asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
External Links
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 221 - 222 of 222 in total
Gene ID Gene Symbol Description Source
653509 SFTPA1 surfactant protein A1
729238 SFTPA2 surfactant protein A2
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
12654 Chi3l1 chitinase 3 like 1
12655 Chil3 chitinase-like 3
16182 Il18r1 interleukin 18 receptor 1
16846 Lep leptin
17082 Il1rl1 interleukin 1 receptor-like 1
18654 Pgf placental growth factor
18783 Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent)
21897 Tlr1 toll-like receptor 1
21898 Tlr4 toll-like receptor 4
21899 Tlr6 toll-like receptor 6
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source
24835 Tnf tumor necrosis factor
25556 Il1rl1 interleukin 1 receptor-like 1
25591 Parp1 poly (ADP-ribose) polymerase 1
25608 Lep leptin
29260 Tlr4 toll-like receptor 4
65270 Abo3 histo-blood group ABO system transferase 3
89824 Chi3l1 chitinase 3 like 1
94203 Pgf placental growth factor
113901 Chia chitinase, acidic
296504 Abo2 histo-blood group ABO system transferase 2
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
3355116 Cht10 Chitinase 10
Displaying all 7 entries
Gene ID Gene Symbol Description Source
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
560788 parp1 poly (ADP-ribose) polymerase 1
563897 gbgt1l5 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5
566487 gbgt1l2 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2
100005565 gbgt1l8 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8
100005704 gbgt1l9 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 9
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo.1 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100497509 abo.4 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 Xenopus tropicalis (tropical clawed frog)
108698211 abo.2.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog Xenopus laevis (African clawed frog)
108698863 abo.4.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog Xenopus laevis (African clawed frog)
Displaying all 3 entries
Gene ID Gene Symbol Description Source
180628 cht-1 putative endochitinase
183000 gsto-1 Glutathione transferase omega-1
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
850666 GTT2 glutathione transferase GTT2
851977 CTS2 putative chitinase
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
HP:0000006 Autosomal dominant inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024