat)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Peptidyl-prolyl cis-trans isomerase FKBP4 Prostaglandin E synthase 3 Serine/threonine-protein phosphatase 5 peptidylprolyl isomerase	F7EYK0 P06211 P34058 P53042 P82995 P83868 Q62986 Q9QVC8	Erbeta Esr Esr1 Esr2 Estr Fkbp4 Fkbp5 Fkbp52 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Nr3a1 Nr3a2 Ppp5c Ptges3 Tebp	Rattus norvegicus (Norway rat)
Regulated proteolysis of p75NTR	Disintegrin and metalloproteinase domain-containing protein 17 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Nicastrin Presenilin-1 Presenilin-2 Tumor necrosis factor receptor superfamily member 16	F7EYZ3 O88777 P07174 P97887 Q6QI68 Q8CGU6 Q9Z1K9	Adam17 Aph1a Ncstn Ngfr Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Tace Tnfrsf16	Rattus norvegicus (Norway rat)
Noncanonical activation of NOTCH3	Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 3 Nicastrin Presenilin-1 Presenilin-2 Y-box-binding protein 1	F7EYZ3 O88777 P62961 P97887 Q6QI68 Q8CGU6 Q9R172	Aph1a Ncstn Notch3 Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Yb1 Ybx1	Rattus norvegicus (Norway rat)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4E-binding protein 1 Eukaryotic translation initiation factor 4E	F7F7A6 M0RD03 P63074 Q5RKI1 Q62622	Eif4a1 Eif4a2 Eif4e Eif4ebp1 Eif4g1	Rattus norvegicus (Norway rat)
Cellular response to hypoxia	Endothelial PAS domain-containing protein 1 Hypoxia inducible factor 1 subunit alpha inhibitor Hypoxia-inducible factor 1-alpha	F7F9I0 O35800 Q9JHS1	Epas1 Hif1a Hif1an Hif2a	Rattus norvegicus (Norway rat)
Lysosomal oligosaccharide catabolism	Ab2-450 Alpha-mannosidase 2C1 Alpha-mannosidase Beta-mannosidase	F7FG85 P21139 Q4FZV0 Q7TP34	Man2b1 Man2b2 Man2c1 Manba Mrfap1	Rattus norvegicus (Norway rat)	G00027MO G25577BM G28233ME G70323CJ G90333CG
CD28 dependent Vav1 pathway	CD86 molecule Cd80 molecule Cell division control protein 42 homolog Growth factor receptor-bound protein 2 Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T-cell-specific surface glycoprotein CD28 Tyrosine-protein kinase Fyn	G3V671 O35531 P31042 P35465 P54100 P62994 Q01621 Q62829 Q62844 Q64303 Q6RUV5 Q8CFN2	Ash Cd28 Cd80 Cd86 Cdc42 Fyn Grb2 Lck Pak1 Pak2 Pak3 Rac Rac1 Vav Vav1	Rattus norvegicus (Norway rat)
AKT-mediated inactivation of FOXO1A	Forkhead box protein O1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	G3V7R4 P47196 P47197 Q63484	Akt1 Akt2 Akt3 Foxo1 Foxo1a	Rattus norvegicus (Norway rat)
GABA receptor activation	Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit alpha-2 Gamma-aminobutyric acid receptor subunit alpha-3 Gamma-aminobutyric acid receptor subunit alpha-4 Gamma-aminobutyric acid receptor subunit alpha-5 Gamma-aminobutyric acid receptor subunit alpha-6 Gamma-aminobutyric acid receptor subunit beta-1 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-3 Gamma-aminobutyric acid receptor subunit rho-1 Gamma-aminobutyric acid receptor subunit rho-2 Gamma-aminobutyric acid receptor subunit rho-3 Gamma-aminobutyric acid type A receptor subunit theta Rho guanine nucleotide exchange factor 9	G3V875 P15431 P18508 P19969 P20236 P23576 P28471 P28473 P30191 P47742 P50572 P50573 P62813 P63079 P63138 Q9QX73	Arhgef9 Gabra-1 Gabra-2 Gabra-3 Gabra-5 Gabra-6 Gabra1 Gabra2 Gabra3 Gabra4 Gabra5 Gabra6 Gabrb-1 Gabrb-2 Gabrb-3 Gabrb1 Gabrb2 Gabrb3 Gabrg2 Gabrg3 Gabrq Gabrr1 Gabrr2 Gabrr3	Rattus norvegicus (Norway rat)
