GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-mannosidase 2 Alpha-mannosidase Carbohydrate sulfotransferase 10 Tissue alpha-L-fucosidase	A0A0G2JWG1 O54702 P17164 P28494 Q09326 Q6EV76	Chst10 Fuca Fuca1 Fut8 Gnt2 Man2a1 Man2a2 Mana2 Mgat2	Rattus norvegicus (Norway rat)	G70323CJ G82576YO
Condensation of Prometaphase Chromosomes	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Condensin complex subunit 1 Condensin complex subunit 2 Non-SMC condensin I complex, subunit G Structural maintenance of chromosomes protein Structural maintenance of chromosomes protein	A0A0G2JWH3 A0A8I6GK63 D3ZD72 D4A5Q2 D4A8M7 F7FH41 P19139 P67874	Ck2n Csnk2a1 Csnk2a2 Csnk2b Ncapd2 Ncapg Ncaph Smc2 Smc4	Rattus norvegicus (Norway rat)
PKR-mediated signaling	Alpha-synuclein Cellular tumor antigen p53 Cyclin-dependent kinase 1 Cytoplasmic protein DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase FA complementation group A FA complementation group B FA complementation group E FA complementation group F FA complementation group G FA complementation group L FA complementation group M FA core complex associated protein 100 FA core complex associated protein 24 Fanconi anemia core complex-associated protein 20 Fanconi anemia group C protein homolog Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 ISG15 ubiquitin-like modifier Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Microtubule-associated protein tau Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleophosmin Protein phosphatase 2 scaffold subunit A alpha RBR-type E3 ubiquitin transferase RISC-loading complex subunit TARBP2 RNA helicase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Sphingosine kinase 1 Tripartite motif-containing 25 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin/ISG15-conjugating enzyme E2 L6 mitogen-activated protein kinase kinase	A0A0G2JWL4 A0A0G2JX93 A0A0G2K7F0 A0A8I5ZNL4 A0A8I6ABZ7 A0A8I6AGX8 A0A8I6AH74 A0A8I6ANR6 B2RZ33 D3ZAU3 D3ZDI7 D3ZE71 D3ZXL1 D4A3X3 D4A5I2 D4A9N5 D4AAA5 F1M0R6 F1M286 O35870 P0DMW0 P0DMW1 P10361 P13084 P14659 P19332 P35233 P37377 P39951 P52631 P55063 P55266 P62716 P63018 P63331 Q3SWU0 Q4QQT4 Q4V8C7 Q4V8J2 Q5XI34 Q63184 Q66HG9 Q6TMG5 Q7TP98 Q91V26 Q925D6 Q9JIL3 Q9QY78 Q9R0T3	Adar Arih1 Cdc2 Cdc2a Cdk1 Cdkn1 Chuk Dhx9 Dnajc3 Dsrad Eif2ak2 Faap100 Faap20 Faap24 Facc Fanca Fancb Fancc Fance Fancf Fancg Fancl Fancm Hsc70 Hsc73 Hsp70-1 Hsp70-2 Hsp70-3 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hst70 Ikbkb Ikbkg Ikkb Ilf2 Ilf3 Ips1 Isg15 Map2k6 Mapt Mavs Mkk6 Mtapt Nck1 Nemo Npm1 P53 P58ipk Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Prkr Prkra Ptpn2 RGD1564719 Snca Sphk1 Stat1 Stat3 Stat4 Tarbp2 Tau Tp53 Trim25 Ube2l6 Visa	Rattus norvegicus (Norway rat)
Interleukin-20 family signaling	Interferon, lambda 1 Interferon, lambda 3 Interferon, lambda receptor 1 Interleukin 10 receptor subunit beta Interleukin 20 receptor subunit alpha Interleukin 20 receptor subunit beta Interleukin 22 receptor subunit alpha 1 Interleukin 22 Interleukin family protein Interleukin family protein Interleukin-22 receptor subunit alpha-2 Interleukin-24 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A0G2JWM7 A0A0G2JX93 A0A8I5ZW17 A0A8I6A0L8 A0A8I6AM23 D3ZB58 D3ZD03 D3ZFI7 D3ZJZ2 D3ZM36 D4A2T8 F1M3K4 F7EYG9 G3V6X6 P41499 P52631 P52632 Q62689 Q62771 Q63272 Q7TNI4 Q9JI24	If2d Ifnl1 Ifnl3 Ifnlr1 Il10rb Il19 Il20 Il20ra Il20rb Il22 Il22ra1 Il22ra2 Il24 Il28b Il28ra Jak1 Jak2 Jak3 Mgf Mob5 Ptpn11 Stat1 Stat2 Stat3 Stat4 Stat5a Stat5b Tyk2	Rattus norvegicus (Norway rat)
