GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
DSCAM interactions	Cell adhesion molecule DSCAM DS cell adhesion molecule-like 1	D3ZPL7 Q8VHZ8	Dscam Dscaml1	Rattus norvegicus (Norway rat)
Dopamine receptors	D(1B) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor D(4) dopamine receptor	P19020 P25115 P30729 P61169	Drd2 Drd3 Drd4 Drd5	Rattus norvegicus (Norway rat)
Multifunctional anion exchangers	Anion exchange transporter Chloride anion exchanger Pendrin Solute carrier family 26 member 11 Solute carrier family 26 member 6 Solute carrier family 26 member 9 Solute carrier family 5 member 12 Sulfate anion transporter 1 Sulfate transporter	A0A1W2Q610 D3Z9I5 D3ZV32 F1LWL8 F1M067 O70531 P45380 Q924C9 Q9R154	Dra Dtdst Pds Sat1 Slc26a1 Slc26a11 Slc26a2 Slc26a3 Slc26a4 Slc26a6 Slc26a7 Slc26a9 Slc5a12	Rattus norvegicus (Norway rat)
Synthesis of glycosylphosphatidylinositol (GPI)	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol phosphate-mannose biosynthesis regulatory protein GPI ethanolamine phosphate transferase 1 GPI ethanolamine phosphate transferase 2 GPI mannosyltransferase 1 GPI mannosyltransferase 2 Mannosyltransferase N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Phosphatidylinositol N-acetylglucosaminyltransferase subunit C Phosphatidylinositol glycan anchor biosynthesis, class F Phosphatidylinositol glycan anchor biosynthesis, class H Phosphatidylinositol glycan anchor biosynthesis, class P Phosphatidylinositol glycan anchor biosynthesis, class Q Phosphatidylinositol-glycan biosynthesis class W protein Phosphatidylinositol-glycan biosynthesis class X protein phosphatidylinositol N-acetylglucosaminyltransferase	A0A0G2K579 A0A8I5ZK79 A0A8I6A044 A0A8I6AHS9 D3ZYY8 D4AAY7 E9PTA5 M0R9J2 O35790 Q5KR61 Q5PQQ4 Q60GF7 Q642B8 Q7TSN4 Q9EQY6 Q9Z325	Dpm2 Piga Pigb Pigc Pigf Pigg Pigh Pigl Pigm Pign Pigp Pigq Pigv Pigw Pigx	Rattus norvegicus (Norway rat)
Purine catabolism	5', 3'-nucleotidase, cytosolic 5'-nucleotidase, cytosolic IA 5'-nucleotidase, cytosolic IB 5'-nucleotidase 5-hydroxymethyl-dUMP N-hydrolase Cytosolic purine 5'-nucleotidase Guanine deaminase Inosine triphosphate pyrophosphatase Purine nucleoside phosphorylase Xanthine dehydrogenase/oxidase	A0A0G2JX78 A0A8I5ZYY7 D3ZMY7 D3ZW55 D3ZWR1 O35820 P21588 P22985 P85973 Q9WTT6	Dnph1 Gda Itpa Np Nt5 Nt5c Nt5c1a Nt5c1b Nt5c2 Nt5e Nte Pnp Rcl Xdh	Rattus norvegicus (Norway rat)
Synaptic adhesion-like molecules	Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Flotillin-1 Flotillin-2 Glutamate receptor 1 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat and fibronectin type III domain-containing protein 1 Leucine-rich repeat and fibronectin type-III domain-containing protein 2 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Leucine-rich repeat and fibronectin type-III domain-containing protein 4 Receptor-type tyrosine-protein phosphatase F Receptor-type tyrosine-protein phosphatase S Reticulon-3 protein-tyrosine-phosphatase	A0A8I6A6R5 B0BNK7 D4ABX8 P0C7J6 P19490 P19492 P19493 P31016 P35439 Q00959 Q00960 Q00961 Q460M5 Q62645 Q62696 Q62936 Q64604 Q64605 Q6RJR6 Q9Z1E1 Q9Z2S9	Dlg1 Dlg3 Dlg4 Dlgh1 Dlgh3 Dlgh4 Flot1 Flot2 GluA1 GluA3 GluN2D Glur1 Glur3 Glur4 Gria1 Gria3 Gria4 Grin1 Grin2a Grin2b Grin2c Grin2d Lar Lrfn1 Lrfn2 Lrfn3 Lrfn4 Nmdar1 Psd95 Ptprd Ptprf Ptprs Reg1 Reg2 Rtn3 Salm1 Salm2 Salm3 Salm4	Rattus norvegicus (Norway rat)