Gamma-carboxylation of protein precursors	Coagulation factor IX Coagulation factor VII Coagulation factor X Osteocalcin Protein Z, vitamin K-dependent plasma glycoprotein Prothrombin Vitamin K-dependent gamma-carboxylase Vitamin K-dependent protein C Vitamin K-dependent protein S	G3V8K8 O88496 P04640 P16296 P18292 P31394 P53813 Q63207 Q8K3U6	Bglap Bglap2 Cf9 F10 F2 F7 F9 Ggcx Proc Pros Pros1 Proz	Rattus norvegicus (Norway rat)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Furin Growth arrest-specific protein 6 Osteocalcin Protein Z, vitamin K-dependent plasma glycoprotein Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S	G3V8K8 P04640 P16296 P18292 P23377 P31394 P53813 Q63207 Q63772 Q8K3U6	Bglap Bglap2 Cf9 F10 F2 F7 F9 Fur Furin Gas6 Pcsk3 Proc Pros Pros1 Proz	Rattus norvegicus (Norway rat)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest-specific protein 6 Osteocalcin Protein Z, vitamin K-dependent plasma glycoprotein Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S	G3V8K8 P04640 P16296 P18292 P31394 P53813 Q63207 Q63772 Q8K3U6	Bglap Bglap2 Cf9 F10 F2 F7 F9 Gas6 Proc Pros Pros1 Proz	Rattus norvegicus (Norway rat)
TWIK related potassium channel (TREK)	Potassium channel subfamily K member 10 Potassium channel subfamily K member 2 Potassium channel subfamily K member 4	G3V8V5 Q920B6 Q9JIS4	Kcnk10 Kcnk2 Kcnk4 Trek Trek2	Rattus norvegicus (Norway rat)
ATF6 (ATF6-alpha) activates chaperones	Cyclic AMP-dependent transcription factor ATF-6 alpha Membrane-bound transcription factor site-1 protease	G3V909 Q9WTZ3	Atf6 Mbtps1 S1p Ski1	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	Apoptosis regulator BAX Aurora kinase A Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Growth arrest and DNA damage-inducible protein GADD45 alpha Proliferating cell nuclear antigen Stratifin	G3V9A3 P04961 P30277 P39951 P48317 P59241 Q63690	Aik Airk1 Ark1 Aura Aurka Ayk1 Bax Btak Ccnb1 Cdc2 Cdc2a Cdk1 Cdkn1 Ddit1 Gadd45 Gadd45a Iak1 Pcna Sfn Stk15 Stk6	Rattus norvegicus (Norway rat)
Ubiquinol biosynthesis	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial 4-hydroxybenzoate polyprenyltransferase, mitochondrial 5-demethoxyubiquinone hydroxylase, mitochondrial (Fragment) All trans-polyprenyl-diphosphate synthase PDSS2 Atypical kinase COQ8A, mitochondrial Atypical kinase COQ8B, mitochondrial Decaprenyl diphosphate synthase subunit 1 Ubiquinone biosynthesis O-methyltransferase, mitochondrial Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial Ubiquinone biosynthesis protein COQ9, mitochondrial	M0R6Q9 Q499N4 Q4FZU1 Q4G064 Q5BJQ0 Q5U2R1 Q63159 Q63619 Q68FT1 Q68FU7 Q6AY19	Adck3 Adck4 Cabc1 Coq2 Coq3 Coq4 Coq5 Coq6 Coq7 Coq8a Coq8b Coq9 Dlp1 LOC100364990 Pdss1 Pdss2	Rattus norvegicus (Norway rat)
eNOS activation	Acyl-protein thioesterase 1 Calmodulin-3 Caveolin-1 Cytoglobin Heat shock protein HSP 90-alpha N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 Nitric oxide synthase 3 RAC-alpha serine/threonine-protein kinase Sepiapterin reductase	O08557 P0DP31 P18297 P41350 P47196 P70470 P82995 Q62600 Q921A4	Akt1 Apt1 CaMIII Calm3 Cam3 Camc Cav Cav1 Cygb Ddah Ddah1 Hsp86 Hsp90aa1 Hspca Lypla1 Nos3 Spr Stap	Rattus norvegicus (Norway rat)

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