RNA Polymerase I Promoter Escape	CDK-activating kinase assembly factor MAT1 Chromobox 3 Cyclin-H Cyclin-dependent kinase 7 (Fragment) DNA-directed RNA polymerase I subunit RPA12 DNA-directed RNA polymerase I subunit RPA1 DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Nucleolar transcription factor 1 RNA polymerase I subunit E RNA polymerase I subunit G RRN3 homolog, RNA polymerase I transcription factor TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit D TATA box-binding protein-associated factor, RNA polymerase I, subunit C TATA-box-binding protein	A0A0G2JWQ0 A0A0G2JXI9 A0A0G2K8U0 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6A9T0 A0A8I6AFW8 A0A8I6AH26 A0A8I6AWT3 A0A8I6AXL7 A0A8I6G659 A0JN27 A9UMV8 B0BN64 B0BNE2 D3ZEI7 D3ZJ08 D3ZVK7 D3ZXP3 D3ZYB7 D4ACM0 D4ADE7 D4ADH7 F7EX11 G3V9C7 M0RBH0 M0RBQ5 O54888 O54889 O88828 P0CC09 P25977 P51952 P62804 P84245 Q00729 Q3B7U2 Q4G005 Q561R7 Q5M948 Q5RJK5 Q6LED0 Q6MFY5 Q6P773 Q9R1A0	AC109542.1 Cak Cak1 Cbx3 Ccnh Cd3eap Cdk7 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Ercc2 Ercc3 Gtf2h1 Gtf2h2 Gtf2h3 Gtf2h5 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Josd3 LOC100360260 LOC100360453 LOC100365043 LOC100910200 LOC120097726 LOC120098305 LOC684797 Mnat1 Mo15 Polr1a Polr1b Polr1e Polr1f Polr1g Polr1h Polr2e Polr2f Rpa1 Rpa2 Rpo1-2 Rpo1-4 Rrn3 Taf1a Taf1b Taf1c Taf1d Tbp Tcfubf Th2b Twistnb Ubf-1 Ubtf Znrd1	Rattus norvegicus (Norway rat)
Ion transport by P-type ATPases	ATPase 13A1 ATPase cation transporting 13A2 Calcium-transporting ATPase type 2C member 1 Calcium-transporting ATPase type 2C member 2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-3 Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase Copper-transporting ATPase 1 Copper-transporting ATPase 2 FXYD domain-containing ion transport regulator 3 FXYD domain-containing ion transport regulator 4 FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 PDZ domain-containing protein 11 Phospholemman Phospholipid-transporting ATPase IC Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Potassium-transporting ATPase alpha chain 1 Potassium-transporting ATPase alpha chain 2 Potassium-transporting ATPase subunit beta Probable phospholipid-transporting ATPase IIB Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit alpha-4 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit gamma Sorcin	A0A0G2JWQ8 A0A1B0GWR9 A0A8I5Y9D1 A0A8I5Y9M9 A0A8I5ZVG5 A0A8I5ZXX6 A0A8I6A3Z6 A0A8I6A6I4 A0A8I6A9Z8 A0A8I6GI47 D3ZE62 D3ZN41 D4A4W5 D4A7K5 D4AA47 D4ABB8 F1M9L4 F1MA70 F1MAA4 G3V7I3 O08589 P06685 P06686 P06687 P07340 P08413 P09626 P0DP31 P11275 P11505 P11507 P11730 P13638 P15791 P18596 P18598 P54708 P59645 P59649 P61016 P70705 Q04679 Q63113 Q63377 Q64535 Q64541 Q64542 Q64566 Q64568 