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asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5729 | PTGDR | prostaglandin D2 receptor | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | |
| 6347 | CCL2 | C-C motif chemokine ligand 2 | |
| 6352 | CCL5 | C-C motif chemokine ligand 5 | |
| 6356 | CCL11 | C-C motif chemokine ligand 11 | |
| 6369 | CCL24 | C-C motif chemokine ligand 24 | |
| 6440 | SFTPC | surfactant protein C | |
| 6441 | SFTPD | surfactant protein D | |
| 6532 | SLC6A4 | solute carrier family 6 member 4 | |
| 6648 | SOD2 | superoxide dismutase 2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| A8K7I4 | Calcium-activated chloride channel regulator 1 | |
| O00175 | C-C motif chemokine 24 | |
| O00206 | Toll-like receptor 4 | |
| O15455 | Toll-like receptor 3 | |
| O15553 | Pyrin | |
| O60603 | Toll-like receptor 2 | |
| O95163 | Elongator complex protein 1 | |
| P01024 | Complement C3 | |
| P01031 | Complement C5 | |
| P01137 | Transforming growth factor beta-1 proprotein |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P16382 | Interleukin-4 receptor subunit alpha | |
| Q9D2L4 | Integrin beta |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P42203 | Interleukin-13 | |
| P97545 | Eotaxin | |
| Q05028 | Platelet-derived growth factor subunit B (Fragment) | |
| Q08125 | Interleukin-5 | |
| Q63495 | Advanced glycosylation end product-specific receptor | |
| Q6RI86 | Transient receptor potential cation channel subfamily A member 1 | |
| Q8K3U6 | Coagulation factor VII |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9VP04 | ORM1-like protein |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
