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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
macular degeneration
Summary
- Synonym
-
- Macular degeneration of retina
- Definition
- A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.
- Super Class
- retinal degeneration
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24 | ABCA4 | ATP binding cassette subfamily A member 4 | |
| 348 | APOE | apolipoprotein E | |
| 355 | FAS | Fas cell surface death receptor | |
| 572 | BAD | BCL2 associated agonist of cell death | |
| 581 | BAX | BCL2 associated X, apoptosis regulator | |
| 629 | CFB | complement factor B | |
| 652 | BMP4 | bone morphogenetic protein 4 | |
| 710 | SERPING1 | serpin family G member 1 | |
| 717 | C2 | complement C2 | |
| 718 | C3 | complement C3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 18024 | Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | |
| 18979 | Pon1 | paraoxonase 1 | |
| 19017 | Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | |
| 19133 | Prph2 | peripherin 2 | |
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20317 | Serpinf1 | serine (or cysteine) peptidase inhibitor, clade F, member 1 | |
| 20655 | Sod1 | superoxide dismutase 1, soluble | |
| 21898 | Tlr4 | toll-like receptor 4 | |
| 54376 | Cacng3 | calcium channel, voltage-dependent, gamma subunit 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24232 | C3 | complement C3 | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24890 | Esr1 | estrogen receptor 1 | |
| 25419 | Crp | C-reactive protein | |
| 25420 | Cryab | crystallin, alpha B | |
| 25534 | Prph2 | peripherin 2 | |
| 25589 | Kdr | kinase insert domain receptor | |
| 26201 | ND4 | NADH dehydrogenase subunit 4 | |
| 29260 | Tlr4 | toll-like receptor 4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 33432 | dpp | decapentaplegic | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 36232 | Sod3 | Superoxide dismutase 3 | |
| 38868 | Snmp2 | Sensory neuron membrane protein 2 | |
| 41840 | Hsc70-4 | Heat shock protein 70 cognate 4 | |
| 42514 | Snmp1 | Sensory neuron membrane protein 1 | |
| 43222 | Tl | Toll |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 398002 | prph2.S | peripherin 2 (retinal degeneration, slow) S homeolog | Xenopus laevis (African clawed frog) | |
| 399322 | bmp4.S | bone morphogenetic protein 4 S homeolog | Xenopus laevis (African clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171782 | abt-2 | ABC transporter domain-containing protein | |
| 171999 | poml-2 | Arylesterase | |
| 175182 | ver-1 | Protein ver-1 | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179068 | dbl-1 | Protein dbl-1 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180812 | scav-1 | SCAVenger receptor (CD36 family) related | |
| 186632 | ver-4 | Tyrosine-protein kinase receptor ver-4 |