Q64578 Q8R4C1 Q91XV6	Atp10a Atp10b Atp10d Atp11a Atp11b Atp11c Atp12a Atp13a1 Atp13a2 Atp13a4 Atp13a5 Atp1a1 Atp1a2 Atp1a3 Atp1a4 Atp1al1 Atp1al2 Atp1b1 Atp1b2 Atp1b3 Atp1c Atp1g1 Atp2a1 Atp2a2 Atp2a3 Atp2b1 Atp2b3 Atp2b4 Atp2c1 Atp2c2 Atp4a Atp4b Atp7a Atp7b Atp8a1 Atp8a2 Atp8b1 Atp8b2 Atp8b3 Atp8b4 Atp9a Atp9b CaMIII Calm3 Cam3 Camc Camk2a Camk2b Camk2d Camk2g Fxyd1 Fxyd2 Fxyd3 Fxyd4 Fxyd6 Fxyd7 Hka Mnk Pdzd11 Php Pina Plm Pln Pmca3 Spca2 Sri Wnd	Rattus norvegicus (Norway rat)
Class I peroxisomal membrane protein import	ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 Acyl-CoA-binding domain-containing protein 5 Aldehyde dehydrogenase family 3 member A2 Ganglioside-induced differentiation-associated-protein 1 Mitochondrial fission 1 protein Outer mitochondrial transmembrane helix translocase Peroxisomal biogenesis factor 11 beta Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Peroxisomal membrane protein 2 Peroxisomal membrane protein 4 Peroxisomal membrane protein PEX14 Peroxisomal membrane protein PEX16 Peroxisome assembly protein 12 Peroxisome biogenesis factor 2	A0A0G2JWT6 A0FKI7 D3ZHR2 D4A5X7 F7FA09 O88177 P16970 P24392 P30839 P59382 P84817 Q07066 Q505J9 Q642G4 Q9JJK4 Q9QY44 Q9QYU1	Abcd1 Abcd2 Abcd3 Acbd5 Aldh3a2 Aldh4 Aldr Aldrp Atad1 Fis1 Gdap1 Npg6 Paf1 Paf3 Pex11b Pex12 Pex14 Pex16 Pex19 Pex2 Pex3 Pmp22 Pmp24 Pmp35 Pmp70 Pxf Pxmp1 Pxmp2 Pxmp3 Pxmp4 Ttc11	Rattus norvegicus (Norway rat)
Cleavage of the damaged purine	Adenine DNA glycosylase Adrenocortical dysplasia protein homolog DNA-(apurinic or apyrimidinic site) lyase DNA-3-methyladenine glycosylase (Fragment) Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor	A0A0G2JX31 A0A0G2JXI9 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A9UMV8 D3ZJF7 D3ZKJ8 D3ZVK7 D3ZXP3 D4ACM0 G3V9C7 M0RBQ5 O70249 P0CC09 P23571 P62804 Q00729 Q4FZR5 Q5EAN7 Q8R5G2	Acd ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist4 Hist4h4 LOC100365043 LOC100910200 LOC120097726 LOC684797 Mmh Mpg Mutyh Myh Neil3 Ogg1 Ogh1 Pot1 Rap1 Terf2 Terf2ip Th2b	Rattus norvegicus (Norway rat)
Recognition and association of DNA glycosylase with site containing an affected purine	Adrenocortical dysplasia protein homolog DNA-(apurinic or apyrimidinic site) lyase Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor	A0A0G2JX31 A0A0G2JXI9 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A9UMV8 D3ZJF7 D3ZKJ8 D3ZVK7 D3ZXP3 D4ACM0 G3V9C7 M0RBQ5 O70249 P0CC09 P62804 Q00729 Q4FZR5 Q5EAN7	Acd ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist4 Hist4h4 LOC100365043 LOC100910200 LOC120097726 LOC684797 Mmh Neil3 Ogg1 Ogh1 Pot1 Rap1 Terf2 Terf2ip Th2b	Rattus norvegicus (Norway rat)
Phosphate bond hydrolysis by NTPDase proteins	Ectonucleoside triphosphate diphosphohydrolase 1 Ectonucleoside triphosphate diphosphohydrolase 2 Ectonucleoside triphosphate diphosphohydrolase 3 Ectonucleoside triphosphate diphosphohydrolase 4 Ectonucleoside triphosphate diphosphohydrolase 5 Ectonucleoside triphosphate diphosphohydrolase 6 Ectonucleoside triphosphate diphosphohydrolase 7 Ectonucleoside triphosphate diphosphohydrolase 8	A0A0G2JX61 A0A0G2K5S7 A0A8J8YF16 O35795 P97687 Q5DRK1 Q6P6S9 Q9ER31	Cd39 Cd39l1 Cd39l2 Entpd1 Entpd2 Entpd3 Entpd4 Entpd5 Entpd6 Entpd7 Entpd8	Rattus norvegicus (Norway rat)