PDH complex synthesizes acetyl-CoA from PYR	Ac1164 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	D4A5G8 P08461 P26284 P49432 Q06437 Q6P6R2 Q7TQ85	Dlat Dld LOC311254 Pdha1 Pdha1l1 Pdha2 Pdhb Pdhx	Rattus norvegicus (Norway rat)
Regulation of pyruvate dehydrogenase (PDH) complex	Ac1164 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Maleylacetoacetate isomerase NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase phosphatase regulatory subunit [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial	A0A0G2K6D8 A0A8I5ZQQ3 D4A5G8 O54937 O88483 O88484 P08461 P26284 P49432 P57113 Q06437 Q63065 Q64536 Q6P6R2 Q7TQ85	Dlat Dld Gstz1 LOC311254 Pdh Pdha1 Pdha1l1 Pdha2 Pdhb Pdhx Pdk1 Pdk2 Pdk4 Pdp1 Pdp2 Pdpr Ppm2c SIRT4 Sirt4	Rattus norvegicus (Norway rat)
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	Dickkopf WNT signaling pathway inhibitor 2 Dickkopf WNT signaling pathway inhibitor 4 Kremen protein 1 Kremen protein Low-density lipoprotein receptor-related protein Low-density lipoprotein receptor-related protein Sclerostin	A0A0G2K0H3 A0A8I6G721 D3ZN48 D4ADQ6 D4ADS5 Q924S4 Q99P67	Dkk2 Dkk4 Kremen Kremen1 Kremen2 Lrp5 Lrp6 Sost	Rattus norvegicus (Norway rat)
Release of Hh-Np from the secreting cell	Dispatched RND transporter family member 2 Glypican 5 Hedgehog protein Hedgehog protein Signal peptide, CUB domain and EGF like domain containing 2 Sonic hedgehog protein [Wnt protein] O-palmitoleoyl-L-serine hydrolase	A0A8I6ACQ6 D3ZBZ6 D3ZXI3 D4AC02 F1LP42 G3V7Y0 Q63673	Dhh Disp2 Gpc5 Ihh Notum Scube2 Shh Vhh-1	Rattus norvegicus (Norway rat)
Hedgehog ligand biogenesis	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Derlin Endoplasmic reticulum lectin Hedgehog acyltransferase Hedgehog protein Hedgehog protein Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein OS-9 Protein disulfide-isomerase Protein sel-1 homolog 1 RING-type E3 ubiquitin transferase Sonic hedgehog protein Transitional endoplasmic reticulum ATPase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6AMH0 A0A8I6GIY5 B0BN93 D3ZF97 F1LMQ3 F1LMZ8 F1LP42 F1M6I7 F7FG68 F7FGV7 G3V6W6 G3V7Y0 G3V8G2 O88761 P04785 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P46462 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5RKH6 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63673 Q63797 Q63798 Q80Z70 Q9JHW0 Q9WTV5 Q9Z2X3	Derl2 Dhh Erlec1 Hhat Ihh LOC100360645 LOC100360846 LOC100365869 LOC100910831 Lmp10 Lmp2 Mecl1 Mss1 Os9 P4hb Pdia1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ring12 Rps27a Sel1h Sel1l Shh Sug1 Syvn1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vcp Vhh-1	Rattus norvegicus (Norway rat)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A8I6A8V2 A0A8I6G4T5 A0A8I6GEB4 D4A7L6 F7FLB2 P05370 P50137 P85968 P85971 Q9EQS0	Dera G6pd G6pdx Pgd Pgls Pgm2 RBKS Rbks Rpe Rpia Taldo1 Tkt	Rattus norvegicus (Norway rat)	G31080DL
