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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
alcohol dependence
Summary
- Synonym
-
- alcoholism
- Definition
- A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.
- Super Class
- substance dependence
External Links
- Disease Ontology
- DOID:0050741
- Mondo Disease Ontology
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 6532 | SLC6A4 | solute carrier family 6 member 4 | |
| 7520 | XRCC5 | X-ray repair cross complementing 5 | |
| 8864 | PER2 | period circadian regulator 2 | |
| 9312 | KCNB2 | potassium voltage-gated channel subfamily B member 2 | |
| 9369 | NRXN3 | neurexin 3 | |
| 26523 | AGO1 | argonaute RISC component 1 | |
| 27161 | AGO2 | argonaute RISC catalytic component 2 | |
| 50628 | GEMIN4 | gem nuclear organelle associated protein 4 | |
| 50833 | TAS2R16 | taste 2 receptor member 16 | |
| 91227 | GGTLC2 | gamma-glutamyltransferase light chain 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 13489 | Drd2 | dopamine receptor D2 | |
| 14281 | Fos | FBJ osteosarcoma oncogene | |
| 14395 | Gabra2 | gamma-aminobutyric acid type A receptor subunit alpha 2 | |
| 14402 | Gabrb3 | GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3 | |
| 14406 | Gabrg2 | gamma-aminobutyric acid type A receptor, subunit gamma 2 | |
| 14415 | Gad1 | glutamate decarboxylase 1 | |
| 14573 | Gdnf | glial cell line derived neurotrophic factor | |
| 14598 | Ggt1 | gamma-glutamyltransferase 1 | |
| 14811 | Grin2a | glutamate receptor, ionotropic, NMDA2A (epsilon 1) | |
| 14823 | Grm8 | glutamate receptor, metabotropic 8 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 81646 | Creb1 | cAMP responsive element binding protein 1 | |
| 81657 | Gabbr1 | gamma-aminobutyric acid type B receptor subunit 1 | |
| 83840 | Rps6kb1 | ribosomal protein S6 kinase B1 | |
| 89807 | Angpt1 | angiopoietin 1 | |
| 116508 | Nrxn3 | neurexin 3 | |
| 116568 | Ggt1 | gamma-glutamyltransferase 1 | |
| 171131 | Chrnb3 | cholinergic receptor nicotinic beta 3 subunit | |
| 286963 | Cyp2d5 | cytochrome P450, family 2, subfamily d, polypeptide 5 | |
| 310738 | Ngf | nerve growth factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31251 | per | period | |
| 31309 | dnc | dunce | |
| 31364 | Fas2 | Fasciclin 2 | |
| 32554 | Lcch3 | Ligand-gated chloride channel homolog 3 | |
| 32674 | RSG7 | Regulator of G-protein signaling 7 | |
| 33007 | Dop2R | Dopamine 2-like receptor | |
| 34950 | Ca-alpha1D | Ca[2+]-channel protein alpha[[1]] subunit D | |
| 36411 | sca | scabrous | |
| 36849 | DAT | Dopamine transporter | |
| 37191 | 5-HT1B | 5-hydroxytryptamine (serotonin) receptor 1B |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373802 | pomc.S | proopiomelanocortin S homeolog | Xenopus laevis (African clawed frog) | |
| 378584 | drd2.L | dopamine receptor D2 L homeolog | Xenopus laevis (African clawed frog) | |
| 378605 | htr1a.L | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog | Xenopus laevis (African clawed frog) | |
| 380532 | pomc.L | proopiomelanocortin L homeolog | Xenopus laevis (African clawed frog) | |
| 397761 | ncam1.S | neural cell adhesion molecule 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 397762 | ncam1.L | neural cell adhesion molecule 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) | |
| 100127346 | grin2a.L | glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog | Xenopus laevis (African clawed frog) | |
| 100488055 | cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | Xenopus tropicalis (tropical clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 172105 | unc-38 | Acetylcholine receptor subunit alpha-type unc-38 | |
| 172150 | unc-63 | Acetylcholine receptor subunit alpha-type unc-63 | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 176304 | dat-1 | Sodium-dependent dopamine transporter | |
| 176691 | gab-1 | Gamma-aminobutyric acid receptor subunit beta | |
| 177911 | Y43C5A.2 | Fibrinogen C-terminal domain-containing protein | |
| 177940 | egl-21 | Carboxypeptidase E | |
| 178269 | lev-1 | Acetylcholine receptor subunit beta-type lev-1 | |
| 179347 | dop-2 | Dopamine receptor 2 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