Purine catabolism	5', 3'-nucleotidase, cytosolic 5'-nucleotidase, cytosolic IA 5'-nucleotidase, cytosolic IB 5'-nucleotidase 5-hydroxymethyl-dUMP N-hydrolase Cytosolic purine 5'-nucleotidase Guanine deaminase Inosine triphosphate pyrophosphatase Purine nucleoside phosphorylase Xanthine dehydrogenase/oxidase	A0A0G2JX78 A0A8I5ZYY7 D3ZMY7 D3ZW55 D3ZWR1 O35820 P21588 P22985 P85973 Q9WTT6	Dnph1 Gda Itpa Np Nt5 Nt5c Nt5c1a Nt5c1b Nt5c2 Nt5e Nte Pnp Rcl Xdh	Rattus norvegicus (Norway rat)
ISG15 antiviral mechanism	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beclin-1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase NEDD4 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4 gamma 2 Eukaryotic translation initiation factor 4 gamma, 3 Eukaryotic translation initiation factor 4E Filamin B ISG15 ubiquitin-like modifier Interferon regulatory factor 3 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1B-like Interferon-induced, double-stranded RNA-activated protein kinase Mitogen-activated protein kinase 3 Protein phosphatase 1B RBR-type E3 ubiquitin transferase RNA helicase Signal transducer and activator of transcription 4 Tripartite motif-containing 25 Tyrosine-protein kinase Ubiquitin-like modifier activating enzyme 7 Ubiquitin/ISG15-conjugating enzyme E2 L6 ubiquitinyl hydrolase 1	A0A0G2JX93 A0A0G2JXT8 A0A0G2K735 A0A8I6A1T4 A0A8I6AM23 A0A8I6AMY8 A0A8I6APR1 D3ZXL1 D4A3X3 D4A9N5 D4ADT5 F1M3L4 F7EXX5 F7F7A6 M0RD03 P10686 P18589 P21708 P35815 P63074 Q3B8Q2 Q4V8J2 Q5RKI1 Q62940 Q63184 Q6AYC7 Q91XJ1	Arih1 Becn1 Ddx48 Eif2ak2 Eif4a1 Eif4a2 Eif4a3 Eif4e Eif4g1 Eif4g2 Eif4g3 Erk1 Flnb Ifit1bl Irf3 Isg15 Jak1 LOC100366017 Mapk3 Mx2 Nedd4 Nedd4a Plcg1 Pp2c2 Ppm1b Pppm1b Prkm3 Prkr Rig1 Rpf1 Stat1 Stat4 Trim25 Uba7 Ube2e1 Ube2l6 Usp18	Rattus norvegicus (Norway rat)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B (Fragment) Proto-oncogene tyrosine-protein kinase Src Rap guanine nucleotide exchange factor 1 Ras GTPase-activating protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription Tyrosine-protein phosphatase non-receptor type 11	A0A0G2JX93 A0A0G2K2M3 A0A0G2K344 B2RZ33 D4A3M8 D4A3T0 F1M8L9 P08644 P10686 P20171 P20786 P28576 P41499 P50904 P52631 P52632 P62994 Q04970 Q05028 Q05030 Q5U2U2 Q62771 Q63767 Q63768 Q63787 Q63788 Q9QZC5 Q9WUD9 Q9Z1L0	Ash Bcar1 Cas Crk Crkas Crkl Crko Grb2 Grb7 Hras Hras1 Kras Kras2 Mgf Nck1 Nck2 Nras Pdgfa Pdgfb Pdgfr Pdgfr1 Pdgfra Pdgfrb Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg1 Ptpn11 Rapgef1 Rasa Rasa1 Rpa1 Sos1 Src Stat1 Stat3 Stat4 Stat5a Stat5b Stat6	Rattus norvegicus (Norway rat)
Interleukin-4 and Interleukin-13 signaling	Endoplasmin Interleukin 13 receptor subunit alpha 1 Interleukin-13 receptor subunit alpha-2 Interleukin-13 Interleukin-4 receptor subunit alpha Interleukin-4 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase Tyrosine-protein kinase	A0A0G2JX93 A0A0G2K2M3 A0A8I6AM23 D3ZD03 D3ZUE4 P20096 P42203 P52631 Q561K3 Q62689 Q63257 Q63272 Q66HD0 Q8VHK6 Q9QX78	Grp94 Hsp90b1 Hspc4 Il-13 Il-4 Il13 Il13ra1 Il13ra1-ps1 Il13ra2 Il4 Il4r Il4ra Jak1 Jak2 Jak3 LOC100360218 Socs1 Socs5 Stat1 Stat3 Stat4 Stat6 Tra1 Tyk2	Rattus norvegicus (Norway rat)
