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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 133 in total
Gene ID Gene Symbol Description Source
43 ACHE acetylcholinesterase (Yt blood group)
153 ADRB1 adrenoceptor beta 1
177 AGER advanced glycosylation end-product specific receptor
217 ALDH2 aldehyde dehydrogenase 2 family member
335 APOA1 apolipoprotein A1
336 APOA2 apolipoprotein A2
338 APOB apolipoprotein B
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
355 FAS Fas cell surface death receptor
Displaying entries 61 - 70 of 102 in total
Gene ID Gene Symbol Description Source
17967 Ncam1 neural cell adhesion molecule 1
18132 Notch4 notch 4
18173 Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
18609 Pdx1 pancreatic and duodenal homeobox 1
18646 Prf1 perforin 1 (pore forming protein)
18791 Plat plasminogen activator, tissue
18979 Pon1 paraoxonase 1
19276 Ptprn2 protein tyrosine phosphatase receptor type N polypeptide 2
19692 Reg1 regenerating islet-derived 1
20292 Ccl11 C-C motif chemokine ligand 11
Displaying entries 11 - 20 of 61 in total
Gene ID Gene Symbol Description Source
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24586 Ncam1 neural cell adhesion molecule 1
24714 Reg1a regenerating family member 1 alpha
24770 Ccl2 C-C motif chemokine ligand 2
24787 Sod2 superoxide dismutase 2
24825 Tf transferrin
24835 Tnf tumor necrosis factor
24861 Ugt1a1 UDP glucuronosyltransferase family 1 member A1
24925 Adrb1 adrenoceptor beta 1
Displaying entries 21 - 30 of 43 in total
Gene ID Gene Symbol Description Source
40079 Ugt316A1 UDP-glycosyltransferase family 316 member A1
40653 PEK pancreatic eIF-2alpha kinase
41334 Ugt35A1 UDP-glycosyltransferase family 35 member A1
41549 Octbeta2R Octopamine beta2 receptor
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
41625 Ace Acetylcholine esterase
42490 Mvl Malvolio
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
42679 wfs1 wolfram syndrome 1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024