neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 106 in total
Gene ID Gene Symbol Description Source
50 ACO2 aconitase 2
334 APLP2 amyloid beta precursor like protein 2
387 RHOA ras homolog family member A
388 RHOB ras homolog family member B
389 RHOC ras homolog family member C
847 CAT catalase
1778 DYNC1H1 dynein cytoplasmic 1 heavy chain 1
1855 DVL1 dishevelled segment polarity protein 1
1857 DVL3 dishevelled segment polarity protein 3
2011 MARK2 microtubule affinity regulating kinase 2
Displaying entries 21 - 30 of 73 in total
Gene ID Gene Symbol Description Source
19170 Psmb1 proteasome (prosome, macropain) subunit, beta type 1
19179 Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1
19206 Ptch1 patched 1
19207 Ptch2 patched 2
20276 Scnn1a sodium channel, nonvoltage-gated 1 alpha
20277 Scnn1b sodium channel, nonvoltage-gated 1 beta
20278 Scnn1g sodium channel, nonvoltage-gated 1 gamma
20510 Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
20511 Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
20512 Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
Displaying entries 1 - 10 of 33 in total
Gene ID Gene Symbol Description Source
24335 Epo erythropoietin
24408 Grin1 glutamate ionotropic receptor NMDA type subunit 1
24767 Scnn1b sodium channel epithelial 1 subunit beta
24768 Scnn1g sodium channel epithelial 1 subunit gamma
24849 Tpi1 triosephosphate isomerase 1
25122 Scnn1a sodium channel epithelial 1 subunit alpha
25550 Slc1a1 solute carrier family 1 member 1
25721 Got2 glutamic-oxaloacetic transaminase 2
29482 Slc1a2 solute carrier family 1 member 2
29483 Slc1a3 solute carrier family 1 member 3
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
38742 GluRIA Glutamate receptor IA
38895 Sarm Sterile alpha and Armadillo motif
39836 st scarlet
40665 Nmdar1 NMDA receptor 1
43582 Tpi Triose phosphate isomerase
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
181035 deg-1 Degenerin deg-1
181166 pkc-2 Protein kinase C;Protein kinase C-like 2
181728 mec-4 Degenerin mec-4
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188744 glt-4 Amino acid transporter;Putative sodium-dependent excitatory amino acid transporter glt-4
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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