Signaling by SCF-KIT	Chymase GRB2-associated-binding protein 2 GRB2-related adaptor protein 2 GRB2-related adaptor protein GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Kit ligand Mast/stem cell growth factor receptor Matrix metalloproteinase-9 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Serine/threonine-protein kinase Chk1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase Fer Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 protein-tyrosine-phosphatase	A0A0G2JX93 A0A0G2K344 A0A0G2K3H0 A0A8I6A3K6 D4A3T0 D4A584 F1LM93 P05696 P08644 P09760 P0CE43 P20171 P21581 P41499 P50282 P50339 P52631 P52632 P54100 P62994 Q01621 Q04970 Q07014 Q3KR57 Q4KM68 Q62689 Q62771 Q62844 Q63116 Q63787 Q63788 Q63789 Q6RUV5 Q91ZN7 Q9EQH1 Q9QZC5 Q9WUD9	Ash Chek1 Chk1 Cma1 Fer Fert2 Fes Flk Fyn Gab2 Grap Grap2 Grb10 Grb2 Grb7 Hras Hras1 Jak2 KIT Kit Kitl Kitlg Kras Kras2 Lck Lyn Mcpt3 Mgf Mmp9 Nras Pik3ca Pik3r1 Pik3r2 Pik3r3 Pkca Prkca Ptpn11 Ptpru Rac Rac1 Sos1 Src Stat1 Stat3 Stat4 Stat5a Stat5b Tec Vav Vav1 Yes1	Rattus norvegicus (Norway rat)
Interferon alpha/beta signaling	ATP binding cassette subfamily E member 1 Importin subunit alpha-5 Importin subunit beta-1 Interferon 1ai1 Interferon 1ai2 Interferon 1ai3 Interferon alpha and beta receptor subunit 1 Interferon alpha and beta receptor subunit 2 Interferon alpha-1-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-1 Interferon beta Interferon regulatory factor 9 Polyubiquitin-B Polyubiquitin-C Ribonuclease L Signal transducer and activator of transcription 4 Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	A0A0G2JX93 A0A7R8C3L7 A0A8I5ZN08 A0A8I5ZQE9 A0A8I5ZQR5 A0A8I6A4N8 A0A8I6A5Y3 A0A8I6AEQ7 A0A8I6AM23 A0A8I6AN84 A0A8I6ANZ6 A0A8I6GMD9 D3Z919 D3ZD03 D3ZD23 D3ZDS9 D3ZFH0 F7EYG9 G3V915 M0R8H7 O88583 P05011 P0CG51 P52296 P62982 P70499 P83953 Q63429 Q9QX78	Abce1 Cish3 ENSRNOG00000065554 If1ai1 If1ai2 If1ai3 Ifna1 Ifna12l Ifna4 Ifna4l1 Ifnar1 Ifnar2 Ifnb Ifnb1 Irf9 Jak1 Kpna1 Kpnb1 LOC100360645 LOC100911527 LOC120103158 LOC120103159 LOC120103160 LOC120103161 LOC120103162 LOC120103163 LOC120103164 RGD1560539 Rnasel Rps27a Socs1 Socs3 Stat1 Stat2 Stat4 Tyk2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Regulation of IFNA/IFNB signaling	Interferon 1ai1 Interferon 1ai2 Interferon 1ai3 Interferon alpha and beta receptor subunit 1 Interferon alpha and beta receptor subunit 2 Interferon alpha-1-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-1 Interferon beta Signal transducer and activator of transcription 4 Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Uncharacterized protein ubiquitinyl hydrolase 1	A0A0G2JX93 A0A7R8C3L7 A0A8I5ZN08 A0A8I5ZQR5 A0A8I6A4N8 A0A8I6AEQ7 A0A8I6AM23 A0A8I6AN84 A0A8I6ANZ6 A0A8I6GMD9 D3Z919 D3ZD03 D3ZDS9 D3ZFH0 F7EYG9 M0R8H7 P05011 P20417 P41499 P70499 P81718 Q6AYC7	ENSRNOG00000065554 If1ai1 If1ai2 If1ai3 Ifna1 Ifna12l Ifna4 Ifna4l1 Ifnar1 Ifnar2 Ifnb Ifnb1 Jak1 LOC100911527 LOC120103158 LOC120103159 LOC120103160 LOC120103161 LOC120103162 LOC120103163 LOC120103164 Ptph6 Ptpn1 Ptpn11 Ptpn6 RGD1560539 Stat1 Stat2 Stat4 Tyk2 Usp18	Rattus norvegicus (Norway rat)
