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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 41 - 50 of 133 in total
Gene ID Gene Symbol Description Source
2638 GC GC vitamin D binding protein
2689 GH2 growth hormone 2
2690 GHR growth hormone receptor
2878 GPX3 glutathione peroxidase 3
3065 HDAC1 histone deacetylase 1
3066 HDAC2 histone deacetylase 2
3113 HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
3115 HLA-DPB1 major histocompatibility complex, class II, DP beta 1
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
Displaying entries 81 - 90 of 102 in total
Gene ID Gene Symbol Description Source
21857 Timp1 tissue inhibitor of metalloproteinase 1
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
21939 Cd40 CD40 antigen
21947 Cd40lg CD40 ligand
22035 Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10
22041 Trf transferrin
22164 Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4
22329 Vcam1 vascular cell adhesion molecule 1
22371 Vwf Von Willebrand factor
Displaying entries 1 - 10 of 61 in total
Gene ID Gene Symbol Description Source
24221 Avp arginine vasopressin
24232 C3 complement C3
24310 Ace angiotensin I converting enzyme
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24464 Hp haptoglobin
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
Displaying entries 21 - 30 of 43 in total
Gene ID Gene Symbol Description Source
40079 Ugt316A1 UDP-glycosyltransferase family 316 member A1
40653 PEK pancreatic eIF-2alpha kinase
41334 Ugt35A1 UDP-glycosyltransferase family 35 member A1
41549 Octbeta2R Octopamine beta2 receptor
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
41625 Ace Acetylcholine esterase
42490 Mvl Malvolio
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
42679 wfs1 wolfram syndrome 1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024