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Protein DEK Transcription factor AP-2-alpha	P58197 Q6AXS3	Dek Tcfap2a Tfap2a	Rattus norvegicus (Norway rat)
Defensins	Alpha-defensin N-terminal domain-containing protein Beta-defensin 14 Beta-defensin 17 Beta-defensin 18 Beta-defensin 1 Beta-defensin 25 Beta-defensin 30 Beta-defensin 41 Beta-defensin 43 Beta-defensin 4 Beta-defensin Beta-defensin Beta-defensin Beta-defensin Defensin alpha 10 Defensin alpha 11 Defensin alpha 24 Defensin alpha 4 Defensin alpha 6 Defensin alpha 8 Defensin alpha 9 Defensin alpha-like protein 1 Neutrophil antibiotic peptide NP-2 Neutrophil antibiotic peptide NP-3B	A0A8I6GLV0 A0A8J8YAJ6 F1LSU5 F7EMF7 F7FD31 O88514 O89117 Q32ZF3 Q32ZF5 Q32ZG2 Q32ZG7 Q32ZH1 Q32ZH4 Q32ZH5 Q32ZH7 Q4JEI2 Q4JEI3 Q4JEI5 Q4JEI6 Q4JEI8 Q4JEI9 Q62714 Q62715 Q9Z1F1	Defa Defa-rs1 Defa10 Defa11 Defa24 Defa6 Defa8 Defa9 Defal1 Defb1 Defb14 Defb17 Defb18 Defb2 Defb21 Defb24 Defb25 Defb28 Defb3 Defb30 Defb36 Defb4 Defb41 Defb43 Defcr4 ENSRNOG00000064390 Np4 Rd5	Rattus norvegicus (Norway rat)
Deadenylation of mRNA	Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4E PAN2-PAN3 deadenylation complex catalytic subunit Pan2 PAN2-PAN3 deadenylation complex subunit PAN3 Poly(A) binding protein interacting protein 1 Polyadenylate-binding protein 1	A0A0G2JVP5 D4ADM2 F7F7A6 M0RD03 P63074 Q3B8Q2 Q5RKI1 Q6IE70 Q9EPH8	Ddx48 Eif4a1 Eif4a2 Eif4a3 Eif4e Eif4g1 PAN3 Pabp1 Pabpc1 Paip1 Pan2 Pan3 Usp52	Rattus norvegicus (Norway rat)
Non-integrin membrane-ECM interactions	Epithelial discoidin domain-containing receptor 1 receptor protein-tyrosine kinase	B1WC09 Q63474	Ddr1 Ddr2 Eddr1 Ptk3	Rattus norvegicus (Norway rat)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase 5'-3' exoribonuclease 1 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease Exosome complex component RRP45 Exosome component 1 Exosome component 2 Exosome component 4 Exosome component 5 Exosome component 6 M7GpppN-mRNA hydrolase-like MAPK activated protein kinase 2 Ribosomal RNA-processing protein 40 Ribosomal RNA-processing protein 42 Ribosomal RNA-processing protein 43 Transportin 1 mRNA decay activator protein ZFP36	A0A0G2QC37 A0A8I5ZNY7 A0A8I6GHQ8 D3ZBP3 D3ZT51 D3ZW38 D4A4Y0 D4ABN8 D4AE80 D4AE98 F1LQP9 F7EPZ4 M0RDC9 P35213 P47973 Q4QR75 Q80ZF4	Dcp1a Dcp2 Dis3 Exosc1 Exosc2 Exosc3 Exosc4 Exosc5 Exosc6 Exosc7 Exosc8 Exosc9 LOC103690064 LOC679140 Mapkapk2 Tis11 Tnpo1 Ttp Xrn1 Ywhab Zfp36	Rattus norvegicus (Norway rat)
Netrin-1 signaling	Ezrin Netrin 4 Netrin receptor DCC Netrin receptor UNC5A Protein kinase C theta type	F1M4Q9 O08721 P31977 Q63155 Q9WTQ0	Dcc Ezr Ntn4 Pkcq Prkcq Unc5a Unc5h1 Vil2	Rattus norvegicus (Norway rat)