Interleukin-21 signaling	Interleukin 21 receptor Interleukin-21 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase	A0A0G2JX93 A0A8I5ZRF2 A0A8I6AM23 A3QPB9 P52631 P52632 Q62771 Q63272	Il21 Il21r Jak1 Jak3 Mgf Stat1 Stat3 Stat4 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Interleukin-9 signaling	Interleukin 9 receptor Interleukin 9 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AHK3 A0A8I6AM23 D4A8I9 P52631 P52632 Q62771 Q63272	Il9 Il9r Jak1 Jak3 Mgf Stat1 Stat3 Stat4 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Regulation of IFNG signaling	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Protein inhibitor of activated STAT, 1 Signal transducer and activator of transcription 4 Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 2	A0A0G2JX93 A0A8I6AJT7 A0A8I6AM23 D4A109 F7FHZ1 O88583 P01581 P35233 Q5I0H3 Q62689 Q9QX78	Cish3 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Pias1 Ptpn2 Socs1 Socs3 Stat1 Stat4 Sumo1	Rattus norvegicus (Norway rat)
Interleukin-6 signaling	E3 ubiquitin-protein ligase CBL Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A0G2JX93 A0A8I6AM23 A0A8I6G3R2 D3ZD03 O88583 P20607 P22273 P40190 P41499 P52631 Q62689	Cbl Cish3 Il-6 Il6 Il6r Il6ra Il6st Jak1 Jak2 Ptpn11 Socs3 Stat1 Stat3 Stat4 Tyk2	Rattus norvegicus (Norway rat)
Interleukin-27 signaling	Calnexin Cytokine receptor-like factor 1 Epstein-Barr virus induced 3 Interleukin 27 Interleukin-6 receptor subunit beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AM23 D3ZD03 D3ZIV9 D3ZPW3 M0RD76 P35565 P40190 P52631 Q62689	Canx Crlf1 Ebi3 Il27 Il6st Jak1 Jak2 Stat1 Stat3 Stat4 Tyk2	Rattus norvegicus (Norway rat)
Interleukin-35 Signalling	Calnexin Epstein-Barr virus induced 3 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-6 receptor subunit beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AM23 D3ZD03 F1LRH7 M0RD76 P35565 P40190 P52631 Q62689 Q9R103	Canx Ebi3 Il12a Il12rb2 Il6st Jak1 Jak2 Stat1 Stat3 Stat4 Tyk2	Rattus norvegicus (Norway rat)
Interferon gamma signaling	Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Protein kinase C delta type Signal transducer and activator of transcription 4 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 6 Y-box-binding protein 1	A0A0G2JX93 A0A8I6AM23 D4A109 F7FHZ1 O88583 P01581 P08413 P09215 P11275 P11730 P15791 P21708 P62961 P63086 P81718 Q62689 Q9QX78	Camk2a Camk2b Camk2d Camk2g Cish3 Erk1 Erk2 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Mapk Mapk1 Mapk3 Pkcd Prkcd Prkm1 Prkm3 Ptph6 Ptpn6 Socs1 Socs3 Stat1 Stat4 Yb1 Ybx1	Rattus norvegicus (Norway rat)
Regulation of CDH11 function	ADAM metallopeptidase domain 19 ADAM metallopeptidase domain 33 Angiomotin Angiopoietin-related protein 4 Cadherin 11 Catenin beta-1 Catenin delta 1 Junction plakoglobin	A0A0G2JX94 A0A0G2JXM1 A0A8I5ZUZ5 D3ZPM7 F1MAH6 Q6P0K8 Q6TMA8 Q9WU82	Adam19 Adam33 Amot Angptl4 Catnb Cdh11 Ctnnb1 Ctnnd1 Jup Pg	Rattus norvegicus (Norway rat)

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