pulmonary fibrosis

Summary
Synonym
  • Fibrosis of lung
Definition
An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
Super Class
interstitial lung disease
Disease Ontology
DOID:3770
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
182 JAG1 jagged canonical Notch ligand 1
183 AGT angiotensinogen
240 ALOX5 arachidonate 5-lipoxygenase
301 ANXA1 annexin A1
572 BAD BCL2 associated agonist of cell death
623 BDKRB1 bradykinin receptor B1
627 BDNF brain derived neurotrophic factor
847 CAT catalase
948 CD36 CD36 molecule (CD36 blood group)
Displaying entries 11 - 20 of 56 in total
Gene ID Gene Symbol Description Source
12773 Ccr4 C-C motif chemokine receptor 4
12774 Ccr5 C-C motif chemokine receptor 5
12776 Ccr8 C-C motif chemokine receptor 8
12842 Col1a1 collagen, type I, alpha 1
12843 Col1a2 collagen, type I, alpha 2
12981 Csf2 colony stimulating factor 2 (granulocyte-macrophage)
13649 Egfr epidermal growth factor receptor
13653 Egr1 early growth response 1
15234 Hgf hepatocyte growth factor
15510 Hspd1 heat shock protein 1 (chaperonin)
Displaying entries 1 - 10 of 42 in total
Gene ID Gene Symbol Description Source
24179 Agt angiotensinogen
24225 Bdnf brain-derived neurotrophic factor
24260 Chrm3 cholinergic receptor, muscarinic 3
24310 Ace angiotensin I converting enzyme
24446 Hgf hepatocyte growth factor
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
24617 Serpine1 serpin family E member 1
24770 Ccl2 C-C motif chemokine ligand 2
24773 Sftpa1 surfactant protein A1
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
31293 N Notch
31926 Idgf4 Imaginal disc growth factor 4
34189 Acer Angiotensin-converting enzyme-related
34282 GlcAT-S Glucuronyltransferase S
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30718 notch1a notch receptor 1a
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
140421 jag1a jagged canonical Notch ligand 1a
386856 pdgfra platelet-derived growth factor receptor, alpha polypeptide
548607 b3gat1a beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100332644 b3gat1b beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
100037907 b3gat1 beta-1,3-glucuronyltransferase 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174517 sqv-8 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175781 daf-4 Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase
176286 glp-1 glp-1/Notch intracellular domain
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178672 srp-3 Serpin domain-containing protein
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179962 gar-3 Muscarinic acetylcholine receptor gar-3
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851977 CTS2 putative chitinase
853177 APL6 Apl6p

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