Protein lipoylation	Acyl carrier protein Adrenodoxin, mitochondrial Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Lipoyl synthase, mitochondrial Lipoyltransferase 1 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial Octanoyl-[acyl-carrier-protein]	A0A8I5ZRJ8 B2GV15 D3Z9Z2 D3ZA85 D3ZF13 P08461 P24483 Q01205 Q5I0P2 Q5XIH4	Dbt Dlat Dlst Fdx1 Gcsh Lias Lipt1 Lipt2 Ndufab1 Nfu1	Rattus norvegicus (Norway rat)
Catecholamine biosynthesis	Aromatic-L-amino-acid decarboxylase Dopamine beta-hydroxylase Phenylethanolamine N-methyltransferase Tyrosine 3-monooxygenase	P04177 P10937 P14173 Q05754	Dbh Ddc Pnmt Th	Rattus norvegicus (Norway rat)
Elastic fibre formation	Elastin Fibrillin 1 Fibulin-5 Furin Integrin beta-1 Integrin beta-3 Integrin beta-6 Integrin subunit alpha 5 Integrin subunit alpha V Lysyl oxidase homolog 2 Lysyl oxidase homolog Microfibril associated protein 2 Microfibril associated protein 5 Protein-lysine 6-oxidase protein-lysine 6-oxidase protein-lysine 6-oxidase	A0A0G2K1E2 A0A0G2K9S8 B5DF27 D3Z952 D3ZP82 D4A9V5 F1LZX9 G3V9M6 P16636 P23377 P49134 Q5FWS5 Q6AYF4 Q8R2H2 Q99372 Q9WVH8	Dance Eln Fbln5 Fbn1 Fur Furin Itga5 Itgav Itgb1 Itgb3 Itgb6 Lox Loxl1 Loxl2 Loxl3 Loxl4 Mfap2 Mfap5 Pcsk3	Rattus norvegicus (Norway rat)
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase beta Diacylglycerol kinase gamma Diacylglycerol kinase iota Diacylglycerol kinase theta Diacylglycerol kinase zeta Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C theta type Short transient receptor potential channel 3 Transient receptor potential cation channel, subfamily C, member 7	A0A096UWG9 D3ZEY4 D3ZSZ6 F1LQF7 F1LZW2 F1M5T2 F1MAB7 O08560 P09215 P09216 P29994 P29995 P49620 P49621 P51556 Q63269 Q64617 Q9JMI9 Q9WTQ0	Dagk Dagk1 Dagk2 Dagk3 Dagk6 Dgka Dgkb Dgkd Dgke Dgkg Dgkh Dgki Dgkk Dgkq Dgkz Insp3r Itpr1 Itpr2 Itpr3 Pkcd Pkce Pkch Pkcq Prkcd Prkce Prkch Prkcq Trpc3 Trpc7 Trrp3	Rattus norvegicus (Norway rat)
Reelin signalling pathway	Disabled homolog 1 Reelin SH3 domain-containing kinase-binding protein 1 Tyrosine-protein kinase Fyn Very low-density lipoprotein receptor	P58751 P98166 Q62844 Q8CJH2 Q925Q9	Dab1 Fyn Reln Ruk Seta Sh3kbp1 Vldlr	Rattus norvegicus (Norway rat)
The canonical retinoid cycle in rods (twilight vision)	Cytochrome P450 4V2 LRRGT00111 Lecithin retinol acyltransferase Myosin VIIA Receptor for retinol uptake STRA6 Retinaldehyde binding protein 1 Retinoid isomerohydrolase Retinol binding protein 3 Retinol dehydrogenase 10 Retinol dehydrogenase 12 Retinol-binding protein 1 Retinol-binding protein 4 Rhodopsin Transthyretin	A0A8I5ZWB0 A2RRT9 D3Z956 D3ZEP9 G3V8Q4 O70276 P02696 P02767 P04916 P51489 Q4QR83 Q6TUD3 Q80ZF7 Q9JI61	Cyp4v2 Cyp4v3 Lrat Myo7a Rbp-1 Rbp1 Rbp3 Rbp4 Rdh10 Rdh11 Rdh12 Rho Rlbp1 Rpe65 Stra6 Tt Ttr	Rattus norvegicus (Norway rat)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	Cytochrome P450 1A2	P04799	Cyp1a-2 Cyp1a2	Rattus norvegicus (Norway rat)

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