alcohol dependence

Summary
Synonym
  • alcoholism
Definition
A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.
Super Class
substance dependence
External Links
Disease Ontology
DOID:0050741
Mondo Disease Ontology
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 21 - 30 of 71 in total
Gene ID Gene Symbol Description Source
1571 CYP2E1 cytochrome P450 family 2 subfamily E member 1
1577 CYP3A5 cytochrome P450 family 3 subfamily A member 5
1588 CYP19A1 cytochrome P450 family 19 subfamily A member 1
1636 ACE angiotensin I converting enzyme
1892 ECHS1 enoyl-CoA hydratase, short chain 1
2348 FOLR1 folate receptor alpha
2571 GAD1 glutamate decarboxylase 1
2572 GAD2 glutamate decarboxylase 2
2597 GAPDH glyceraldehyde-3-phosphate dehydrogenase
2678 GGT1 gamma-glutamyltransferase 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
12846 Comt catechol-O-methyltransferase
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
16846 Lep leptin
Displaying all 3 entries
Gene ID Gene Symbol Description Source
24267 Comt catechol-O-methyltransferase
25608 Lep leptin
29595 Htr2a 5-hydroxytryptamine receptor 2A
The Human Phenotype Ontology
Displaying 1 entry
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
Displaying all 2 entries
Gene ID Gene Symbol Description
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024