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Standards Ontologies Notations
diabetes mellitus

Summary
Synonym
  • diabetes
Definition
A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
Super Class
glucose metabolism disease
Disease Ontology
DOID:9351
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 84 in total
Gene ID Gene Symbol Description Source
654 BMP6 bone morphogenetic protein 6
655 BMP7 bone morphogenetic protein 7
656 BMP8B bone morphogenetic protein 8b
959 CD40LG CD40 ligand
999 CDH1 cadherin 1
1080 CFTR CF transmembrane conductance regulator
1361 CPB2 carboxypeptidase B2
1436 CSF1R colony stimulating factor 1 receptor
1508 CTSB cathepsin B
1543 CYP1A1 cytochrome P450 family 1 subfamily A member 1
Displaying entries 11 - 20 of 72 in total
Gene ID Gene Symbol Description Source
12550 Cdh1 cadherin 1
12638 Cftr cystic fibrosis transmembrane conductance regulator
12753 Clock clock circadian regulator
12978 Csf1r colony stimulating factor 1 receptor
13030 Ctsb cathepsin B
13076 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
13095 Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29
13649 Egfr epidermal growth factor receptor
14066 F3 coagulation factor III
14068 F7 coagulation factor VII
Displaying entries 1 - 10 of 46 in total
Gene ID Gene Symbol Description Source
24255 Cftr CF transmembrane conductance regulator
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24385 Gck glucokinase
24446 Hgf hepatocyte growth factor
24464 Hp haptoglobin
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24617 Serpine1 serpin family E member 1
Displaying entry 21 - 21 of 21 in total
Gene ID Gene Symbol Description Source
3772574 Fuca alpha-L-fucosidase
Displaying all 6 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
64274 csf1ra colony stimulating factor 1 receptor, a
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
322857 prom1a prominin 1a
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
559080 cftr CF transmembrane conductance regulator
Displaying all 8 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178748 zmp-3 Matrix metalloproteinase-C
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
179197 cri-2 Putative metalloproteinase inhibitor tag-225
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850462 GIT1 Git1p
850614 HXK1 hexokinase 1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852128 EMI2 putative glucokinase
852543 VVS1 Vvs1p
852639 HXK2 hexokinase 2
853978 NFT1 putative multidrug transporter NFT1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024