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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
External Links
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 441 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
31 ACACA acetyl-CoA carboxylase alpha
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
43 ACHE acetylcholinesterase (Yt blood group)
47 ACLY ATP citrate lyase
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
155 ADRB3 adrenoceptor beta 3
Displaying entries 21 - 30 of 54 in total
Gene ID Gene Symbol Description Source
16591 Kl klotho
16846 Lep leptin
16847 Lepr leptin receptor
18294 Ogg1 8-oxoguanine DNA-glycosylase 1
18534 Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
18609 Pdx1 pancreatic and duodenal homeobox 1
18708 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
19045 Ppp1ca protein phosphatase 1 catalytic subunit alpha
Displaying entries 1 - 10 of 50 in total
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24385 Gck glucokinase
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24536 Lepr leptin receptor
Displaying entries 21 - 30 of 46 in total
Gene ID Gene Symbol Description Source
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
42518 Oga O-GlcNAcase
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
42620 PyK Pyruvate kinase
43183 Ald1 Aldolase 1
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
43223 Lerp lysosomal enzyme receptor protein
43708 Ugt35D1 UDP-glycosyltransferase family 35 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
560788 parp1 poly (ADP-ribose) polymerase 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
407879 ppp1cc protein phosphatase 1, catalytic subunit, gamma isozyme Xenopus tropicalis (tropical clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
Displaying all 8 entries
Gene ID Gene Symbol Description Source
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
175591 ugt-62 UDP-glucuronosyltransferase
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
176788 aldo-1 Fructose-bisphosphate aldolase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180628 cht-1 putative endochitinase
189173 W03G11.3 Putative alpha-L-fucosidase
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
851977 CTS2 putative chitinase
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
854350 GAC1 protein phosphatase regulator GAC1
Related Glycoprotein
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
6514 SLC2A2 solute carrier family 2 member 2
2645 GCK glucokinase
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
3990 LIPC lipase C, hepatic type
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024